関: E2F-1 protein、E2F-1 transcription factor、E2F1、transcription factor E2F-1、transcription factor E2F1

WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
(genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
a sound or television recording (e.g., from a broadcast to a tape recording)
something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)

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Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures.

Wang Y1, Alla V1, Goody D1, Gupta SK2, Spitschak A1, Wolkenhauer O2, Pützer BM3, Engelmann D1.
Nucleic acids research.Nucleic Acids Res.2015 Sep 8. pii: gkv885. [Epub ahead of print]
Transcription factor E2F1 is a key regulator of cell proliferation and apoptosis. Recently, it has been shown that aberrant E2F1 expression often detectable in advanced cancers contributes essentially to cancer cell propagation and characterizes the aggressive potential of a tumor. Conceptually, thi
PMID 26350215

Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene.

Tsai YT1, Chang CM1, Wang JY2,3,4, Hou MF2,3,4,5, Wang JM6,7, Shiurba R8, Chang WC7, Chang WC1,2,9,10.
Environmental toxicology.Environ Toxicol.2015 Sep;30(9):1024-32. doi: 10.1002/tox.21976. Epub 2014 Mar 17.
Lead ions (Pb(2+) ) are toxic industrial pollutants associated with chronic inflammatory diseases in humans and animals. Previously, we found that Pb(2+) ions induce COX-2 gene expression via the EGF receptor/nuclear factor-κB signal transduction pathway in epidermoid carcinoma cell line A431. In t
PMID 24639330

Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts.

Kitamura H1, Ozono E2, Iwanaga R3, Bradford AP3, Okuno J1, Shimizu E1, Kurayoshi K1, Kugawa K1, Toh H1, Ohtani K1.
Genes to cells : devoted to molecular & cellular mechanisms.Genes Cells.2015 Sep;20(9):739-757. doi: 10.1111/gtc.12268. Epub 2015 Jul 23.
The transcription factor E2F is the principal target of the tumor suppressor pRB. E2F plays crucial roles not only in cell proliferation by activating growth-related genes but also in tumor suppression by activating pro-apoptotic and growth-suppressive genes. We previously reported that, in human no
PMID 26201719

Aryl Hydrocarbon Receptor Functions as a Potent Coactivator of E2F1-Dependent Trascription Activity

Watabe Yuichi,Nazuka Noriaki,Tezuka Masakatsu [他],Shimba Shigeki
Biological and Pharmaceutical Bulletin 33(3), 389-397, 2010
… The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates a spectrum of toxic and biological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. … Expression of these genes is mainly regulated by E2F1, a transcription factor that is crucial for transition of the cell cycle from G1 to S phase. …
NAID 130000248087

Takaya Tomoyuki,Kasatani Kaori,Noguchi Syunsuke [他],NIKAWA Jun-ichi
Bioscience, biotechnology, and biochemistry 73(7), 1653-1660, 2009-07-23
… We obtained two types of cDNA, E2F1, known as a gene encoding Rb-binding protein, and ETR101. … The E2F1 … gene product (E2F1) is known to bind to and activate the ISYNA1 … In a manner similar to E2F1, ETR101 binds to and activates the ISYNA1 …
NAID 10027543865