olfactory marker protein

嗅覚標識タンパク質

関

OMP

WordNet

1. make or leave a mark on; "the scouts marked the trail"; "ash marked the believers foreheads"
2. formerly the basic unit of money in Germany (同)German mark, Deutsche Mark, Deutschmark
3. the impression created by doing something unusual or extraordinary that people notice and remember; "it was in London that he made his mark"; "he left an indelible mark on the American theater"
4. a number or letter indicating quality (especially of a students performance); "she made good marks in algebra"; "grade A milk"; "what was your score on your homework?" (同)grade, score
5. a visible indication made on a surface; "some previous reader had covered the pages with dozens of marks"; "paw prints were everywhere" (同)print
6. a symbol of disgrace or infamy; "And the Lord set a mark upon Cain"--Genesis (同)stigma, brand, stain
7. a written or printed symbol (as for punctuation); "his answer was just a punctuation mark"
8. designate as if by a mark; "This sign marks the border"
9. a writing implement for making a mark
10. some conspicuous object used to distinguish or mark something; "the buoys were markers for the channel"
11. a distinguishing symbol; "the owners mark was on all the sheep" (同)marking, mark
12. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
13. of or relating to olfaction (同)olfactive

PrepTutorEJDIC

1. 〈C〉(…の表面についた)『跡』,汚れ,はん点《+『on』+『名』》 / 〈C〉『印』,記号,符号,標章 / 〈C〉《おもに英》(学業などの)『点数』,成績,評価,(…の)得点《+『in』(『for』)+『名』》 / 〈C〉(ある性質の)『徴候』,『特徴』,現れ,様相《+『of』+『名』》 / 〈C〉(思想・生活などに及ぼす)『影響』,感化《+『on』+『名』》 / 〈C〉(境界などの)位置を示すもの,指標,目印 / 〈C〉『的』,標的 / 〈C〉《the mark》水準,標準 / 〈U〉《文》著名,重要性;名声 / 〈C〉(軽べつ・もの笑いなどの)対象,的 / 〈U〉《通例M-》武器記号,…型 / 〈C〉スタートライン / (…で)…‘に'『印をつける』,跡をつける《+『名』++『with』+『名』》 / 〈物が〉…‘を'印となっている,‘を'示している / …‘を'印(記号など)で示す / 〈物・事柄などが〉…‘を'『特徴づける』,目立たせる / 〈答案など〉‘に'点(印)をつける / (…の候補に)…‘を'選び出す《+『名』+『out for』+『名』》 / …‘に'注意を払う,柱目する
2. マルク(ドイツノ貨幣単位;《略》『MK.』)
3. 印をつける人(道具) / (ゲームなどの)採点者 / 目印,目標
4. 蛋白(たんばく)質
5. 嗅覚(きゅうかく)の / 嗅覚器官,鼻

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/06 01:37:21」(JST)

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olfactory marker protein
Identifiers
Symbol	OMP
Entrez	4975
HUGO	8136
OMIM	164340
RefSeq	NM_006189
UniProt	P47874
Other data
Locus	Chr. 11 q14-q21

Olfactory marker protein
solution structure of olfactory marker protein from rat
Identifiers
Symbol	Olfactory_mark
Pfam	PF06554
InterPro	IPR009103
SCOP	1jyt
SUPERFAMILY	1jyt
Available protein structures: Pfam structures PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

In molecular biology, olfactory marker protein is a protein involved in signal transduction. It is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory signal transduction cascade. The crystal structure of OMP reveals a beta sandwich consisting of eight strands in two sheets with a jelly-roll topology. Three highly conserved regions have been identified as possible protein-protein interaction sites in OMP, indicating a possible role for OMP in modulating such interactions, thereby acting as a molecular switch.

External links

• Olfactory marker protein at the US National Library of Medicine Medical Subject Headings (MeSH)

References

This article incorporates text from the public domain Pfam and InterPro IPR009103

UpToDate Contents

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• 1. 味覚および嗅覚障害の解剖学および病因 anatomy and etiology of taste and smell disorders
• 2. 幼児の食物蛋白誘発性直腸炎/大腸炎および腸疾患 food protein induced proctitis colitis and enteropathy of infancy
• 3. 活性化プロテインＣ抵抗性および第V因子ライデン activated protein c resistance and factor v leiden
• 4. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
• 5. 蛋白質摂取制限と慢性腎臓病の進行 protein restriction and progression of chronic kidney disease

English Journal

• Low dose tubulin-binding drugs rescue peroxisome trafficking deficit in patient-derived stem cells in Hereditary Spastic Paraplegia.

• Fan Y1, Wali G1, Sutharsan R1, Bellette B1, Crane DI1, Sue CM2, Mackay-Sim A3.
• Biology open.Biol Open.2014 May 23. pii: BIO20147641. doi: 10.1242/bio.20147641. [Epub ahead of print]
• Hereditary Spastic Paraplegia (HSP) is a genetically heterogeneous group of disorders, diagnosed by progressive gait disturbances with muscle weakness and spasticity, for which there are no treatments targeted at the underlying pathophysiology. Mutations in spastin are a common cause of HSP. Spastin
• PMID 24857849

• Stereological quantification of olfactory receptor neurons in mice.

• Kawagishi K1, Ando M2, Yokouchi K2, Sumitomo N2, Karasawa M2, Fukushima N2, Moriizumi T2.
• Neuroscience.Neuroscience.2014 May 4;272C:29-33. doi: 10.1016/j.neuroscience.2014.04.050. [Epub ahead of print]
• The total number of olfactory receptor neurons (ORNs) in the mouse main olfactory epithelium (MOE) was estimated using stereological sampling. Noses and skulls of male and female 8-week-old C57BL/6J mice were de-calcified, embedded in paraffin, cut into 10-μm-thick sections serially at 100-μm inte
• PMID 24797329

• Genome-wide association study for poor sperm motility in Holstein-Friesian bulls.

• Hering DM1, Olenski K1, Kaminski S2.
• Animal reproduction science.Anim Reprod Sci.2014 May;146(3-4):89-97. doi: 10.1016/j.anireprosci.2014.01.012. Epub 2014 Feb 7.
• The aim of the study was to screen the whole bull genome to identify markers and candidate genes underlying poor sperm motility. The analyzed data set originates from the Polish Holstein-Friesian bull population and consists of 41 Case and 279 Control bulls (selected from 1581 bulls). The most disti
• PMID 24612955

Japanese Journal

• 成体マウス脳における嗅覚系新生ニューロンの遊走に関する三次元構造解析

• 川崎医学会誌 41(1), 57-73, 2015
• NAID 110009924810

• バルプロ酸ナトリウムはメチマゾールによるマウス嗅上皮傷害モデルにおいて嗅神経再生を促進する

• 耳鼻咽喉科免疫アレルギー 32(3), 191-195, 2014
• NAID 130004697458

• Evaluation of the Safety and Brain-Related Tissues Distribution Characteristics of TAT-HaFGF <i>via</i> Intranasal Administration

• Biological and Pharmaceutical Bulletin 37(7), 1149-1157, 2014
• NAID 130004057422

Related Links

• Olfactory Marker Protein Is Critical for Functional Maturation of ...

Animals. Genetically targeted MOR23-IRES (internal ribosome entry site)-tauGFP mice were used to record MOR23 neurons that coexpress green fluorescent protein (GFP) (Vassalli et al., 2002). To obtain OMP −/− ...

• Olfactory marker protein (IPR009103) < InterPro < EMBL-EBI

Olfactory marker protein (OMP) is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory signal transduction cascade. The crystal structure of ...

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★リンクテーブル★

リンク元	「OMP」「嗅覚標識タンパク質」「嗅標識蛋白質」
関連記事	「mark」「marker」「marker protein」「olfactory」

「OMP」

　　[★]

• オロチジン5'-一リン酸 orotidine 5'-phosphate。orotidine monophosphate
• 嗅標識蛋白質 olfactory marker protein
• 外膜タンパク質 outer membrane proteins

「嗅覚標識タンパク質」

　　[★]

英

olfactory marker protein、OMP

関

外膜タンパク質

「嗅標識蛋白質」

　　[★]

英

olfactory marker protein, OMP

「mark」

　　[★]

• n.

• マーク

• v.

• 標識する、特徴づける

関

characterise、characterize、label、labeling、landmark、marker、marking、tag

　 　 　 　 　 　 　 　 　 　

「marker」

　　[★]

• n.

• マーカー、目印、標識、標識形質

関

label、labeling、landmark、mark、marking、tag

　 　 　 　

「marker protein」

　　[★]

• マーカータンパク質、マーカー蛋白質、マーカータンパク

「olfactory」

　　[★]

• adj.

• 嗅覚の

関

olfaction