オレゴボマブ
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/01/13 16:19:38」(JST)
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Oregovomab ?
Monoclonal antibody |
Type |
Whole antibody |
Source |
Mouse |
Target |
CA125 |
Clinical data |
Trade names |
OvaRex |
Legal status |
?
|
Identifiers |
CAS number |
213327-37-8 N |
ATC code |
None |
KEGG |
D05269 Y |
Chemical data |
Formula |
? |
Molecular mass |
ca. 150 kDa |
N (what is this?) (verify) |
Oregovomab (marketed under the trade name OvaRex) is a mouse monoclonal antibody it binds to the antigen CA125, a carbohydrate antigen. It is designed for the treatment of ovarian cancer.[1]
This drug was developed by AltaRex Corp.
Adverse drug effects
|
This section is empty. You can help by adding to it. (October 2014) |
References
- ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Oregovomab, American Medical Association.
English Journal
- Monoclonal antibodies in gynecological cancer: a critical point of view.
- Bellati F, Napoletano C, Gasparri ML, Visconti V, Zizzari IG, Ruscito I, Caccetta J, Rughetti A, Benedetti-Panici P, Nuti M.SourceDepartment of Gynecology and Obstetrics, Sapienza University of Rome, Italy.
- Clinical & developmental immunology.Clin Dev Immunol.2011;2011:890758. Epub 2011 Dec 26.
- During the last decades, several improvements in treating gynecological malignancies have been achieved. In particular, target therapies, mostly monoclonal antibodies, have emerged as an attractive option for the treatment of these malignancies. In fact, various molecular-targeted agents have been d
- PMID 22235224
- Preclinical studies and clinical utilization of monoclonal antibodies in epithelial ovarian cancer.
- Frederick PJ, Straughn JM Jr, Alvarez RD, Buchsbaum DJ.SourceDivision of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA. pfrederick5@hotmail.com
- Gynecologic oncology.Gynecol Oncol.2009 Jun;113(3):384-90. Epub 2009 Feb 20.
- OBJECTIVE: To present an overview of selected monoclonal antibodies (mAbs) that have been studied in epithelial ovarian cancer with a focus on combination treatment with conventional chemotherapy.METHODS: The authors perform a narrative review of the literature. Preclinical studies that provided rat
- PMID 19232697
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