活性化転写因子

関: ATF

WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
(genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
a sound or television recording (e.g., from a broadcast to a tape recording)
something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
causing motion or action or change (同)actuating

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/11/19 01:06:34」(JST)

wiki en

[Wiki en表示]

In molecular biology, activating transcription factor, ATF, is a class of AP-1 transcription factor dimers.^[1]

Genes include ATF1, ATF2, ATF3, ATF4, ATF5, ATF6, and ATF7.

References

^ van Dam H, Castellazzi M (2001). "Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis". Oncogene 20 (19): 2453–64. doi:10.1038/sj.onc.1204239. PMID 11402340.

External links

Activating+Transcription+Factors at the US National Library of Medicine Medical Subject Headings (MeSH)

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UpToDate Contents

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English Journal

Caveolin-1 is a novel regulator of K-RAS-dependent migration in colon carcinogenesis.

Basu Roy UK, Henkhaus RS, Loupakis F, Cremolini C, Gerner EW, Ignatenko NA.SourceDepartment of Biochemistry and Molecular Biophysics, Biochemistry and Molecular and Cellular Biology Graduate Program, University of Arizona, Tucson, AZ, USA.
International journal of cancer. Journal international du cancer.Int J Cancer.2013 Jul;133(1):43-57. doi: 10.1002/ijc.28001. Epub 2013 Feb 12.
Caveolin-1 is an essential component of membrane caveolae. It is an important regulator of cellular processes such as signal transduction and endocytosis. We report here, for the first time, that caveolin-1 is a target of the K-RAS oncogene in colon carcinogenesis. Caveolin-1 is induced in colon can
PMID 23280667

MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization.

Lyberopoulou A, Mylonis I, Papachristos G, Sagris D, Kalousi A, Befani C, Liakos P, Simos G, Georgatsou E.SourceLaboratory of Biochemistry, School of Medicine, University of Thessaly, Biopolis 41110, Larissa, Greece.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Jun;1833(6):1378-87. doi: 10.1016/j.bbamcr.2013.02.025. Epub 2013 Feb 28.
Hypoxia inducible factor-1 (HIF-1), a dimeric transcription factor of the bHLH-PAS family, is comprised of HIF-1α, which is inducible by hypoxia and ARNT or HIF-1β, which is constitutively expressed. HIF-1 is involved in cellular homeostasis under hypoxia, in development and in several diseases af
PMID 23458834

The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells.

Xu F, You X, Liu F, Shen X, Yao Y, Ye L, Zhang X.SourceDepartment of Cancer Research, Key Laboratory of Molecular Microbiology and Technology of Ministry of Education, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071, PR China; School of Medicine, Nankai University, Tianjin 300071, PR China; Department of Gynecology and Obstetrics, PLA General Hospital, Beijing 100853, PR China.
Cancer letters.Cancer Lett.2013 Jun 1;333(1):124-32. doi: 10.1016/j.canlet.2013.01.029. Epub 2013 Jan 22.
Hepatitis B X-interacting protein (HBXIP) is a novel oncoprotein. In this study, we found that the expression levels of HBXIP were positively associated with those of S-phase kinase-associated protein 2 (Skp2) in clinical breast cancer tissues and cell lines. Moreover, we found that HBXIP was able t
PMID 23352642

Japanese Journal

LIM-homeodomain transcription factor Awh is a key component activating all three fibroin genes, fibH, fibL and fhx, in the silk gland of the silkworm, Bombyx mori

Kimoto Mai,Tsubota Takuya,Uchino Keiro,Sezutsu Hideki,Takiya Shigeharu
Insect biochemistry and molecular biology 56, 29-35, 2015-01
… Silk gland factor-2 (SGF-2) is a PSG-specific activator complex of fibH, composed of a LIM-homeodomain protein, Awh, and its cofactors, Ldb and Lcaf. …
NAID 120005567736

Renal Nerve-Mediated Erythropoietin Release Confers Cardioprotection During Remote Ischemic Preconditioning

, , , , , , , , , , , , , , , , , ,
Circulation Journal advpub(0), 2015
… This study aimed to investigate the mechanisms underlying the RIPC-induced production of Janus kinase (JAK)-signal transducer and activator of the transcription (STAT)-activating cytokines and cardioprotection by using mouse and human models of RIPC.Methods and Results:Screened circulating cardioprotective JAK-STAT-activating cytokines in mice unexpectedly revealed increased serum erythropoietin (EPO) levels after RIP induced by transient ischemia. …
NAID 130005063501

Silencing of IFN-stimulated gene transcription is regulated by histone H1 and its chaperone TAF-I

Kadota Shinichi,Nagata Kyosuke
Nucleic acids research 42(12), 7642-7653, 2014-08
… Chromatin structure and its alteration play critical roles in the regulation of transcription. … Here we investigated the role of template activating factor-I (TAF-I, also known as SET) in ISG transcription. … Knockdown (KD) of TAF-I increased ISG transcript and simultaneously reduced the histone H1 level on the ISG promoters during the early stages of transcription after IFN stimulation from the unstimulated state. …
NAID 120005477889

「ATF」

　　[★]

活性化転写因子

関: activating transcription factor

「活性化転写因子」

　　[★]

英: activating transcription factor、ATF

「activating transcription factor 1」

　　[★]

活性化転写因子1、転写因子ATF1

関: ATF1

「activating transcription factor 2」

　　[★]

活性化転写因子2、転写因子ATF2

関: ATF2

「activating transcription factor 4」

　　[★]

活性化転写因子4、転写因子ATF4

関: ATF4

「activating transcription factor 6」

　　[★]

活性化転写因子6

関: ATF6

「fact」

　　[★]

n.

事実、現状、実際、実態

関: actual、actually、in fact、in practice、indeed、practically

「factor」

　　[★]

n.

因子、要因、要素、ファクター

関: element、elementary、factorial、parameter

「transcription factor」

　　[★]

転写制御因子、転写因子

関: TF、transcriptional regulator、transcriptional regulatory element

[van_Dam-1] van Dam H, Castellazzi M (2001). "Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis". Oncogene 20 (19): 2453–64. doi:10.1038/sj.onc.1204239. PMID 11402340.

リンク元	「ATF」「活性化転写因子」
拡張検索	「activating transcription factor 1」「activating transcription factor 2」「activating transcription factor 4」「activating transcription factor 6」
関連記事	「fact」「factor」「transcription factor」

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案内

案内

activating transcription factor