RNA-dependent protein kinase

• RNA依存性プロテインキナーゼ

関

eIF-2 kinase、eIF-2alpha kinase、PKR、RNA-activated protein kinase

WordNet

1. relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
2. addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
3. contingent on something else (同)dependant, qualified
4. (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
5. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
6. the 18th letter of the Roman alphabet (同)r
7. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

PrepTutorEJDIC

1. 『頼っている』,依存している,従属している / 扶養される人(家族)
2. 蛋白(たんばく)質
3. resistance / 17歳以下父兄同伴映画の表示 / rook
4. ribonucleic acid・リボ核酸

UpToDate Contents

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• 1. 未分化リンパ腫キナーゼ（ALK）融合癌遺伝子陽性非小細胞肺癌 anaplastic lymphoma kinase alk fusion oncogene positive non small cell lung cancer
• 2. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
• 3. 複合免疫不全 combined immunodeficiencies
• 4. 黒色腫（メラノーマ）の分子生物学 the molecular biology of melanoma
• 5. 脊髄小脳変性症 the spinocerebellar ataxias

English Journal

• Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes.

• Sciarretta S1, Yee D1, Ammann P1, Nagarajan N1, Volpe M2, Frati G2, Sadoshima J1.
• Clinical science (London, England : 1979).Clin Sci (Lond).2015 Apr;128(7):387-403. doi: 10.1042/CS20140336.
• In the past several years, it has been demonstrated that the reactive oxygen species (ROS) may act as intracellular signalling molecules to activate or inhibit specific signalling pathways and regulate physiological cellular functions. It is now well-established that ROS regulate autophagy, an intra
• PMID 25515000

• Crucial roles of canonical Runx2-dependent pathway on Wnt1-induced osteoblastic differentiation of human periodontal ligament fibroblasts.

• Kook SH1, Heo JS, Lee JC.
• Molecular and cellular biochemistry.Mol Cell Biochem.2015 Apr;402(1-2):213-23. doi: 10.1007/s11010-015-2329-y. Epub 2015 Jan 25.
• Canonical Wnt signaling is thought to enhance osteogenic differentiation of human periodontal ligament fibroblasts (hPLFs). However, the mechanism of this enhancement has not yet been defined. We investigated the effects of Wnt1 on osteoblast differentiation of hPLFs and explored the mechanisms of t
• PMID 25618247

• SAMHD1 prevents autoimmunity by maintaining genome stability.

• Kretschmer S1, Wolf C1, König N1, Staroske W2, Guck J3, Häusler M4, Luksch H1, Nguyen LA5, Kim B6, Alexopoulou D7, Dahl A7, Rapp A8, Cardoso MC8, Shevchenko A9, Lee-Kirsch MA1.
• Annals of the rheumatic diseases.Ann Rheum Dis.2015 Mar;74(3):e17. doi: 10.1136/annrheumdis-2013-204845. Epub 2014 Jan 20.
• OBJECTIVES: The HIV restriction factor, SAMHD1 (SAM domain and HD domain-containing protein 1), is a triphosphohydrolase that degrades deoxyribonucleoside triphosphates (dNTPs). Mutations in SAMHD1 cause Aicardi-Goutières syndrome (AGS), an inflammatory disorder that shares phenotypic similarity wi
• PMID 24445253

Japanese Journal

• The Role of Double-stranded RNA-dependent Protein Kinase in Osteoblasts

• YOSHIDA Kaya
• Journal of oral biosciences 49(3), 155-162, 2007-08-20
• NAID 10027102656

• Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro

• Yoshida K,Okamura H,Amorim BR,Ozaki A,Tanaka H,Morimoto H,Haneji T
• EXPERIMENTAL CELL RESEARCH 311(1), 117-125, 2005
• NAID 80017741807

Related Links

• Deficient signaling in mice devoid of double-stranded RNA ...

Abstract Double-stranded RNA-dependent protein kinase (PKR) has been implicated in interferon (IFN) induction, antiviral response and tumor suppression. We have generated mice devoid of functional PKR (Pkr%). Although the mice ...

• Essential Role for the dsRNA-Dependent Protein Kinase PKR ...

The double-stranded (ds) RNA-dependent protein kinase PKR is considered to play an important role in interferon's (IFN's) response to viral infection. Here, we ... Figure 1. Ablation of PKR in EFs from Mice with a Targeted Disruption ...

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★リンクテーブル★

リンク元	「RNA依存性プロテインキナーゼ」「RNA-activated protein kinase」
拡張検索	「double-stranded RNA-dependent protein kinase」
関連記事	「R」「dependent」「RNA」「kinase」「protein kinase」

「RNA依存性プロテインキナーゼ」

　　[★]

英

RNA-dependent protein kinase、PKR

関

真核生物翻訳開始因子2キナーゼ、真核生物翻訳開始因子2αキナーゼ、RNA活性化プロテインキナーゼ

「RNA-activated protein kinase」

　　[★]

• RNA活性化プロテインキナーゼ

関

eIF-2 kinase、eIF-2alpha kinase、PKR、RNA-dependent protein kinase

「double-stranded RNA-dependent protein kinase」

　　[★]

• 二本鎖RNA依存性プロテインキナーゼ

「R」

　　[★]

• レントゲン roentgen
• アルギニン
• respiratory rate
• respiratory quotient
• プリン
• アルキル基 alkyl group
• 化合物の側鎖

　 　

「dependent」

　　[★]

• adj.

• 依存性の、依存的な、依存型の、依存の

関

depend、dependence、dependency、dependently

　 　 　 　 　

「RNA」

　　[★]

同

リボ核酸 ribonucleic acid RNA

関

DNA

• D-リボースを糖成分とする核酸

　

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「protein kinase」

　　[★] プロテインキナーゼ

同

protein kinases