β-ラクタム化合物
WordNet
- create by mixing or combining
- (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight (同)chemical_compound
- put or add together; "combine resources" (同)combine
- an enclosure of residences and other building (especially in the Orient)
- a whole formed by a union of two or more elements or parts
- combine so as to form a whole; mix; "compound the ingredients" (同)combine
- calculate principal and interest
- composed of more than one part; "compound leaves are composed of several lobes; "compound flower heads"
- consisting of two or more substances or ingredients or elements or parts; "soap is a compound substance"; "housetop is a compound word"; "a blackberry is a compound fruit"
- combined into or constituting a chemical compound
PrepTutorEJDIC
- (…になるように)〈要素・成分など〉'を'混ぜ合わせる《+『名』+『into』+『名』》;(…から)〈薬など〉'を'調合する,混ぜ合わせて作る《+『名』+『from』(『of』)+『名』》 / 《しばしば受動態で》〈めんどうな事・損害など〉'を'もっとひどくする / 〈利子〉'を'複利で計算する / (…と)話し合いをつける,妥協する《+『with』+『名』》 / 複合の,合成の / 『合成物』,混合物,調合物;化合物 / 複合語,合成語(classroom, heart-to-heartなどをいう)
- (異民族の家屋・商館などがある)囲み地区,構内
UpToDate Contents
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Japanese Journal
- 供田 洋
- 薬学雑誌. 乙号 132(1), 37-44, 2012
- … Our computational modeling experiments indicated that spirohexaline A was inserted into the substrate pocket of UPP synthase and interacted with Glu88 via a carbamoyl group of the compound, with Ala76, Met54 and Asn35 via three hydroxyl groups, and with certain hydrophobic amino acids via a spiro ring. … K04-0144, was isolated as a potentiator of β-lactam imipenem activity against MRSA. … The compound consisted of a labdan skeleton and an N-acetylcysteine. …
- NAID 130001871960
- 高分子を用いた消化管腔内環境の制御とPEPT1介在性膜輸送
- 玉井 郁巳
- 膜 36(4), 163-170, 2011-07-01
- … Since substrates of PEPT1 exhibits varible optimal pH depending on substrates, acidic polymer Eudragit L100-55 (EL) was employed to control intestinal luminal pH to be optimal for low permerble PEPT1 substrate, β-lactam antibiotic cefiximie which exhibits optimal transport by PEPT1 at pH 5 or lower, as model compound. …
- NAID 10029602065
- α,β-不飽和イミンへの共役付加反応を用いる新規合成反応
- 八谷 巌,清水 真
- 有機合成化学協会誌 68(10), 1006-1016, 2010-10-01
- … The development of a new efficient synthetic method of nitrogen containing compounds is extensively studied because there are many nitrogen containing compounds such as amino acids, alkaloids, and β-lactams having biological activities and functionalized materials for organic electronics or photonics. …
- NAID 10026870954
Related Links
- BACKGROUND OF THE INVENTION The present invention relates to a β-lactam compound wherein a specific acyl group, etc., are substituted for a hydrogen atom of the amino group of the 2-aminoacetamido group of a ...
- Description β-lactam is an important medical compound since it is used as a backbone of the anti-bacterial agents and a precursor of amino acids. Especially, β-lactam containing a chiral carbon is used for the synthesis of peptide ...
★リンクテーブル★
[★]
- 英
- β-lactam antibiotics, beta-lactam antibiotic
- 同
- β-ラクタム化合物 β-lactam compound
- 関
- 抗菌薬
種類
特徴
- 抗菌力が強い
- 抗菌スペクトルが広い
- 副作用が少ない
構造
副作用
- アレルギー(過敏症)
- 菌交代症(偽膜性大腸菌)
- 腎障害
- 肝障害
- アンタビューズ様作用、ビタミンK代謝障害
[★]
- 関
- combination、compositus、mixture