- 関
- premature ovarian failure
WordNet
- impervious to being affected; "resistant to the effects of heat"; "resistant to persuasion"
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
- the organ that bears the ovules of a flower
- (vertebrates) one of usually two organs that produce ova and secrete estrogen and progesterone
PrepTutorEJDIC
- 抵抗力のある;(…に)抵抗する《+『to』+『名』》
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
- 卵巣 / (花の)子房
- ovumの複数形
UpToDate Contents
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English Journal
- Alterations in thyroid function among the different polycystic ovary syndrome phenotypes.
- Morgante G, Musacchio MC, Orvieto R, Massaro MG, De Leo V.SourceDepartment of Pediatrics, Obstetrics and Reproductive Medicine, Institute of Obstetrics and Gynecology, University of Siena , Siena , Italy and.
- Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.Gynecol Endocrinol.2013 Nov;29(11):967-969. Epub 2013 Aug 19.
- Abstract The study evaluates the prevalence of subclinical thyroid dysfunction in infertile PCOS patients, according to the different PCOS phenotypes and to examine whether insulin sensitizers in insulin resistant (IR) PCOS patients may improve thyroid function. The study population consisted of all
- PMID 23957782
- A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency.
- Wu X, Wang B, Dong Z, Zhou S, Liu Z, Shi G, Cao Y, Xu Y.SourceMOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 12 Xuefu Road, Pukou District, Nanjing, China.
- Cell death & disease.Cell Death Dis.2013 Oct 3;4:e825. doi: 10.1038/cddis.2013.368.
- Primary ovarian insufficiency (POI), or premature ovarian failure, is defined as the cessation of ovarian function before the age of 40. An insufficient ovarian follicle pool derived from primordial germ cells (PGCs) is an important cause of POI. Although the Nanos gene family is known to be require
- PMID 24091668
- Investigating the Role of Tbx4 in the Female Germline in Mice.
- Douglas NC, Arora R, Chen CY, Sauer MV, Papaioannou VE.AbstractNormal development of germ cells is essential for fertility and mammalian reproduction. Although abnormal development of oocytes or follicles may lead to primary ovarian insufficiency (POI), a disorder that causes infertility in 1% of women less than 40 yr of age, the genes and signaling pathways activated in POI are not as yet fully elucidated. Tbx4, a member of the T-box family of transcription factors, is expressed in embryonic germ cells and postnatal oocytes at all stages of folliculogenesis. To investigate the requirement for Tbx4 in the germline, we analyzed germ cell development in the absence of Tbx4. We show that primordial germ cells (PGCs) are reduced in Tbx4 homozygous null (Tbx4-/-) embryos at Embryonic Day (E) 10.0. Tbx4-/- embryos die by E10.5; to study later time points in vitro a tamoxifen inducible estrogen receptor Cre recombinase was used to delete Tbx4 conditional mutant alleles. In addition, Gdf9cre and Zp3cre, two oocyte-specific Cre recombinases, were used to delete Tbx4 from postnatal primordial and primary follicles, respectively. We show that in vitro differentiation of the gonad into morphologically distinct testes and ovaries occurs normally when Tbx4 is deleted starting at E11.5. In Gdf9cre; Tbx4fl/- and Zp3cre; Tbx4fl/- adult females, primordial, primary, secondary, and antral follicles form, ovulation occurs, corpus luteum formation is normal, and the mice are fertile without any evidence of diminished ovarian reserve. Although postnatal deletion of Tbx4 in oocytes does not obviously impair fertility, it is possible that the reduction in PGCs observed in Tbx4 homozygous null mutant embryos could affect long-term fertility in adults.
- Biology of reproduction.Biol Reprod.2013 Oct 2. [Epub ahead of print]
- Normal development of germ cells is essential for fertility and mammalian reproduction. Although abnormal development of oocytes or follicles may lead to primary ovarian insufficiency (POI), a disorder that causes infertility in 1% of women less than 40 yr of age, the genes and signaling pathways ac
- PMID 24089201
Japanese Journal
- クロミフェン無効な多嚢胞性卵巣症候群に対し,柴苓湯の併用療法が奏効した6症例の検討
- Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls
- Peroxisome Proliferator-activated Receptor-γ agonists Prevent Tumor Necrosis Factor-α-mediated Inhibition of FSH-induced Follicle Development and Estradiol Production in A PreantralFollicle Culture System
Related Links
- resistant ovary syndrome resistant ovary syndrome Premature ovarian failure, see there. re·sis·tant o·va·ry syn·drome [MIM*176440] amenorrhea associated with hypergonadotrophism and usually normal ovarian follicles; may be ...
- resistant ovary syndrome definition from the mondofacto online medical dictionary ... help contact sitemap resistant ovary syndrome definition home dictionary word tools courses study skills forum about us Search dictionary help
Related Pictures
★リンクテーブル★
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- 英
- resistant ovary syndrome
- 関
- 早発閉経
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ゴナドトロピン抵抗性卵巣症候群
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- 関
- recalcitrance、refractory、resist、resistance、resistive、stand、tolerance、tolerant、withstand
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- 関
- egg、egg cell、oval、ovule、ovum、unfertilized egg、vitelline
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