間葉
- 関
- dorsal mesoderm、intermediate mesoderm、lateral plate mesoderm、mesenchymal、mesenchyme、mesoderm、paraxial mesoderm
WordNet
- mesodermal tissue that forms connective tissue and blood and smooth muscles
- the middle germ layer that develops into muscle and bone and cartilage and blood and connective tissue (同)mesoblast
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/01/12 19:11:11」(JST)
[Wiki en表示]
Mesenchyme |
Transmission electron micrograph of mesenchyme displaying the ultrastructure of a typical cell and matrix.
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Mesenchyme (pointer) stained with H&E
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Details |
Latin |
mesenchyma |
Carnegie stage |
6b |
Precursor |
primarily mesoderm |
Identifiers |
Code |
TE E5.16.4.0.3.0.18 |
Anatomical terminology |
Mesenchyme is a type of tissue characterized by loosely associated cells that lack polarity and are surrounded by a large extracellular matrix. Mesenchymal cells are able to develop into the tissues of the lymphatic and circulatory systems, as well as connective tissues throughout the body, such as bone and cartilage. A sarcoma is a malignant cancer of mesenchymal cells.[1][2]
Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibrils and unspecialized cells.[3] Mesenchymal cells can migrate easily, in contrast to epithelial cells, which lack mobility and are organized into closely adherent sheets, and are polarized in an apical-basal orientation.
See also
- Ectomesenchyme
- Splanchnopleuric mesenchyme
- Somatopleuric mesenchyme
- Intramembranous ossification
- Mesenchymal stem cell
- Mesoderm
- Mesohyl, the gelatinous matrix in sponges, formerly called mesenchyme
- Epithelial–mesenchymal transition
References
- ^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstown, MD: Lippincott Williams & Wilkins. p. 83. ISBN 0-7817-8577-4.
- ^ Sadler, T.W. (2006). Langman's Medical Embryology. Lippincott Williams & Wilkins. pp. 68–70. ISBN 0-7817-9485-4.
- ^ Mesenchymal tissue
External links
- Overview at University of Edinburgh
Connective tissue
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Physiology |
- Soft tissue
- Fibrosis
- Scarring
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Composition |
Cells |
Resident |
- Fibroblast
- Fibrocyte
- Reticular cell
- Tendon cell
- Adipocyte
- Melanocyte
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Wandering cells |
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Extracellular
matrix |
Ground substance |
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Fibers |
- Collagen fibers
- Reticular fibers: COL3A1
- Elastic fibers: Elastin
- Fibrillin
- EMILIN1
- Elaunin
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Classification |
Proper |
Loose |
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Dense |
- Dense irregular connective tissue
- Dense regular connective tissue
- Ligament
- Tendon
- Aponeurosis
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Embryonic |
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Specialized |
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Index of skin
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
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Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
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Index of muscle
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Description |
- Anatomy
- head
- neck
- arms
- chest and back
- diaphragm
- abdomen
- genital area
- legs
- Muscle tissue
- Physiology
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Disease |
- Myopathy
- Soft tissue
- Connective tissue
- Congenital
- abdomen
- muscular dystrophy
- Neoplasms and cancer
- Injury
- Symptoms and signs
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Treatment |
- Procedures
- Drugs
- anti-inflammatory
- muscle relaxants
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UpToDate Contents
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English Journal
- PHACE syndrome - clinical features, aetiology and management.
- Winter PR1, Itinteang T1, Leadbitter P1,2,3, Tan ST1,2.
- Acta paediatrica (Oslo, Norway : 1992).Acta Paediatr.2016 Feb;105(2):145-53. doi: 10.1111/apa.13242. Epub 2015 Nov 27.
- PHACE syndrome comprises a spectrum of anomalies including posterior fossa malformations, haemangioma, arterial anomalies, cardiac defects and eye anomalies. PHACE should be considered in any patient with a large facial segmental infantile haemangioma (IH), and multidisciplinary management is crucia
- PMID 26469095
- Investigating the effect of excess caffeine exposure on placental angiogenesis using chicken 'functional' placental blood vessel network.
- Ma ZL1, Wang G1, Lu WH1, Cheng X1, Chuai M2, Lee KK3, Yang X1.
- Journal of applied toxicology : JAT.J Appl Toxicol.2016 Feb;36(2):285-95. doi: 10.1002/jat.3181. Epub 2015 Jul 14.
- It is now known that over-consumption of caffeine by pregnant mothers could have detrimental effects on normal fetal development. However, it remains obscure how caffeine's harmful effect impacts directly or indirectly on the developing embryo/fetus through damaging placenta development. In this stu
- PMID 26179615
- Recombinant Xeno-Free Vitronectin Supports Self-Renewal and Pluripotency in Protein-Induced Pluripotent Stem Cells.
- Kaini RR1, Shen-Gunther J2, Cleland JM1, Greene WA1, Wang HC1.
- Tissue engineering. Part C, Methods.Tissue Eng Part C Methods.2016 Jan 15. [Epub ahead of print]
- Patient safety is a major concern in the application of induced pluripotent stem cells (iPSCs) in cell-based therapy. Efforts are being made to reprogram, maintain, and differentiate iPSCs in defined conditions to provide a safe source of stem cells for regenerative medicine. Recently, human fibrobl
- PMID 26581311
Japanese Journal
- Immunohistochemical Characteristics of Odontogenic Neoplasms and Their Physiological Counterparts
- Nakano Keisuke,Nagatsuka Hitoshi,Tsujigiwa Hidetsugu [他],Gunduz Mehmet,Katase Naoki,Siar Chong Huat,Kawakami Toshiyuki
- Journal of hard tissue biology 17(3), 79-90, 2008-12
- … For dental doctors, interest is particularly high, because the tooth is mainly composed of surface ectodermal epithelium and neural crest derived neuroectodermal mesenchyma, and formed by epithelial-mesenchymal interactions. …
- NAID 110007081308
- A histopathological and immunohistochemical study of cell adhesion factors in pleomorphic adenoma: mesenchyma-like changes of epithelial tumor cells
- Anzai Hisae
- Oral Medicine & Pathology 12(2), 35-45, 2008
- … The purposes of this study were to clarify morphological characteristics of tissue diversity of salivary pleomorphic adenomas (PA), and to examined cell adhesion and formation of mesenchyma-like tissue using histopathological and immunohistochemical methods. …
- NAID 130004850519
- Immunohistochemical Characteristics of Odontogenic Neoplasms and Their Physiological Counterparts
- Nakano Keisuke,Nagatsuka Hitoshi,Tsujigiwa Hidetsugu,Gunduz Mehmet,Katase Naoki,Siar Chong Huat,Kawakami Toshiyuki
- Journal of Hard Tissue Biology 17(3), 79-90, 2008
- … For dental doctors, interest is particularly high, because the tooth is mainly composed of surface ectodermal epithelium and neural crest derived neuroectodermal mesenchyma, and formed by epithelial-mesenchymal interactions. …
- NAID 130004848334
Related Links
- mesenchyma /mes·en·chy·ma/ (mez-eng?kĭ-mah) mesenchyme. mesenchyma [mĕ-seng´kĭ-mah] the meshwork of embryonic connective tissue in the mesoderm; from it are formed the connective tissues of the body as well as blood ...
- [FIGURE 1 OMITTED] [FIGURE 2 OMITTED] The heart is developed from the cardiac mesenchyma, which is characterized by the expression of cardiac specific transcription factor NKX2-5 (21, 39, 40). Sequence variations of NKX2-5 ...
Related Pictures
★リンクテーブル★
[★]
背側中胚葉、背部中胚葉
- 関
- dorsal mesodermal、intermediate mesoderm、lateral plate mesoderm、mesenchyma、mesenchyme、mesoderm、paraxial mesoderm
[★]
- 関
- mesenchyma、mesenchyme
[★]
- 同
- GIMT
- 関
- 粘膜下腫瘍
- 消化管粘膜下腫瘍の一つで、平滑筋系や神経系由来の紡錘形腫瘍をも含む包括的な診断概念。
- 間葉系腫瘍 gastrointestinal mesenchymal tumor GIMT : 広義のGISTと主張する人もいる
- GIST:CD34(+), c-Kit(+) → 粘膜下腫瘍の中で最多である。
- 筋原性腫瘍:平滑筋腫、平滑筋肉腫、類上皮平滑筋肉腫:smooth muscle actin(+), desmin(+)
- 神経原性腫瘍:神経鞘腫、神経線維腫:S-100(+)
参考
- http://www.nmckk.jp/pdf.php?mode=book&bookkey=b0549&filename=b0549_188_195.pdf
[★]
[★]
- 関
- primary mesenchyme