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1. 先天性性腺刺激ホルモン放出ホルモン欠乏症（特発性低ゴナドトロピン性性腺機能低下） congenital gonadotropin releasing hormone deficiency idiopathic hypogonadotropic hypogonadism
2. 性腺刺激ホルモン（ゴナドトロピン）放出ホルモンの生理学 physiology of gonadotropin releasing hormone
3. アンドロゲン過剰症および男性型多毛症治療におけるGnRHアゴニストの使用 use of gnrh agonists in the treatment of hyperandrogenism and hirsutism
4. Endometriosis: Long-term treatment with gonadotropin-releasing hormone agonists
5. 転移性ホルモン受容体陽性乳癌に対する治療アプローチ：内分泌療法 treatment approach to metastatic hormone receptor positive breast cancer endocrine therapy

English Journal

Pharmacologic profiles of investigational kisspeptin/metastin analogues, TAK-448 and TAK-683, in adult male rats in comparison to the GnRH analogue leuprolide.

Matsui H1, Masaki T2, Akinaga Y2, Kiba A2, Takatsu Y2, Nakata D2, Tanaka A2, Ban J3, Matsumoto S2, Kumano S2, Suzuki A2, Ikeda Y3, Yamaguchi M2, Watanabe T2, Ohtaki T2, Kusaka M3.
European journal of pharmacology.Eur J Pharmacol.2014 Jul 15;735:77-85. doi: 10.1016/j.ejphar.2014.03.058. Epub 2014 Apr 18.
Kisspeptin/metastin, a hypothalamic peptide, plays a pivotal role in controlling gonadotropin-releasing hormone (GnRH) neurons, and we have shown that continuous subcutaneous administration of kisspeptin analogues suppresses plasma testosterone in male rats. This study examined pharmacologic profile
PMID 24747751

Ovarian stripping versus cystectomy: recurrence of endometriosis and pregnancy rate.

Moscarini M1, Milazzo GN, Assorgi C, Pacchiarotti A, Caserta D.
Archives of gynecology and obstetrics.Arch Gynecol Obstet.2014 Jul;290(1):163-7. doi: 10.1007/s00404-014-3158-z. Epub 2014 Feb 1.
PURPOSE: To compare two different surgical techniques, stripping or cystectomy, in patients treated with the same post-operative medical therapy in terms of recurrence of endometrioma, recurrence of pain and spontaneous pregnancy rate within 2 years from surgery.METHODS: The inclusion criteria of t
PMID 24488581

Design and synthesis of fluorescent probes for GPR54.

Kaneda M1, Misu R1, Ohno H1, Hirasawa A1, Ieda N2, Uenoyama Y2, Tsukamura H2, Maeda K3, Oishi S4, Fujii N5.
Bioorganic & medicinal chemistry.Bioorg Med Chem.2014 Jul 1;22(13):3325-30. doi: 10.1016/j.bmc.2014.04.052. Epub 2014 May 5.
Kisspeptins are neuropeptides that induce the secretion of gonadotropin-releasing hormone via the activation of the cognate receptor, G-protein coupled receptor 54 (GPR54). The kisspeptin-GPR54 axis is associated with the onset of puberty and the maintenance of the reproductive system. In this study
PMID 24857775

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