WordNet

relating to or occurring on the undersurface of the foot; "plantar warts can be very painful"
relating to the palm of the hand or the sole of the foot; "the volar surface"; "the palmar muscle" (同)volar
the base of the natural system of logarithms; approximately equal to 2.718282...

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足の裏の,足底の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/06 07:01:58」(JST)

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Pustulosis palmaris et plantaris (also known as "Pustulosis of palms and soles,"^[1] "Palmoplantar pustulosis," "Persistent palmoplantar pustulosis," "Pustular psoriasis of the Barber type," and "Pustular psoriasis of the extremities") is a chronic recurrent pustular dermatosis localized on the palms and soles only, characterized histologically by intraepidermal vesicles filled with neutrophils.^[2]^:411,628^[3]^:204

References

^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

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UpToDate Contents

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1. 好中球性皮膚症 neutrophilic dermatoses
2. 膿疱性皮膚病変を有する患者へのアプローチ approach to the patient with pustular skin lesions
3. 急性掌蹠湿疹（異汗性湿疹） acute palmoplantar eczema dyshidrotic eczema
4. 汗孔角化症 porokeratosis
5. 乾癬の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of psoriasis

English Journal

Phosphospecific flow cytometry for pharmacodynamic drug monitoring: Analysis of the JAK-STAT signaling pathway.

Vafadari R, Weimar W, Baan CC.AbstractCytokines of the IL-2 receptor family act via activation of the JAK-STAT (janus tyrosine kinase-signal transducer and activator of transcription) signaling pathway. These cytokines are pivotal for the development and function of lymphocyte subsets involved in the immune response after organ transplantation including T, B and natural killer cells. The new small drug molecule and JAK1/3 inhibitor, tofacitinib, is currently being tested in phase II and III clinical trials for rheumatoid arthritis, psoriasis and in organ transplantation. This agent specifically targets the JAK-STAT signaling pathway. Here we discuss phosphospecific flow cytometry as a novel tool to monitor the JAK-STAT signaling pathway in kidney transplant patients and speculate that through the use of this pharmacodynamic tool the efficacy of immunosuppressive drugs can be assessed enabling optimization of the immunosuppressive therapy for individual transplant patients.
Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2012 Sep 8;413(17-18):1398-405. Epub 2012 Jan 10.
Cytokines of the IL-2 receptor family act via activation of the JAK-STAT (janus tyrosine kinase-signal transducer and activator of transcription) signaling pathway. These cytokines are pivotal for the development and function of lymphocyte subsets involved in the immune response after organ transpla
PMID 22261016

G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions.

Jacobson KA, Balasubramanian R, Deflorian F, Gao ZG.SourceLaboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. kajacobs@helix.nih.gov
Purinergic signalling.Purinergic Signal.2012 Sep;8(3):419-36. Epub 2012 Feb 29.
The medicinal chemistry and pharmacology of the four subtypes of adenosine receptors (ARs) and the eight subtypes of P2Y receptors (P2YRs, activated by a range of purine and pyrimidine mono- and dinucleotides) has recently advanced significantly leading to selective ligands. X-ray crystallographic s
PMID 22371149