WordNet

the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/03 18:37:28」(JST)

Design, synthesis and biological evaluation of inhibitors of cathepsin K on dedifferentiated chondrocytes.

Yuan XY, Ren Z, Wu Y, Bougault C, Brizuela L, Magne D, Buchet R, Mebarek S.
Bioorganic & medicinal chemistry. 2019 Mar;27(6)1034-1042.
Selective proteinase inhibitors have demonstrated utility in the investigation of cartilage degeneration mechanisms and may have clinical use in the management of osteoarthritis. The cysteine protease cathepsin K (CatK) is an attractive target for arthritis therapy. Here we report the synthesis of t
PMID 30773420

ZmSMR4, a novel cyclin-dependent kinase inhibitor (CKI) gene in maize (Zea mays L.), functions as a key player in plant growth, development and tolerance to abiotic stress.

Li F, Wang L, Zhang Z, Li T, Feng J, Xu S, Zhang R, Guo D, Xue J.
Plant science : an international journal of experimental plant biology. 2019 Mar;280()120-131.
Endoreduplication is a key cell cycle variant in the developing maize endosperm and has been associated with cell enlargement and dry matter accumulation. Therefore, identification of the key genes associated with endosperm development and endoreduplication would not only lay the groundwork for unde
PMID 30823990

Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Iα and δ.

Lee JW, Hirota T, Ono D, Honma S, Honma KI, Park K, Kay SA.
Journal of medicinal chemistry. 2019 Feb;62(4)1989-1998.
Circadian rhythms are controlled by transcriptional feedback loops of clock genes and proteins. The stability of clock proteins is regulated by post-translational modification, such as phosphorylation by kinases. In particular, casein kinase I (CKI) phosphorylates the PER protein to regulate proteas
PMID 30707835