伝播性筋放電群
WordNet
- complicated in structure; consisting of interconnected parts; "a complex set of variations based on a simple folk melody"; "a complex mass of diverse laws and customs"
- a compound described in terms of the central atom to which other atoms are bound or coordinated (同)coordination_compound
- a conceptual whole made up of complicated and related parts; "the complex of shopping malls, houses, and roads created a new town" (同)composite
- (psychoanalysis) a combination of emotions and impulses that have been rejected from awareness but still influence a persons behavior
PrepTutorEJDIC
- 『いくつかの部分から成る』,複合の,合成の / 『複雑な』,入りくんだ,こみいった(complicated) / 複合体,合成物 / コンプレックス,複合(抑圧されて心に残った複雑なしこり)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/12 23:51:41」(JST)
[Wiki en表示]
Migrating motor complexes (or migrating myoelectric complex or migratory motor complex or migratory myoelectric complex or MMC) are waves of electrical activity that sweep through the intestines in a regular cycle during fasting. These motor complexes trigger peristaltic waves, which facilitate transportation of indigestible substances such as bone, fiber, and foreign bodies from the stomach, through the small intestine, past the ileocecal sphincter, and into the colon. The MMC occurs every 90-120 minutes during the interdigestive phase (between meals), and is responsible for the rumbling experienced when hungry.[1] It also serves to transport bacteria from the small intestine to the large intestine, and to inhibit the migration of colonic bacteria into the terminal ileum.
Contents
- 1 Phases
- 2 Regulation
- 3 Stimuli
- 4 References
- 5 External links
Phases
The MMC originates mostly in the stomach — although ~25% will arise from the duodenum or proximal jejunum — and can travel to the distal end of the ileum.[2] They consist of four distinct phases: Phase I — A prolonged period of quiescence; Phase II — Increased frequency of action potentials and smooth muscle contractility; Phase III — A few minutes of peak electrical and mechanical activity, and; Phase IV — Declining activity which merges with the next Phase I.[3]
Regulation
The MMC is thought to be partially regulated by motilin, which is initiated in the stomach as a response to vagal stimulation, and does not directly depend on extrinsic nerves.
Stimuli
Morphine, has been found at relatively low doses to stimulate phase III of the migrating motor complex.[4]
Trimebutine is one drug that as part of its therapeutic action causes a premature activation of phase III of the migrating motor complex in the digestive tract.[5]
References
- ^ Poitras, P. & Peeters, T.L., 2008. Motilin. Current Opinion in Endocrinology, Diabetes, and Obesity, 15(1), pp.54–57.
- ^ Boron, Walter F. & Emile L. Boulpaep, 2012. Medical Physiology, 2e Updated Edition: with STUDENT CONSULT Online Access, 2e 2 edition., Philadelphia, PA: Saunders.
- ^ Boron, Walter F. & Emile L. Boulpaep, 2012. Medical Physiology, 2e Updated Edition: with STUDENT CONSULT Online Access, 2e 2 edition., Philadelphia, PA: Saunders.
- ^ Lewis, TD. (Nov 1999). "Morphine and gastroduodenal motility.". Dig Dis Sci 44 (11): 2178–86. PMID 10573360.
- ^ Hiyama, T.; Yoshihara, M.; Tanaka, S.; Haruma, K.; Chayama, K. (Apr 2009). "Effectiveness of prokinetic agents against diseases external to the gastrointestinal tract." (PDF). J Gastroenterol Hepatol 24 (4): 537–46. doi:10.1111/j.1440-1746.2009.05780.x. PMID 19220673.
- http://medical-dictionary.thefreedictionary.com/migrating+myoelectric+complex
External links
- Overview at colostate.edu
- Physiology: 6/6ch2/s6ch2_26 - Essentials of Human Physiology
- Migrating motor complex at the US National Library of Medicine Medical Subject Headings (MeSH)
Physiology of the gastrointestinal system
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GI tract |
Upper |
Exocrine |
- Chief cells
- Parietal cells
- Gastric acid
- Intrinsic factor
- Foveolar cells
- Goblet cells
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Processes |
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Fluids |
|
|
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Lower |
Enteric nervous system |
- Submucous plexus
- Myenteric plexus
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Endocrine/paracrine |
- G cells
- D cells
- ECL cells
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enterogastrone: |
|
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- Enteroendocrine cells
- Enterochromaffin cell
- APUD cell
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|
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Fluids |
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|
Processes |
- Segmentation contractions
- Migrating motor complex
- Borborygmus
- Defecation
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|
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Either/both |
Processes |
- Peristalsis (Interstitial cell of Cajal
- Basal electrical rhythm)
- Gastrocolic reflex
- Digestion
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|
|
|
Accessory |
Fluids |
|
|
Processes |
- Enterohepatic circulation
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|
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Abdominopelvic |
|
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UpToDate Contents
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English Journal
- Long-term culture and cryopreservation of interstitial cells of Cajal.
- Xu WD, Jiang X, Lan L, Wang CH, Tong HX, Wang BX.SourceDepartment of Pediatrics, Tangdu Hospital , Fourth Military Medical University, Xi'an, Shanxi Province , China.
- Scandinavian journal of gastroenterology.Scand J Gastroenterol.2011 Nov 4. [Epub ahead of print]
- Abstract Objective. Interstitial cells of Cajal (ICCs) in the gastrointestinal tract generate and propagate slow waves and mediate neuromuscular neurotransmission. Damage to ICCs has been described in several gastrointestinal motor disorders, and although many studies have examined ICCs in cult
- PMID 22050097
- Involvement of neuronal nitric oxide synthase (nNOS) in the regulation of migrating motor complex (MMC) in sheep.
- Castro M, Muñoz JM, Arruebo MP, Murillo MD, Arnal C, Bonafonte JI, Plaza MA.SourceDepartamento de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Zaragoza, Miguel Servet, 177, 50013 Zaragoza, Spain.
- Veterinary journal (London, England : 1997).Vet J.2011 Oct 12. [Epub ahead of print]
- The objectives of this study were to evaluate the role of nitric oxide (NO) synthase isoforms (nNOS, eNOS, and iNOS) in the regulation of the migrating motor complex (MMC) in sheep using electromyography and their expression in the gastrointestinal (GI) tract by Western blot (WB) and immunohistochem
- PMID 21995890
Japanese Journal
- 意識下の成犬におけるブドウ糖・アミノ酸・脂肪乳剤および食塩水の空腸内への持続投与が消化管運動と門脈血流におよぼす影響
- Changes of Intestinal Motility after Massive Small Bowel Resection with a Reversed Jejunal Segment.
- Migrating myoelectric complex and jejunal slow-wave propagation after Roux gastrectomy in dogs
Related Links
- The MMC originates in the stomach roughly every 75 to 90 minutes during the interdigestive phase (between meals) and is ... The MMC is thought to be partially regulated by motilin, which is initiated in the stomach as a response to vagal ...
Related Pictures
![Myoelectric Complex, Migrating (Migrating](https://1mg.info/0/8/p/0875.jpg)
![migrating myoelectric complex travels](https://1mg.info/0/8/p/0877.jpg)
![Myoelectric Complex, Migrating (Migrating](https://1mg.info/0/8/p/0878.jpg)
![Myoelectric Complex, Migrating; Migrating](https://1mg.info/0/8/p/0879.jpg)
![Myoelectric Complex, Migrating](https://1mg.info/0/8/p/0880.jpg)
★リンクテーブル★
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- 英
- migrating myoelectric complex
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- 関
- complexes、complicated、composite、conjugate、intricate
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- 関
- hybrid、mixed lineage、mixed type、mixed-type
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- 関
- locomotive、migratory、mobile、mobility
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- 関
- complex、composite