- 英
- (n
- 関
- ホスホリパーゼCγ、ホスホリパーゼC-γ、PLCγ
WordNet
- the 16th letter of the Roman alphabet (同)p
PrepTutorEJDIC
- parking
- phosphorusの化学記号
UpToDate Contents
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Japanese Journal
- Inhibitory Effects of BST406, a Newly Synthesized Benzylideneacetophenone Derivative, on Abnormal Vascular Smooth Muscle Cell Proliferation
- Kim Tack-Joong,Han Hyeong-Jun,Kim Yong-Jae [他],Jung Jae-Chul,Yu Ji-Yeon,Lee Jung-Jin,Yun Yeo-Pyo
- Biological and Pharmaceutical Bulletin 33(5), 900-904, 2010
- … In Western blot analysis, PDGF-BB-stimulated (25 ng/ml) phospholipase-C (PLC)γ1 and Akt phosphorylation was inhibited by BST406 (0—10μM). … To confirm that the inhibitory effects of BST406 are mediated through the inhibition of PLCγ1 or Akt, the effects of inhibitors on cell viability were examined. … These findings suggest that the inhibitory effects of BST406 on the proliferation of PDGF-BB-stimulated VSMCs are mediated by suppression of the PLCγ1 signaling pathways. …
- NAID 130000248056
- チロシンリン酸化による糸球体上皮細胞(ポドサイト)機能の制御
- 服部 成介
- 日本小児腎臓病学会雑誌 = Japanese journal of pediatric nephrology 22(2), 152-160, 2009-11-15
- … Nephrinには既知のNckの他にさまざまな因子が結合し,PLC-γを介して細胞内カルシウムの調節を行う。 … PLC-γはTRPC6チャネルを活性化するのに対し,NephrinはTRPC6に対して抑制的であるが,家族性巣状糸球体硬化症でみられるTRPC6変異はNephrinによる制御から逸脱していた。 …
- NAID 10026411853
- Corynoxeine Isolated from the Hook of Uncaria rhynchophylla Inhibits Rat Aortic Vascular Smooth Muscle Cell Proliferation through the Blocking of Extracellular Signal Regulated Kinase 1/2 Phosphorylation(Pharmacology)
- Kim Tack-Joong,Lee Ju-Hyun,Lee Jung-Jin [他],YU Ji-Yeon,HWANC Bang-Yeon,YE Sang-Kyu,SHUJUAN Li,GAO Li,PYO Myoung-Yun,YUN Yeo-Pyo
- Biological & pharmaceutical bulletin 31(11), 2073-2078, 2008-11-01
- … Pre-incubation of VSMCs with corynoxeine significantly inhibited PDGF-BB-induced extracellular signal-regulated kinase 1/2 (ERK1/2) activation, whereas corynoxeine had no effects on mitogen-activated protein kinase (MAPK/ERK)-activating kinase 1 and 2 (MEK1/2), Akt, or phospholipase C (PLC) γ1 activation or on PDGF receptor beta (PDGF-Rβ) phosphorylation. …
- NAID 110006968090
Related Links
- 神戸大学大学院医学研究科 生化学分野 高野令名 はじめに ホスホリパーゼC(PLC)はイノシトールリン脂質代謝においてセカンドメッセンジャー産生のエフェクター因子となる酵素である。活性化されたPLCは ...
- ... (DEX, a synthetic glucocorticoid) suppressed BDNF-induced glutamate release via weakening the activation of the PLC-γ (phospholipase C-γ)/Ca 2+ system in cultured cortical neurons. We demonstrated that the GR Abstract ...
Related Pictures
![on the Phosphorylation of PLC γ 2 and p47](https://1mg.info/0/f/u/0655.jpg)
![STAT proteins Grb2 GAP SH2 PLC γ](https://1mg.info/0/f/u/0656.jpg)
![plc γ 2 and pkc activation washed](https://1mg.info/0/f/u/0657.jpg)
![PLC γ 1 activation downstream of FGFR2](https://1mg.info/0/f/u/0658.jpg)
![plc γ 2 and pkc activation washed](https://1mg.info/0/f/u/0659.jpg)
★リンクテーブル★
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- 英
- (n
- 関
- ホスホリパーゼCγ、ホスホリパーゼC-γ、PLC-γ
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- 英
- phospholipase C gamma、PLC-gamma
- 関
- ホスホリパーゼC-γ、PLCγ、PLC-γ
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- PL配合顆粒
- 総合感冒剤/鎮咳,抗ヒスタミン,解熱配合剤/総合感冒剤
参考
http://www.interq.or.jp/ox/dwm/se/se11/se1180107.html
http://www.info.pmda.go.jp/go/pack/1180107D1131_1_02/
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