- 英
- NHE
- 同
- Na2+/H+交換輸送体
WordNet
- hand over one and receive another, approximately equivalent; "exchange prisoners"; "exchange employees between branches of the company"
- chemical process in which one atom or ion or group changes places with another
- reciprocal transfer of equivalent sums of money (especially the currencies of different countries); "he earns his living from the interchange of currency" (同)interchange
- the act of changing one thing for another thing; "Adam was promised immortality in exchange for his disobedience"; "there was an interchange of prisoners" (同)interchange
- (chess) gaining (or losing) a rook in return for a knight or bishop; "black lost the exchange"
- (chess) the capture by both players (usually on consecutive moves) of pieces of equal value; "the endgame began after the exchange of queens"
- a workplace for buying and selling; open only to members
- the act of giving something in return for something received; "deductible losses on sales or exchanges of property are allowable"
- a mutual expression of views (especially an unpleasant one); "they had a bitter exchange"
- give to, and receive from, one another; "Would you change places with me?"; "We have been exchanging letters for a year" (同)change, interchange
- the 8th letter of the Roman alphabet (同)h
- one whose business is to exchange the money of one country for that of another country (同)money changer
- the 14th letter of the Roman alphabet (同)n
PrepTutorEJDIC
- …‘を'『取り替える』;(…と)…‘を'取り替える《+『名』+『for』+『名』》 / …‘を'『取り交わす』;(人と)…‘を'取り交わす《+『名』+『with』+『名』〈人〉》 / (化幣が)両替される / 〈U〉〈C〉(物の物との)『取り替え』《+『of』+『名』+『for』+『名』》;(相手と物を)『交換すること』《+『of』+『名』(複数)+『with』+『名』〈人〉》 / 〈C〉交換物,取り替え品 / 〈C〉取引所;(電話の)交換局 / 〈U〉両替;為替(かわせ),為替相場 / 〈C〉=employment exchange
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
- nitrogenの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/17 06:08:18」(JST)
[Wiki en表示]
The sodium–hydrogen antiporter or sodium–hydrogen exchanger is a membrane protein found in many cells, and especially in those of the nephron of the kidney. Specifically in the intercalary cells of the collecting duct. The membrane pump is primarily responsible for maintaining the balance of pH.[1]
Isoforms
There are several isoforms of the antiporter:
- Sodium–hydrogen antiporter 1
- Sodium–hydrogen antiporter 2
- Sodium–hydrogen antiporter 3
- Sodium–hydrogen antiporter 5
- Sodium–hydrogen antiporter 6
- Sodium–hydrogen antiporter 8
References
- ^ [1]
External links
- Sodium-Hydrogen Exchanger at the US National Library of Medicine Medical Subject Headings (MeSH)
Membrane transport protein: ion pumps, ATPases / ATP synthase (TC 3A2-3A3)
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F-, V-, and A-type ATPase (3.A.2) |
H+ (F-type)
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- H+ transporting, mitochondrial: ATP5A1
- ATP5B
- ATP5C1
- ATP5C2
- ATP5D
- ATP5E
- ATP5F1
- ATP5G1
- ATP5G2
- ATP5G3
- ATP5H
- ATP5I
- ATP5J
- ATP5J2
- ATP5L
- ATP5L2
- ATP5O
- ATP5S
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H+ (V-type)
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- H+ transporting, lysosomal: ATP6AP1
- ATP6AP2
- ATP6V1A
- ATP6V1B1
- ATP6V1B2
- ATP6V1C1
- ATP6V1C2
- ATP6V1D
- ATP6V1E1
- ATP6V1E2
- ATP6V1F
- ATP6V1G1
- ATP6V1G2
- ATP6V1G3
- ATP6V1H
- ATP6V0A1
- ATP6V0A2
- ATP6V0A4
- ATP6V0B
- ATP6V0C
- ATP6V0D1
- ATP6V0D2
- ATP6V0E
- ATP6V0E1
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A-ATPase
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found in Archea
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P-type ATPase (3.A.3) |
- 3.A.3.1.1: Na+/K+ transporting: ATP1A1
- ATP1A2
- ATP1A3
- ATP1A4
- ATP1B1
- ATP1B2
- ATP1B3
- ATP1B4
- ATP1G1
- 3.A.3.1.2: H+/K+
- H+/K+ exchanging: ATP4A
- ATP4B
- 3.A.3.1.4: H+/K+ transporting, nongastric: ATP12A
- 3.A.3.2: Ca+ (SERCA, PMCA, SPCA) / Ca++ transporting: ATP2A1
- ATP2A2
- ATP2A3
- ATP2B1
- ATP2B2
- ATP2B3
- ATP2B4
- ATP2C1
- 3.A.3.5: Cu++ transporting: ATP7A
- ATP7B
- 3.A.3.8.8: flippase: ATP8A2
- Mg++ transporting: ATP3
- Class I, type 8: ATP8A1
- ATP8B1
- ATP8B2
- ATP8B3
- ATP8B4
- Class II, type 9: ATP9A
- ATP9B
- Class V, type 10: ATP10A
- ATP10B
- ATP10D
- Class VI, type 11: ATP11A
- ATP11B
- ATP11C
- type 13: ATP13A1
- ATP13A2
- ATP13A3
- ATP13A4
- ATP13A5
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see also ATPase disorders
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UpToDate Contents
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English Journal
- Ammonia and urea excretion in the swimming crab Portunus trituberculatus exposed to elevated ambient ammonia-N.
- Ren Q1, Pan L2, Zhao Q1, Si L1.
- Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.Comp Biochem Physiol A Mol Integr Physiol.2015 Sep;187:48-54. doi: 10.1016/j.cbpa.2015.04.013. Epub 2015 May 3.
- In the present study of the swimming crab Portunus trituberculatus exposed to 0, 1, and 5mgL(-1) NH4Cl, the effects of ammonia exposure on ammonia and urea content in hemolymph; activity of H(+)-ATPase (subunit A) and Na(+)/K(+)-ATPase (α-subunit) (NKA) in gills; mRNA expression levels of the crust
- PMID 25946713
- Implications of sodium hydrogen exchangers in various brain diseases.
- Verma V, Bali A, Singh N, Jaggi AS.
- Journal of basic and clinical physiology and pharmacology.J Basic Clin Physiol Pharmacol.2015 Sep 1;26(5):417-26. doi: 10.1515/jbcpp-2014-0117.
- Na+/H+ exchangers (NHEs) are the transporter proteins that play an important role in intracellular pH (pHi) regulation, cell differentiation and cell volume and that mediate transepithelial Na+ and HCO3- absorption on the basis of chemical gradients across the plasma membrane. Its activation causes
- PMID 26020555
- Targeting osteopontin, the silent partner of Na+/H+ exchanger isoform 1 in cardiac remodeling.
- Mohamed IA1, Mraiche F1.
- Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2006-18. doi: 10.1002/jcp.24958.
- Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, contributes to cardiac remodeling, which if left unresolved results in heart failure. Understanding the signaling pathways underlying CH is necessary to identify potential therapeutic targets. The N
- PMID 25677682
Japanese Journal
- Production of Reactive Oxygen Species in the Diabetic Heart:– Roles of Mitochondria and NADPH Oxidase –
- Teshima Yasushi,Takahashi Naohiko,Nishio Satoru,Saito Shotaro,Kondo Hidekazu,Fukui Akira,Aoki Kouhei,Yufu Kunio,Nakagawa Mikiko,Saikawa Tetsunori
- Circulation Journal 78(2), 300-306, 2014
- … Increased intracellular calcium level mediated via the Na+-H+ exchanger and subsequent activation of Ca2+/calmodulin-dependent protein kinase II may also activate NADPH oxidase. …
- NAID 130003382238
- Roles of Na^+/H^+ Exchanger Type 1 and Intracellular pH in Angiotensin II-Induced Reactive Oxygen Species Generation and Podocyte Apoptosis
- LIU Ya,HITOMI Hirofumi,DIAH Suwarni,DEGUCHI Kazushi,MORI Hirohito,MASAKI Tsutomu,NAKANO Daisuke,KOBORI Hiroyuki,NISHIYAMA Akira
- Journal of pharmacological sciences 122(3), 176-183, 2013-07-20
- NAID 10031185411
- Roles of Na⁺/H⁺ Exchanger Type 1 and Intracellular pH in Angiotensin Ⅱ-Induced Reactive Oxygen Species Generation and Podocyte Apoptosis
- Liu Ya,Hitomi Hirofumi,Diah Suwarni [他],Deguchi Kazushi,Mori Hirohito,Masaki Tsutomu,Nakano Daisuke,Kobori Hiroyuki,Nishiyama Akira
- Journal of Pharmacological Sciences 122(3), 176-183, 2013
- … Pre-treatment with olmesartan (100 nmol/L, an Ang II type 1–receptor blocker), apocynin (50 μmol/L, NADPH oxidase inhibitor), or 5-N,N hexamethylene amiloride [30 μmol/L, Na+/H+ exchanger type 1 (NHE-1) inhibitor] abolished Ang II–induced podocyte apoptosis, whereas NHE-1 mRNA and protein expression was not affected by Ang II treatment. …
- NAID 130003362720
Related Links
- Supporting information and details of available scientific literature for Na+/H+ Exchanger ... Na + /H + Exchanger Supporting information Sodium-hydrogen exchangers (Na + /H + exchangers, NHE) are ATP-independent membrane ...
- 1. Eur J Med Chem. 2003 Jun;38(6):547-54. An overview of inhibitors of Na(+)/H(+) exchanger. Masereel B(1), Pochet L, Laeckmann D. Author information: (1)Department of Pharmacy, University of Namur, 61 ...
★リンクテーブル★
[★]
[★]
- 関
- interchange、replace、replacement、swap
[★]
交換体、交換輸送体、エクスチェンジャー
- 関
- antiporter、translocase
[★]
[★]