WordNet
- the 16th letter of the Roman alphabet (同)p
- matter that remains after something has been removed
PrepTutorEJDIC
- parking
- phosphorusの化学記号
- 残り,残余;残留物
UpToDate Contents
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- 1. インスリン受容体の構造および機能 structure and function of the insulin receptor
- 2. 成人におけるS状結腸鏡検査および大腸内視鏡検査のための前処置 bowel preparation for colonoscopy and flexible sigmoidoscopy in adults
- 3. 鎌状ヘモグロビン多量体：構造と機能特性 sickle hemoglobin polymer structure and functional properties
- 4. 直腸腟瘻、肛門腟瘻、および結腸膀胱瘻 rectovaginal anovaginal and colovesical fistulas
- 5. ガストリンの生理学 physiology of gastrin
English Journal
- Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells.
- Bourguet CB1, Boulay PL2, Claing A2, Lubell WD3.
- Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2014 Aug 1;24(15):3361-5. doi: 10.1016/j.bmcl.2014.05.095. Epub 2014 Jun 14.
- A set of azapeptides was designed based on the Ala-Val-Pro-Ile peptide (derived from Smac protein) to activate caspase-9 and induce apoptosis in breast cancer cells. The diversity-oriented synthesis of the aza-peptides 5-9 was accomplished by alkylation of the aza-residue of aza-Gly-Pro dipeptide 15
- PMID 24986663
- Identification of Functionally Important Residues of the Silkmoth Pheromone Biosynthesis-activating Neuropeptide Receptor, an Insect Ortholog of the Vertebrate Neuromedin U Receptor.
- Kawai T1, Katayama Y1, Guo L1, Liu D1, Suzuki T1, Hayakawa K1, Lee JM2, Nagamine T2, Hull JJ3, Matsumoto S2, Nagasawa H1, Tanokura M4, Nagata K5.
- The Journal of biological chemistry.J Biol Chem.2014 Jul 4;289(27):19150-19163. Epub 2014 May 20.
- The biosynthesis of sex pheromone components in many lepidopteran insects is regulated by the interaction between pheromone biosynthesis-activating neuropeptide (PBAN) and the PBAN receptor (PBANR), a class A G-protein-coupled receptor. To identify functionally important amino acid residues in the s
- PMID 24847080
- Lead Optimization of P5U and Urantide: Discovery of Novel Potent Ligands at Urotensin-II Receptor.
- Carotenuto A, Auriemma L, Merlino F, Yousif AM, Marasco D, Limatola A, Campiglia P, Gomez-Monterrey I, Santicioli P, Meini S, Maggi CA, Novellino E, Grieco P.
- Journal of medicinal chemistry.J Med Chem.2014 Jul 3. [Epub ahead of print]
- We have optimized 1 (P5U) and urantide, two important ligands at the h-UT receptor, designing several analogues by the exchange of the Tyr9 residue with different unnatural aromatic amino acids. This study allowed us to discover novel ligands with improved activity. In particular, the replacement of
- PMID 24992374
Japanese Journal
- Analysis of amino acid residues involved in cold activity of monomeric isocitrate dehydrogenase from psychrophilic bacteria, Colwellia maris and Colwellia psychrerythraea
- Yasuda Wataru,Kobayashi Miyuki,Takada Yasuhiro
- Journal of bioscience and bioengineering 116(5), 567-572, 2013-11
- … In the C-terminal region 3 of these enzymes, which was suggested from previous study to be responsible for their distinct catalytic ability, several sequential differences of amino acid residue are present. … The mutated enzymes of CmIDH-II substituted its Gln671, Leu724 and Phe735 residues with the corresponding residues of CpIDH-M (termed Q671K, L724Q and F735L, respectively) showed lower specific activity and thermostability for activity than the wild-type enzyme. …
- NAID 120005372325
- Analysis of amino acid residues involved in cold activity of monomeric isocitrate dehydrogenase from psychrophilic bacteria, Colwellia maris and Colwellia psychrerythraea(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Yasuda Wataru,Kobayashi Miyuki,Takada Yasuhiro
- Journal of bioscience and bioengineering 116(5), 567-572, 2013-11
- … In the C-terminal region 3 of these enzymes, which was suggested from previous study to be responsible for their distinct catalytic ability, several sequential differences of amino acid residue are present. … The mutated enzymes of CmIDH-II substituted its Gln671, Leu724 and Phe735 residues with the corresponding residues of CpIDH-M (termed Q671K, L724Q and F735L, respectively) showed lower specific activity and thermostability for activity than the wild-type enzyme. …
- NAID 110009685205
- Two arginine residues in the substrate pocket predominantly control the substrate selectivity of thiocyanate hydrolase(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Yamanaka Yasuaki,Arakawa Takatoshi,Watanabe Toshinori,Namima Satoshi,Sato Masa,Hori Shota,Ohtaki Akashi,Noguchi Keiichi,Katayama Yoko,Yohda Masafumi,Odaka Masafumi
- Journal of bioscience and bioengineering 116(1), 22-27, 2013-07
- … Based on the differences in the substrate-binding pockets of these enzymes, βArg90 and γArg136 of SCNase, with side chains extending toward the pocket, were separately substituted with Phe and Trp, the corresponding residues, respectively, in Co-type NHase. … the size of the substrate pocket was enlarged because of conformational changes on the side chains of the mutated residue. …
- NAID 110009634740
Related Links
- ... “Dermorphin and deltorphin heptapeptide analogues: replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity,” Bioorganic and Medicinal Chemistry Letters, vol. 12, no. 6, pp. 879–881, 2002. · ...
- The unique residue Phe 25 distinguishes the interfacial core of 14-3-3σ from other 14-3-3 isoforms in two aspects. First, Phe 25 forms the unique aromatic pair with the conserved residue Tyr 84. Second, Phe 25 forces Lys 9 3 25 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「フェニルアラニン残基」「Phe残基」「phenylalanine residue」 |
| 関連記事 | 「Ph」「P」「residue」「Phe」 |
「フェニルアラニン残基」
「Phe残基」
「phenylalanine residue」
「Ph」
「P」
「residue」
- 関
- residual
「Phe」
- 同
- フェニルアラニン
- 同
- フェニルアラニン