- 関
- optic nerve disorder、optic nerve transection、optic nerve trauma、traumatic optic neuropathy
WordNet
- any physical damage to the body caused by violence or accident or fracture etc. (同)hurt, harm, trauma
- an act that causes someone or something to receive physical damage
- wrongdoing that violates anothers rights and is unjustly inflicted
- an accident that results in physical damage or hurt (同)accidental injury
- any bundle of nerve fibers running to various organs and tissues of the body (同)nervus
- optical properties; "the optics of a telescope"
- the branch of physics that studies the physical properties of light
PrepTutorEJDIC
- 『負傷』,『損害』,損傷 / (名誉などを)傷つけること,侮辱《+『to』+『名』》
- 〈C〉『神経』 / 〈C〉《複数形で》『神経過敏』,いらだち / 〈U〉『勇気』,度胸(courage) / 〈U〉《時にa ~》厚かましさ,ずぶとさ;無礼 / 〈C〉葉脈;(昆虫の)翅脈(しみゃく) / 〈人,特に自分〉‘に'力を与える,‘を'元気づける
- 光学
- (・・・を)選ぶ《+『for』+『名』》;(・・・するほうを)選ぶ《+『to』 do》
- 目の;視覚の
UpToDate Contents
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English Journal
- Do growth-stimulated retinal ganglion cell axons find their central targets after optic nerve injury? New insights by three-dimensional imaging of the visual pathway.
- Diekmann H, Leibinger M, Fischer D.SourceDepartment of Neurology, Heinrich-Heine-University of Düsseldorf, Merowingerplatz 1a, 40225 Düsseldorf, Germany.
- Experimental neurology.Exp Neurol.2013 Oct;248:254-7. doi: 10.1016/j.expneurol.2013.06.021. Epub 2013 Jun 28.
- Retinal ganglion cells (RGCs) do not normally regenerate injured axons. However, several strategies to transform RGCs into a potent regenerative state have been developed in recent years. Intravitreal CNTF application combined with conditional PTEN and SOCS3 deletion or zymosan-induced inflammatory
- PMID 23816572
- Paxillin phosphorylation counteracts proteoglycan-mediated inhibition of axon regeneration.
- Kuboyama T, Luo X, Park K, Blackmore MG, Tojima T, Tohda C, Bixby JL, Lemmon VP, Kamiguchi H.SourceLaboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, Wako, Saitama 351-0198, Japan; Division of Neuromedical Science, Institute of Natural Medicine, University of Toyama, Toyama, Toyama 930-0194, Japan.
- Experimental neurology.Exp Neurol.2013 Oct;248:157-69. doi: 10.1016/j.expneurol.2013.06.011. Epub 2013 Jun 21.
- In the adult central nervous system, the tips of axons severed by injury are commonly transformed into dystrophic endballs and cease migration upon encountering a rising concentration gradient of inhibitory proteoglycans. However, intracellular signaling networks mediating endball migration failure
- PMID 23797153
- N-methyl-D-aspartate receptors strongly regulate postsynaptic activity levels during optic nerve regeneration.
- Kolls BJ, Meyer RL.SourceDepartment of Developmental and Cell Biology, University of California Irvine, Irvine, California; Brain Injury Translational Research Center, Division of Neurology, Duke University Medical Center, Durham, North Carolina.
- Journal of neuroscience research.J Neurosci Res.2013 Oct;91(10):1263-79. doi: 10.1002/jnr.23246. Epub 2013 Jul 19.
- During development, neuronal activity is used as a cue to guide synaptic rearrangements to refine connections. Many studies, especially in the visual system, have shown that the N-methyl-D-aspartate receptor (NMDAr) plays a key role in mediating activity-dependent refinement through long-term potent
- PMID 23873725
Japanese Journal
- Requirement of Retinoic Acid Receptor β for Genipin Derivative-Induced Optic Nerve Regeneration in Adult Rat Retina
- Koriyama Yoshiki,Takagi Yusuke,Chiba Kenzo,Yamazaki Matsumi,Sugitani Kayo,Arai Kunizo,Suzuki Hirokazu,Kato Satoru
- PLoS ONE 8(8), e71252, 2013-08-06
- … Like other CNS neurons, mature retinal ganglion cells (RGCs) are unable to regenerate their axons after nerve injury due to a diminished intrinsic regenerative capacity. … However, the role of RARβ expression during adult rat optic nerve regeneration is not clear. … In the present study, we extended this hypothesis to examine optic nerve regeneration by IPRG001 in adult rat RGCs in vivo. …
- NAID 120005327241
- Delayed Traumatic Optic Neuropathy : A Case Report
- 伊藤 誠康,大村 武久,三宅 裕治,辻 雅夫,浮田 透,英 賢一郎,山田 佳孝,Tucker Adam,上杉 哲平,中内 一楊
- Japanese Journal of Neurosurgery 22(2), 134-140, 2013
- … The patient was diagnosed with traumatic optic neuropathy and the symptoms improved after a course of steroid pulse therapy. … Cranial CT and MRI were unremarkable except for a small fracture on the left postero-lateral orbital wall with no evidence of optic canal fracture. … Normal findings on fundoscopy and fluorescent angiography suggested posterior optic nerve injury. …
- NAID 130003379595
- 中枢神経修復・再生におけるタンパク質のS-ニトロシル化の役割
- 郡山 恵樹
- YAKUGAKU ZASSHI 133(8), 843-848, 2013
- … The optic nerve injury is a well-accepted model to study the mechanisms of neural degeneration and/or axonal regeneration after trauma in the CNS. … Especially, whether S-nitrosylation of proteins promotes RGCs survival and its axonal regeneration after injury is unclear. … Thus, we focused on the S-nitrosylation-dependent mechanism of RGCs survival and axonal regeneration by NO after nerve injury. …
- NAID 130003361977
Related Links
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Related Pictures
★リンクテーブル★
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- 英
- optic nerve injury、optic nerve disorder
- 関
- 視神経切断、視神経損傷、外傷性視神経症
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外傷性視神経症
- 関
- optic nerve injury、optic nerve transection、optic nerve trauma
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- 関
- optic nerve injury、optic nerve trauma、traumatic optic neuropathy
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- 英
- optic nerve injury
- 関
- 視神経障害
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視神経障害
- 関
- optic nerve injury
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- 関
- damage、injure、insult、lesion、spoilage、trauma、traumatic、traumatic injury、wound
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- 関
- choice、choose、elect、elective、option、optional、prefer、select、selection、selective
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- 関
- nervi、nervous、nervus、neural、neuro、neuron
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- 関
- ocular、vision、visual
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- 関
- optical