WordNet

executed with proper legal authority; "a binding contract"
the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
strip sewn over or along an edge for reinforcement or decoration
the capacity to attract and hold something
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
the 18th letter of the Roman alphabet (同)r

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1. 遺伝性疾患の基本原則 basic principles of genetic disease
2. 鉄のバランス調節 regulation of iron balance
3. ペリツェウス・メルツバッハー病 pelizaeus merzbacher disease
4. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
5. 筋萎縮性側索硬化症の疫学および病因 epidemiology and pathogenesis of amyotrophic lateral sclerosis

EWS represses cofilin 1 expression by inducing nuclear retention of cofilin 1 mRNA.

Huang L, Kuwahara I, Matsumoto K.Source1] Molecular Entomology Laboratory, RIKEN, Wako, Japan [2] Department of Pathophysiology, Dalian Medical University, Dalian, China.
Oncogene.Oncogene.2013 Jul 8. doi: 10.1038/onc.2013.255. [Epub ahead of print]
In Ewing's sarcoma family tumors (ESFTs), the proto-oncogene EWS that encodes an RNA-binding protein is fused by chromosomal translocation to the gene encoding one of the E-twenty six (ETS) family of transcription factors, most commonly friend leukemia virus integration 1 (FLI-1). Although EWS/FLI-1
PMID 23831569

Ovarian tissue cryopreserved for fertility preservation from patients with Ewing or other sarcomas appear to have no tumour cell contamination.

Greve T, Wielenga VT, Grauslund M, Sørensen N, Christiansen DB, Rosendahl M, Yding Andersen C.SourceLaboratory of Reproductive Biology, Rigshospitalet - Copenhagen University Hospital, Denmark. tinegreve@gmail.com
European journal of cancer (Oxford, England : 1990).Eur J Cancer.2013 May;49(8):1932-8. doi: 10.1016/j.ejca.2013.01.032. Epub 2013 Feb 26.
AIM: The chemotherapy required to treat patients with sarcoma may as a side-effect induce infertility in girls and young women. If these patients have ovarian cortical tissue cryopreserved prior to chemotherapy, they may, if necessary, have the tissue transplanted and restore their fertility. The ai
PMID 23452988

Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.

Talbot J, Brion R, Picarda G, Amiaud J, Chesneau J, Bougras G, Stresing V, Tirode F, Heymann D, Redini F, Verrecchia F.SourceLUNAM Université, France.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Apr;1832(4):553-64. doi: 10.1016/j.bbadis.2013.01.001. Epub 2013 Jan 9.
Ewing's sarcoma (ES) is a primary bone tumor characterized by a chromosomic translocation between the EWS gene and a member of the ETS gene family, mainly FLI1, which leads to an aberrant transcription factor EWS-FLI1 that promotes tumorigenicity. Gap junctions are intercellular channels composed of
PMID 23313578

Aberrant Control of Transcription and Transportation of Oncogenic mRNA in Carcinogenesis

Higashino Fumihiro,Hida Kyoko,Kitamura Tetsuya,Ohga Noritaka,Shindoh Masanobu
Oral Science International 7(1), 11-18, 2009
… EWS/ETS fusions are frequently observed in Ewing's sarcoma, and we have revealed that EWS/ETS chimeric protein activates telomerase activity by upregulating human telomerase reverse transcriptase (hTERT), but the transcriptional activation of hTERT by EWS/ETS was indirect, and EWS/ETS was seen to function as a co-activator for TERT transcription. …
NAID 130004503865

Molecular Analysis of Ewing's Sarcoma: Another Fusion Gene, EWS-E1AF, Available for Diagnosis

URANO Fumihiko,UMEZAWA Akihiro,YABE Hiroki,HONG Wei,YOSHIDA Koichi,FUJINAGA Kei,HATA Jun-ichi
Japanese journal of cancer research : gann 89(7), 703-711, 1998-07-31
NAID 10008085511