英: time, dose and fractionation factor, TDF factor TDF因子
関: 時間-線量関係

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1. 成人の潰瘍性大腸炎治療に用いる生物学的製剤や低分子医薬品の用量およびモニタリングの概要overview of dosing and monitoring of biologic agents and small molecules for treating ulcerative colitis in adults [show details]
… response while on maintenance dosing and who are candidates for dose escalation, options include increasing the maintenance dose to 100 mg every four weeks,… disease). For patients with evidence of immunity who are ≥50 years old, we assess the need for and timing of zoster (shingles) vaccination, and this is discussed separately. For patients without evidence …
2. 高齢女性における卵巣癌に対するアプローチthe approach to ovarian cancer in older women [show details]
… appropriate first-line treatment for ovarian cancer. For older adult patients, chemotherapy dosing, scheduling, and timing (neoadjuvant or postoperative) should be carefully considered when developing a treatment …
3. 免疫グロブリン静脈内投与（IVIG）療法の概要overview of intravenous immune globulin ivig therapy [show details]
… Compared with subcutaneous dosing given more frequently, bolus IV dosing yields lower serum levels of IgG at the end of each dosing interval as the time for the next dose nears. Some patients will become …
4. 小児や青年への定期予防接種：概要standard immunizations for children and adolescents overview [show details]
… trials suggested that the acetaminophen dose given around the time of vaccination is more important than doses administered >4 hours after immunization . Invalid doses need to be repeated because they may …
5. 成人の炎症性腸疾患患者へのブデソニド療法の概要overview of budesonide therapy for adults with inflammatory bowel disease [show details]
…systemic bioavailability of the drug is decreased. This topic will review the pharmacology, indications, dosing, and safety of budesonide in the management of chronic, inflammatory bowel disease (IBD). The efficacy … and they include : Ileal release formulations: Controlled ileal release formulation (CIR, pH- and time-dependent release) – The controlled ileal release formulation is a gelatin capsule filled with enteric …