WordNet

executed with proper legal authority; "a binding contract"
the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
strip sewn over or along an edge for reinforcement or decoration
the capacity to attract and hold something
territory over which rule or control is exercised; "his domain extended into Europe"; "he made it the law of the land" (同)demesne, land
(mathematics) the set of values of the independent variable for which a function is defined (同)domain of a function
a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA) (同)base

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1. 自然免疫系の概要 an overview of the innate immune system
2. マンノース結合レクチン欠損症 mannose binding lectin deficiency
3. マンノース結合レクチン mannose binding lectin
4. 周期性発熱症候群およびその他の自己炎症性疾患：概要 periodic fever syndromes and other autoinflammatory diseases an overview
5. 消化管疾患によるリウマチ症状の誘導のメカニズム mechanisms for the induction of rheumatic symptoms by gastrointestinal disease

β2-Adrenergic agonists bias TLR-2 and NOD2 activated dendritic cells towards inducing an IL-17 immune response.

Manni M, Granstein RD, Maestroni G.SourceCenter for Experimental Pathology, Cantonal Institute of Pathology, 6601 Locarno, Switzerland; Weill Cornell Medical College, Dermatology Department, New York, NY 10065, United States.
Cytokine.Cytokine.2011 Sep;55(3):380-6. Epub 2011 Jun 16.
This study tested the hypothesis that activation of β2-adrenoceptors on DCs influences NOD2 signaling along with its cross-talk with Toll-like receptor-2 resulting in altered Th cell priming ability. Th17 cells are a newly discovered lineage of CD4(+) T cells involved in defense against extracellul
PMID 21683614

NOD2, an intracellular innate immune sensor involved in host defense and Crohn's disease.

Strober W, Watanabe T.SourceLaboratory of Host Defenses, Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Mucosal immunology.Mucosal Immunol.2011 Sep;4(5):484-95. doi: 10.1038/mi.2011.29. Epub 2011 Jul 13.
Nucleotide-binding oligomerization domain 2 (NOD2) is an intracellular sensor for small peptides derived from the bacterial cell wall component, peptidoglycan. Recent studies have uncovered unexpected functions of NOD2 in innate immune responses such as induction of type I interferon and facilitatio
PMID 21750585