RNA-activated protein kinase

• RNA活性化プロテインキナーゼ

関

eIF-2 kinase、eIF-2alpha kinase、PKR、RNA-dependent protein kinase

WordNet

1. aerate (sewage) so as to favor the growth of organisms that decompose organic matter (同)aerate
2. make (substances) radioactive
3. make active or more active; "activate an old file"
4. make more adsorptive; "activate a metal"
5. rendered active; e.g. rendered radioactive or luminescent or photosensitive or conductive
6. (of e.g. a molecule) made reactive or more reactive (同)excited
7. (military) set up and placed on active assignment; "a newly activated unit"
8. (of sewage) treated with aeration and bacteria to aid decomposition
9. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
10. the 18th letter of the Roman alphabet (同)r
11. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme

PrepTutorEJDIC

1. …'を'活動的にする / …‘に'放射能を与える / 〈物質〉'を'活性化する
2. 蛋白(たんばく)質
3. resistance / 17歳以下父兄同伴映画の表示 / rook

UpToDate Contents

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• 1. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
• 2. 未分化リンパ腫キナーゼ（ALK）融合癌遺伝子陽性非小細胞肺癌 anaplastic lymphoma kinase alk fusion oncogene positive non small cell lung cancer
• 3. 黒色腫（メラノーマ）の分子生物学 the molecular biology of melanoma
• 4. 喘息における吸入ステロイドの分子学的影響 molecular effects of inhaled glucocorticoid therapy in asthma
• 5. 甲状腺結節および非髄様甲状腺癌におけるオンコジーンおよび腫瘍抑制遺伝子 oncogenes and tumor suppressor genes in thyroid nodules and nonmedullary thyroid cancer

English Journal

• Adenovirus VA RNA: An essential pro-viral non-coding RNA.

• Vachon VK1, Conn GL2.
• Virus research.Virus Res.2015 Jun 25. pii: S0168-1702(15)00283-X. doi: 10.1016/j.virusres.2015.06.018. [Epub ahead of print]
• Adenovirus (AdV) 'virus-associated' RNAs (VA RNAs) are exceptionally abundant (up to 108copies/cell), heterogeneous, non-coding RNA transcripts (∼150-200 nucleotides). The predominant species, VA RNAI, is best recognized for its essential function in relieving the cellular anti-viral blockade of p
• PMID 26116898

• Adenovirus VA RNA: An essential pro-viral non-coding RNA.

• Vachon VK1, Conn GL2.
• Virus research.Virus Res.2015 Jun 23. pii: S0168-1702(15)30001-0. doi: 10.1016/j.virusres.2015.06.020. [Epub ahead of print]
• Adenovirus (AdV) 'virus-associated' RNAs (VA RNAs) are exceptionally abundant (up to 108 copies per cell), heterogeneous, non-coding RNA transcripts (∼150-200 nucleotides). The predominant species, VA RNAI, is best recognized for its essential function in relieving the cellular anti-viral blockade
• PMID 26116275

• A kinome-wide siRNA screen identifies proviral and antiviral host factors in SARS-coronavirus replication, including PKR and early secretory pathway proteins.

• de Wilde AH1, Wannee KF1, Scholte FE1, Goeman JJ2, Ten Dijke P3, Snijder EJ1, Kikkert M4, van Hemert MJ4.
• Journal of virology.J Virol.2015 Jun 3. pii: JVI.01029-15. [Epub ahead of print]
• To identify host factors relevant for SARS-coronavirus (SARS-CoV) replication, we performed an siRNA library screen targeting the human kinome. Protein kinases are key regulators of many cellular functions and the systematic knockdown of their expression should provide a broad perspective on factors
• PMID 26041291

Japanese Journal

• Activating Transcription Factor 6 Mediates Oxidized LDL-Induced Cholesterol Accumulation and Apoptosis in Macrophages by Up-Regulating CHOP Expression

• Journal of Atherosclerosis and Thrombosis 20(1), 94-107, 2013
• NAID 130004444637

• Hydroxynaphthoic Acids Identified in a High Throughput Screening Potently Ameliorate Endoplasmic Reticulum Stress as Novel Chemical Chaperones

• Chemical and Pharmaceutical Bulletin 61(7), 740-746, 2013
• NAID 130003360802

• Cadmium induces ER stress and apoptosis in renal proximal tubular cells: protection by salubrinal

• 日本毒性学会学術年会 39.2(0), AP-32, 2012
• NAID 130005009191

Related Links

• Double-stranded RNA-activated protein kinase (PKR) is ...

1. Mol Cell Biol. 1999 Feb;19(2):1116-25. Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18. Kumar KU(1), Srivastava SP, Kaufman RJ. Author information: (1 ...

• Double-stranded RNA-activated protein kinase PKR of fishes ...

1. BMC Biol. 2008 Mar 3;6:12. doi: 10.1186/1741-7007-6-12. Double-stranded RNA-activated protein kinase PKR of fishes and amphibians: varying the number of double-stranded RNA binding domains and lineage-specific duplications.

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★リンクテーブル★

リンク元	「RNA-dependent protein kinase」「RNA活性化プロテインキナーゼ」
拡張検索	「double-stranded RNA-activated protein kinase」
関連記事	「R」「activated」「activate」「RNA」「kinase」

「RNA-dependent protein kinase」

　　[★]

• RNA依存性プロテインキナーゼ

関

eIF-2 kinase、eIF-2alpha kinase、PKR、RNA-activated protein kinase

「RNA活性化プロテインキナーゼ」

　　[★]

英

RNA-activated protein kinase、PKR

関

RNA依存性プロテインキナーゼ

「double-stranded RNA-activated protein kinase」

　　[★]

• 二本鎖RNA活性化プロテインキナーゼ

「R」

　　[★]

• レントゲン roentgen
• アルギニン
• respiratory rate
• respiratory quotient
• プリン
• アルキル基 alkyl group
• 化合物の側鎖

　 　

「activated」

　　[★]

• adj.

• 活性化の、活性化型の、賦活化の

関

activate、activated form、activation、turn on

　 　 　 　

「activate」

　　[★]

• v.

• 活性化する、賦活化する、賦活する

関

activated、activation、turn on

　 　 　 　 　

「RNA」

　　[★]

同

リボ核酸 ribonucleic acid RNA

関

DNA

• D-リボースを糖成分とする核酸

　

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase