normal prion protein

• 正常プリオンタンパク質

関

PrP-sen、PrPC protein

WordNet

1. in accordance with scientific laws
2. being approximately average or within certain limits in e.g. intelligence and development; "a perfectly normal child"; "of normal intelligence"; "the most normal person Ive ever met"
3. conforming with or constituting a norm or standard or level or type or social norm; not abnormal; "serve wine at normal room temperature"; "normal diplomatic relations"; "normal working hours"; "normal word order"; "normal curiosity"; "the normal course of events"
4. forming a right angle
5. a standard or model or pattern regarded as typical; "the current middle-class norm of two children per family"
6. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
7. (microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system

PrepTutorEJDIC

1. 『正常な』,『通常の』,標準の / (人が肉体・知能・情緒の発達において)平均的な,年齢相応の / (線などが)垂直な;(…に)垂直な《+『to』+『名』》・普通の;典型的な;直角をなす (to)・（実験動物が）常態の, 未処置［未免疫］の;（濃度が）規定の・常態;垂線, 法線;平均量［値］正常,通常;標準
2. 《しばしば複数形で》標準,規準;一般水準;(行動の)規範,ノルマ・基準量(値)
3. 蛋白(たんばく)質

UpToDate Contents

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• 1. プリオンの生物学および遺伝学 biology and genetics of prions
• 2. クロイツフェルト・ヤコブ病 creutzfeldt jakob disease
• 3. プリオンによる中枢神経系疾患 diseases of the central nervous system caused by prions
• 4. 変異型クロイツフェルト・ヤコブ病 variant creutzfeldt jakob disease
• 5. アミロイド疾患の遺伝的要因 genetic factors in the amyloid diseases

English Journal

• Predictive testing for inherited prion disease: report of 22 years experience.

• Owen J1, Beck J2, Campbell T2, Adamson G2, Gorham M1, Thompson A3, Smithson S4, Rosser E5, Rudge P1, Collinge J3, Mead S3.
• European journal of human genetics : EJHG.Eur J Hum Genet.2014 Dec;22(12):1351-6. doi: 10.1038/ejhg.2014.42. Epub 2014 Apr 9.
• The inherited prion diseases (IPD) are a group of untreatable neurodegenerative diseases that segregate as autosomal dominant traits. Mutations in the prion protein gene (PRNP) were first found to be causal of IPD in 1989, before the molecular genetic characterisation of any other neurodegenerative
• PMID 24713662

• MEK1 transduces the prion protein N2 fragment antioxidant effects.

• Haigh CL1, McGlade AR, Collins SJ.
• Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2014 Nov 13. [Epub ahead of print]
• The prion protein (PrPC) when mis-folded is causally linked with a group of fatal neurodegenerative diseases called transmissible spongiform encephalopathies or prion diseases. PrPC normal function is still incompletely defined with such investigations complicated by PrPC post-translational modifica
• PMID 25391659

• Involvement of Trace Elements in the Pathogenesis of Prion Diseases.

• Mizuno D, Koyama H, Ohkawara S, Sadakane Y, Kawahara M1.
• Current pharmaceutical biotechnology.Curr Pharm Biotechnol.2014 Nov 2. [Epub ahead of print]
• Prion diseases are progressive neurodegenerative diseases that are associated with conformational changes that convert normal cellular prion protein (PrPC) into an abnormal pathogenic prion protein (PrPSc). It is widely recognized that prion diseases are forms of transmissible amyloidosis and are co
• PMID 25373386

Japanese Journal

• Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress

• Microbiology and immunology 58(7), 361-374, 2014-07
• NAID 40020130152

• Absence of CD14 Delays Progression of Prion Diseases Accompanied by Increased Microglial Activation

• Journal of Virology 87(24), 13433-13445, 2013-12
• NAID 120005455879

• Intestinal Transmission of Prions and Role of Exosomes in Enterocytes

• Food Safety 1(1), 2013005-2013005, 2013
• NAID 130004591215

Related Links

• Prion protein scrapie and the normal cellular prion protein

Furthermore, the structure and function of the normal cellular prion protein (PrP C) and its importance in not only in prion disease development, but also in diseases such as cancer and Alzheimer's disease will also be discussed.

• PRNP gene - Genetics Home Reference - NIH

PRNP gene prion protein Printable PDF Open All Close All Normal Function The PRNP gene provides instructions for making a protein called prion protein (PrP), which is active in the brain and several other tissues. Although the ...

• The Cellular Prion Protein (PrPC): Its Physiological Function ...

The Cellular Prion Protein (PrP C): Its Physiological Function and Role in Disease Laura Westergard , 1 Heather M. Christensen , 1 and David A. Harris * Department of Cell Biology and Physiology, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110

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★リンクテーブル★

リンク元	「PrP-sen」「PrPC protein」「正常プリオンタンパク質」
関連記事	「normal」「norm」「prion protein」

「PrP-sen」

　　[★]

正常プリオンタンパク質

関

normal prion protein、PrPC protein

「PrPC protein」

　　[★]

• 正常プリオンタンパク質

関

normal prion protein、PrP-sen

「正常プリオンタンパク質」

　　[★]

英

normal prion protein、PrPC protein、PrP-sen

「normal」

　　[★]

• adj.

• 正常な、正常型の、普通の、通常の、(統計)正規の、(化学)規定濃度、直鎖状の、(直鎖状の)ノルマル

関

common、commonly、conventional、general、generally、in general、linear、N、n-、normally、ordinarily、ordinary、straight、usual、usually

　 　 　 　 　

「norm」

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• n.

• 規範。標準、平均。基準生産高/労働量、ノルマ。(教育)(集団または個人の)平均成績/学力。(特定人間集団の)典型的行動様式。普通のこと。(数)ノルム。(地学)ノルム

　 　

「prion protein」

　　[★]

同

PrP

同

PrP

同

PrP