WordNet

to a lower intensity; "he slowly phased down the light until the stage was completely black"
soft fine feathers (同)down feather
(American football) a complete play to advance the football; "you have four downs to gain ten yards"
fine soft dense hair (as the fine short hair of cattle or deer or the wool of sheep or the undercoat of certain dogs) (同)pile
(usually plural) a rolling treeless highland with little soil
understood perfectly; "had his algebra problems down" (同)down pat, mastered
extending or moving from a higher to a lower place; "the down staircase"; "the downward course of the stream" (同)downward
spatially or metaphorically from a higher to a lower level or position; "dont fall down"; "rode the lift up and skied down"; "prices plunged downward" (同)downwards, downward, downwardly
cause to come or go down; "The policeman downed the heavily armed suspect"; "The mugger knocked down the old lady after she refused to hand over her wallet" (同)knock down, cut_down, push down, pull down
shoot at and force to come down; "the enemy landed several of our aircraft" (同)shoot down, land
away from a more central or a more northerly place; "was sent down to work at the regional office"; "worked down on the farm"; "came down for the wedding"; "flew down to Florida"
becoming progressively lower; "the down trend in the real estate market"
being or moving lower in position or less in some value; "lay face down"; "the moon is down"; "our team is down by a run"; "down by a pawn"; "the stock market is down today"
being put out by a strikeout; "two down in the bottom of the ninth"
bring down or defeat (an opponent)
from an earlier time; "the story was passed down from father to son"
in an inactive or inoperative state; "the factory went down during the strike"; "the computer went down again"
not functioning (temporarily or permanently); "we cant work because the computer is down"
paid in cash at time of purchase; "put ten dollars down on the necklace"
shut; "the shades were down"
form a community; "The Swedes settled in Minnesota"
a long wooden bench with a back (同)settee
get ones revenge for a wrong or an injury; "I finally settled with my old enemy" (同)get back
take up residence and become established; "The immigrants settled in the Midwest" (同)locate
become settled or established and stable in ones residence or life style; "He finally settled down" (同)root, take root, steady down, settle_down
settle into a position, usually on a surface or ground; "dust settled on the roofs" (同)settle_down
settle conclusively; come to terms; "We finally settled the argument" (同)square off, square_up, determine
accept despite lack of complete satisfaction; "We settled for a lower price"
arrange or fix in the desired order; "She settled the teacart"
become clear by the sinking of particles; "the liquid gradually settled"
become resolved, fixed, established, or quiet; "The roar settled to a thunder"; "The wind settled in the West"; "it is settling to rain"; "A cough settled in her chest"; "Her mood settled into lethargy"
cause to become clear by forming a sediment (of liquids)
come to rest
dispose of; make a financial settlement
end a legal dispute by arriving at a settlement; "The two parties finally settled"
establish or develop as a residence; "He settled the farm 200 years ago"; "This land was settled by Germans"
travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
carry on or function; "We could do with a little more help around here" (同)manage
get (something) done; "I did my job" (同)perform
not changeable; "a period of settled weather"
established in a desired position or place; not moving about; "nomads...absorbed among the settled people"; "settled areas"; "I dont feel entirely settled here"; "the advent of settled civilization"
established or decided beyond dispute or doubt; "with details of the wedding settled she could now sleep at night"
English physician who first described Downs syndrome (1828-1896) (同)John L. H. Down

PrepTutorEJDIC

(高い所から)『下へ』,降りて,地面へ / (地理・地図上)南へ,下町へ;(風・流れなどが)『下(しも)手へ』;《英》(都会・大学から)地方へ,離れて / (価格・品質・温度などが)『下がって』,(数量・スピードなどが)少なく,減じて,(濃度が)薄く / (健康・風の勢いなどが)『衰えて』,気分が沈んで / (時代などが)下がって,…に至るまで / (身分・地位が)下がって / (紙面に)書き留めて,記録して / (頭金を)現金で,即金で / 最後まで,徹底的に / しっかりと,動けないように / (高い所から)…『を下がって』;…『に沿って』;…の向こうに / …の下流に / …以来 / 《名詞の前にのみ用いて》『下りの』,下への / 《名詞の前にのみ用いて》(列車・バスなどが)下りの / 《補語にのみ用いて》下に,下がって / 《補語にのみ用いて》弱まった,おさまった;落胆した,元気のない / 《補語にのみ用いて》(勝負で)負けて,すって / 《補語にのみ用いて》《おもに米話》(野球で)アウト / …‘を'打倒する,負かす,撃ち落とす / …‘を'飲み干す,飲み込む / 下り,下降 / 《複数形で》不運,逆境
(鳥の)綿毛,うぶ毛,下羽 / (植物・果実の表面の)柔らかい毛
なだらかな草原地,丘陵地帯(特にイングランド南部の小高い白亜質の草原地the Downsを言う)
…‘を'『決定する』,〈日取りなど〉‘を'決める,〈問題など〉‘を'解決する / …‘を'整理する,整とんする / 〈勘定など〉‘を'清算する,支払う / (…に)〈財産など〉‘を'譲る《+『名』+『on』+『名』》 / 〈ある地域〉‘に'植民する / …‘を'『安定させる』,調節する / 〈神経・胃など〉‘を'『静める』,落ち着かせる / 〈液体〉‘を'澄ませる / 〈かす・おりなど〉‘を'沈ませる,沈殿させる / (…に)決定する,決める《+『on』(『upon』)+『名』(do『ing』)》 / (…に)定住する《+『in』+『名』》 / 〈鳥などが〉(…に)とまる,降りる《+『on』+『名』》 / 徐々に沈む
(ひじ掛けつきで背が高い2,2人掛けの)木製のベンチ
《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
ド(全音階の第1音)
変りのない,固定した / 人の住んでいる / 清算済みの

UpToDate Contents

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1. ダウン症：臨床的特徴および診断 down syndrome clinical features and diagnosis
2. ダウン症：マネージメント down syndrome management
3. ダウン症候群：出生前スクリーニングの概要 down syndrome overview of prenatal screening
4. Transient myeloproliferative disorder of Down syndrome
5. First-trimester combined test and integrated tests for screening for Down syndrome and trisomy 18

English Journal

Administering the Optimum Dose of l-Arginine in Regional Tumor Therapy.

Moawad EY1.
Indian journal of clinical biochemistry : IJCB.Indian J Clin Biochem.2014 Oct;29(4):442-51. doi: 10.1007/s12291-013-0379-z. Epub 2013 Sep 15.
The purpose of this study is optimizing the l-arginine (l-Arg) doses on the basis of chemical structure in regional accessible tumor therapy to settle down a new protocol for the treatment of cancer. (3)H-thymidine-based cell proliferation assay was performed in vitro on tumor cell lines of fibrosar
PMID 25298625

Hydrogel thin film with swelling-induced wrinkling patterns for high-throughput generation of multicellular spheroids.

Zhao Z1, Gu J, Zhao Y, Guan Y, Zhu XX, Zhang Y.
Biomacromolecules.Biomacromolecules.2014 Sep 8;15(9):3306-12. doi: 10.1021/bm500722g. Epub 2014 Aug 4.
Three-dimensional (3D) multicellular spheroids (MCSs) mimic the structure and function of real tissue much better than the conventional 2D cell monolayers, however, their application was severely hindered by difficulties in their generation. An ideal method for MCS fabrication should produce spheroi
PMID 25072634

Isolation and processing of silk proteins for biomedical applications.

Kundu B1, Kurland NE2, Yadavalli VK3, Kundu SC4.
International journal of biological macromolecules.Int J Biol Macromol.2014 Sep;70:70-7. doi: 10.1016/j.ijbiomac.2014.06.022. Epub 2014 Jun 24.
Silk proteins of silkworms are chiefly composed of core fibroin protein and glycoprotein sericin that glues fibroin. Unique mechanical properties, cyto-compatibility and controllable biodegradability facilitate the use of fibroin in biomedical applications. Sericin serves as additive in cosmetic and
PMID 24971560