flict- fligo to strike down

afflicted children typically present with failure to thrive and visual problems due to lens displacement.

the autosomal recessive form is much more severe, with only a few afflicted children surviving in to infancy. (osteopetrosis)

severely afflicted patients are unable to leave the supine position without experiencing presyncope or syncope.(uptodate)

WordNet

cause physical pain or suffering in; "afflict with the plague" (同)smite
cause great unhappiness for; distress; "she was afflicted by the death of her parents"
weight down with a load (同)burthen, weight, weight down
an onerous or difficult concern; "the burden of responsibility"; "thats a load off my mind" (同)load, encumbrance, incumbrance, onus
the central idea that is expanded in a document or discourse
a condition of suffering or distress due to ill health
a state of great suffering and distress due to adversity
a cause of great suffering and distress
causing misery or pain or distress; "it was a sore trial to him"; "the painful process of growing up" (同)painful, sore
grievously affected especially by disease (同)stricken
mentally or physically unfit (同)impaired

PrepTutorEJDIC

(肉体的に,精神的に)(…で)…'を'『苦しめる』,悩ます(distress)《+『名』+『with』+『名』 (a person's do『ing』)》
〈C〉『荷物』,『積荷』 / 〈U〉荷物の運搬 / 〈C〉(…にとっての)(心を)『重荷』,苦しみ,悩み《+『to』(『on』)+『名』》 / (荷を)…‘に'『負わせる』,積む《+『名』~『with』+『名』〈荷〉》
〈C〉(歌の)折り返し / 《the ~》くり返し説かれる要旨(主旨)
(心身の)苦悩,難儀 / 苦悩(悩み)を引き起こすもの

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