英: embryonal blood formation

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1. 造血幹細胞の概要overview of hematopoietic stem cells [show details]
… maintain long-term multilineage hematopoiesis throughout the lifespan of an individual. The concept that sustained hematopoiesis comes from multipotent stem cells… E10.5 transition to the fetal liver after the circulation is established. The progeny of the EMPs support fetal erythropoiesis,…
2. 未確定の潜在能をもつクローン性造血（CHIP）とクローン性造血の関連疾患clonal hematopoiesis of indeterminate potential chip and related disorders of clonal hematopoiesis [show details]
…Categories of CH include: Clonal hematopoiesis of indeterminate potential (CHIP) Clonal cytopenia of undetermined significance (CCUS) Aging-related clonal hematopoiesis (ARCH) CHIP, CCUS, and ARCH are …
3. 胎盤の病理：神経学的障害児に関連可能な所見placental pathology findings potentially associated with neurologic impairment in children [show details]
…insufficiency and fetal hypoxia. In theory, these adaptations could improve placental function, but there is no evidence that they do so. Exposure of the bone marrow and other sites of fetal hematopoiesis (eg, liver) …
4. 死産：母胎と胎児の評価stillbirth maternal and fetal evaluation [show details]
…villous vessels luminal abnormalities) and fetal organs (eg, loss of nuclear basophilia) have also been correlated with time of fetal death . The development of fetal organ changes is affected by factors such …
5. 健常者および患者における胎児性ヘモグロビン（ヘモグロビンF）fetal hemoglobin hemoglobin f in health and disease [show details]
… not resemble fetal erythrocytes, except for their high levels of HbF . F cells are typical adult erythrocytes with adult MCV of approximately 80 fL, in contrast to fetal erythrocytes,… The MYB transcription factor is a key regulator of hematopoiesis and erythropoiesis ,…

Japanese Journal

マウス胎生期における造血幹細胞の発生と造血幹細胞非依存性造血

吉本桃子
臨床血液 59(7), 915-921, 2018
… 本稿は胎生期造血の概要を述べるとともに，造血幹細胞の発生および，造血幹細胞非依存性造血について紹介する。 …
NAID 130007430587

胎生期造血ニッチによる赤血球造血制御とその臨床応用検討

杉山大介,田中由香,湯岑綾子,小島直子
臨床血液 57(7), 944-950, 2016
<p>赤血球造血には，一次造血と二次造血の二つの波がある。マウス胎仔の二次造血は卵黄嚢で始まり，肝臓，脾臓，骨髄へと移行する。胎仔肝臓は，赤血球系細胞増殖・成熟が起こる主要臓器であり，SCF, TPO, IGF2等を発現するニッチ細胞の解析が活発に行われてきた。以前我々は，DLK1陽性肝芽細胞がEPO, SCF, 細胞外マトリックスを発現して胎仔肝臓造血に寄与することを報告した。肝芽細 …
NAID 130005254950