催眠薬
English Journal
- Analytical methodologies for the determination of benzodiazepines in biological samples.
- Persona K1, Madej K2, Knihnicki P1, Piekoszewski W3.
- Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Feb 17. pii: S0731-7085(15)00113-2. doi: 10.1016/j.jpba.2015.02.017. [Epub ahead of print]
- Benzodiazepine drugs belong to important and most widely used medicaments. They demonstrate such therapeutic properties as anxiolytic, sedative, somnifacient, anticonvulsant, diastolic and muscle relaxant effects. However, despite the fact that benzodiazepines possess high therapeutic index and are
- PMID 25779536
- Antisomnogenic cytokines, quality of life, and chronic rhinosinusitis: a pilot study.
- Alt JA1, Sautter NB, Mace JC, Detwiller KY, Smith TL.
- The Laryngoscope.Laryngoscope.2014 Apr;124(4):E107-14. doi: 10.1002/lary.24412. Epub 2013 Oct 22.
- OBJECTIVES/HYPOTHESIS: Sleep disturbance, reduced quality of life (QOL), and other components of "sickness behavior" in patients with chronic rhinosinusitis (CRS) are poorly understood. These complex changes in central behavior are due to the effects of immune mediators acting in the brain. We hypot
- PMID 24115141
Japanese Journal
- 睡眠薬について : 内科・心療内科領域における不眠および睡眠薬の実態(心身症に対する新しい薬物療法)(第35回日本心身医学会総会)
Related Links
- somnifacient som·ni·fa·cient (sŏm'nə-fā'shənt) adj. Tending to produce sleep; soporific.
- somnifacient /som·ni·fa·cient/ (som″nĭ-fa´shint) hypnotic (1, 2). som·ni·fa·cient (sŏm′nə-fā′shənt) adj. Tending to produce sleep; soporific. som′ni·fa′cient n. somnifacient [som″nĭ-fa´shent] 1. hypnotic (def. 1). 2. hypnotic (def. 2). ...
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★リンクテーブル★
[★]
- 英
- hypnotic, hypnotics
- 同
- 催眠薬 somnifacient
- 関
- 睡眠、薬理学、睡眠障害、中枢神経抑制薬
- 正常な睡眠と同じような中枢作用を示す薬
- http://www.gifuyaku.or.jp/fumin.pdf
- http://www.tokyo-med.ac.jp/pharmacol/pdf/news_suimin0910.pdf
- http://mentalsupli.com/medication/sleeping-drug/summary-sleeping-drug/sleep-choice/
- http://seseragi-mentalclinic.com/sleepingdrug/
睡眠薬
- (1) 薬物依存性が高い、(2) REM睡眠が短縮しやすい、(4) 過量により急性中毒→抗痙攣薬、抗てんかん薬としての適応
分類
-
-
- ω2受容体への作用が弱く、転倒リスクが少ない。高齢者の筋弛緩作用に関与。反跳性不眠が比較的少ない。
- 持ち越し効果に注意。逆に、抗不安作用を期待して使用することも
-
- flutoparazepam
- fluurazepam
- rilnazafone
投与制限
睡眠障害
- 睡眠障害の型に合わせた処方
- 何で眠れないのか聴取。身体的要因、環境整備、
- 睡眠障害の型を聴取する。