WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
affecting an entire system; "a systemic poison"
any of several fat-soluble organic compounds having as a basis 17 carbon atoms in four rings; many have important physiological effects

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
(身体・言語のように)体系の,組織の / 全身の,全身的
ステロイド(脂肪溶解性の有機化合物の総称)

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A 4-year observation in lupus nephritis patients treated with an intensified B-lymphocyte depletion without immunosuppressive maintenance treatment-Clinical response compared to literature and immunological re-assessment.

Roccatello D1, Sciascia S2, Baldovino S2, Rossi D2, Alpa M2, Naretto C2, Di Simone D2, Simoncini M2, Menegatti E2.
Autoimmunity reviews.Autoimmun Rev.2015 Dec;14(12):1123-30. doi: 10.1016/j.autrev.2015.07.017. Epub 2015 Aug 2.
BACKGROUND: B cells (BC) play a critical role in systemic lupus erythematosus (SLE). BC depletion therapy still remains an attractive option, despite the disappointing results of randomized controlled trials (RTCs).METHODS: Twelve patients with SLE [3 males, mean age 43.8yrs (25-55)] with severe mul
PMID 26244817

Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells.

Pike JW1, Meyer MB2, St John HC2, Benkusky NA2.
Bone.Bone.2015 Dec;81:757-64. doi: 10.1016/j.bone.2015.03.012. Epub 2015 Mar 27.
Genomic annotation of unique and combinatorial epigenetic modifications along with transcription factor occupancy is having a profound impact on our understanding of the genome. These studies have led to a better appreciation of the dynamic nature of the epigenetic and transcription factor binding c
PMID 25819039

Jang SH1, Yun SJ1, Lee SC1, Lee JB1.
Clinical and experimental dermatology.Clin Exp Dermatol.2015 Dec;40(8):868-71. doi: 10.1111/ced.12530. Epub 2014 Dec 26.
Lichen planus pemphigoides (LPP) is a rare autoimmune dermatosis with the features of both lichen planus (LP) and bullous pemphigoid (BP). Although in rare cases, LPP has been associated with several medications and conditions, it is generally considered an idiopathic disorder, and its pathogenesis
PMID 25546603

沖本二郎,林敏清,栗原武幸,宮下修行
気管支学 : 日本気管支研究会雑誌 36(3), 293-297, 2014-05-25
背景.呼気一酸化窒素(fractional exhaled nitric oxide,FeNO)は,気道における好酸球性炎症の指標として,気管支喘息の診断や治療に臨床応用されている.私たちは,FeNO測定により好酸球性肺炎の病勢を追跡した.症例.68歳の男性で,咳嗽,呼吸困難,微熱を訴え,胸部X線写真では,両側上中肺野の末梢側優位に,スリガラス様陰影を認めた.白血球は13,600/μl,好酸球は3 …
NAID 110009823540

Safety of Tacrolimus Treatment during Pregnancy and Lactation in Systemic Lupus Erythematosus: A Report of Two Patients

Izumi Yasumori,Miyashita Taiichiro,Migita Kiyoshi
The Tohoku Journal of Experimental Medicine 234(1), 51-56, 2014
… Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects women of childbearing years. … Recently, tacrolimus has been used for steroid-resistant SLE. …
NAID 130004685013

羽田孝司,夏秋優,谷口怜子,山西清文,齋藤正紀
皮膚の科学 13(2), 79-83, 2014
57歳，男性。慢性C型肝炎に対してペグインターフェロン α-2b，リバビリン，テラプレビルの3剤併用療法を開始し，約7週間後から全身にそう痒を伴う浸潤性紅斑が出現した。皮疹部の生検所見は多形滲出性紅斑型の組織像であった。被疑薬を中止した上で，ステロイド薬全身投与を行い，皮疹は軽快した。リバビリン，テラプレビルおよびオキシプリノールによるパッチテスト，リンパ球刺激試験はいずれも陰性であった。テラプレ …
NAID 130004679568