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1. 表皮水疱症のマネージメントの概要overview of the management of epidermolysis bullosa [show details]
…ignoring of premature termination codon mutations in patients with recessive diseases. At least 25 percent of RDEB patients have one or two premature termination codon mutations in the COL7A1 gene. Almost…
2. 遺伝学：用語集genetics glossary of terms [show details]
…synonymous variants. Nonsense variants are coding variants that result in the introduction of a stop codon A frameshift mutation results from an insertion or deletion of a number of bases not divisible by …
3. 分子遺伝学の原理principles of molecular genetics [show details]
… exceptions of three stop or termination codons. Most amino acids can be specified by more than one codon, termed functional redundancy or degeneracy One codon, AUG, serves the dual functions of signaling …
4. 遺伝性疾患の基本原則basic principles of genetic disease [show details]
…acids in a protein through the process of translation, whereby specific groups of three nucleotides (codons) correspond to one of 20 amino acids. Human genetic information is primarily contained within…
5. 消化管間質腫瘍（GIST）の疫学、分類、臨床症状、予後の特徴、診断方法epidemiology classification clinical presentation prognostic features and diagnostic work up of gastrointestinal stromal tumors gist [show details]
…associated with an aggressive phenotype, including those affecting exon 9 and deletions involving codons 557 to 558 on KIT exon 11 . Over time, various prognostic models based upon site, size, mitotic…

Japanese Journal

Expression and Purification of the Recombinant Mature Bone Morphogenetic Protein-2 of Pinctada fucata in Escherichia coli and Comparison of the Codon Usage

宮下知幸,加藤弘隆,高木良介
Memoirs of the School of Biology-Oriented Science and Technology of Kinki University = 近畿大学生物理工学部紀要 (18), 1-7, 2006-09-01
… 融合タンパク質が発現しないのは成熟タンパク質のN末端部分にアルギニンが多数存在しており、その対応コドンであるAGA,AGGおよびCGGが大腸菌では殆ど使用されないことに起因すると考えられる。 …
NAID 110006183410