MAOB inhibitors

関

Monoamine oxidase B inhibitors

WordNet

1. a substance that retards or stops an activity

PrepTutorEJDIC

1. 抑制する人(物) / 化学反応抑制剤
2. Massachusetts / mental age

UpToDate Contents

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• 1. 血管新生阻害剤の概要 overview of angiogenesis inhibitors
• 2. 進行腎明細胞癌または転移性腎明細胞癌に対する抗血管新生療法および分子標的療法 anti angiogenic and molecularly targeted therapy for advanced or metastatic clear cell renal cell carcinoma
• 3. 成人におけるうつ病治療としてのモノアミン酸化酵素阻害剤（MAOI） monoamine oxidase inhibitors maois for treating depressed adults
• 4. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation
• 5. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia

English Journal

• Different generations of type-B monoamine oxidase inhibitors in Parkinson's disease: from bench to bedside.

• Alborghetti M1, Nicoletti F1.
• Current neuropharmacology.Curr Neuropharmacol.2018 Aug 29. doi: 10.2174/1570159X16666180830100754. [Epub ahead of print]
• PMID 30160213

• Real life evaluation of safinamide effectiveness in Parkinson's disease.

• Mancini F1, Di Fonzo A2, Lazzeri G2, Borellini L3, Silani V4,5, Lacerenza M6, Comi C7.
• Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology.Neurol Sci.2018 Apr;39(4):733-739. doi: 10.1007/s10072-018-3272-y. Epub 2018 Feb 13.
• PMID 29441484

• Monoamine oxidase-B inhibitor protects degenerating spinal neurons, enhances nerve regeneration and functional recovery in sciatic nerve crush injury model.

• Hussain AM1, Renno WM2, Sadek HL1, Kayali NM1, Al-Salem A1, Rao MS1, Khan KM1.
• Neuropharmacology.Neuropharmacology.2018 Jan;128:231-243. doi: 10.1016/j.neuropharm.2017.10.020. Epub 2017 Oct 17.
• PMID 29054367

Japanese Journal

• MAOB阻害薬 (特集 パーキンソン病の基礎と臨床の最先端) -- (パーキンソン病新薬紹介)

• 脳21 19(4), 398-401, 2016
• NAID 40021018661

• Catechol-O-methyltransferase and Parkinson's disease.

• Acta Medica Okayama 56(1), 1-6, 2002-02
• NAID 120002312366

Related Links

• MAO-B Inhibitors | National Parkinson Foundation

What Are the Side Effects? The most common side effects of MAO-B inhibitors include the following: Mild nausea Dry mouth Lightheadedness Constipation Confusion (can occur in the elderly person with PD) Hallucinations (can ...

• Parkinson's UK - MAO-B inhibitors

MAO-B inhibitors are used to treat the symptoms of Parkinson's. These drugs are mainly available as tablets. There is also a form that dissolves on the tongue. They prevent the breakdown of the chemical messenger dopamine in the ...

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★リンクテーブル★

関連記事	「MAOB」「inhibitor」「MA」「MAO」

「MAOB」

　　[★]

同

monoamine oxidase B,MAO-B

関

モノアミンオキシダーゼ

• 神経細胞内のミトコンドリア外膜に局在 (SPC.67)
• カテコラミンを酸化的脱アミノ化する (SPC.67)
• ２つのisoformが存在するが、MAO_Bは、ドパミン、チラミンを特異的な基質とする (SPC.67)

「inhibitor」

　　[★]

• n.

• 阻害剤、阻害薬、抑制薬、抑制剤、(内在性物質について)インヒビター、抑制物質

関

blocker、depressant、suppressant

　 　

「MA」

　　[★]

• 僧帽弁閉鎖症 僧帽弁閉鎖 mitral atresia
• 僧帽弁輪 mitral annulus

　

「MAO」

　　[★] モノアミンオキシダーゼ monoamine oxidase