WordNet

mesodermal tissue that forms connective tissue and blood and smooth muscles

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/04/08 14:38:35」(JST)

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Mesenchyme

Mesenchyme showing a typical cell and matrix.

Mesenchyme (pointer) stained with H&E
Latin	mesenchyma
Carnegie stage	6b
Precursor	primarily mesoderm
Code	TE E5.16.4.0.3.0.18

Mesenchyme, or mesenchymal connective tissue, is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm, although some are derived from other germ layers; e.g. some mesenchyme is derived from neural crest cells and thus originates from the ectoderm. In fact, most embryologists use the term mesenchyme only for those cells that develop from the mesoderm. The term mesenchyme essentially refers to the morphology of embryonic cells. Mesenchymal cells can migrate easily, unlike epithelial cells, which do not show great mobility and which are polygonal in shape, polarized in an apical-basal orientation, and organized into closely adherent sheets. Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibrils and unspecialized cells.^[1] The cells are capable of developing into connective tissue, such as bone, and cartilage, the lymphatic system, and the circulatory system.^[2]^[3]

References

^ Mesenchymal tissue
^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstwon, MD: Lippincott Williams & Wilkins. pp. 83. ISBN 0-7817-8577-4.
^ Sadler, T.W. (2006). Langman's Medical Embryology. Lippincott Williams & Wilkins. pp. 68–70. ISBN 0-7817-9485-4.

External links

Overview at University of Edinburgh

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1. 歯の解剖学的構造および発達 anatomy and development of the teeth
2. 先天性中胚葉性腎腫の出生前診断 prenatal diagnosis of congenital mesoblastic nephroma
3. 新生児における呼吸促迫症候群の病態生理および臨床症状 pathophysiology and clinical manifestations of respiratory distress syndrome in the newborn
4. 腎発育不全 renal hypoplasia
5. 耳の先天異常 congenital anomalies of the ear

English Journal

Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development.

Opitz R, Maquet E, Huisken J, Antonica F, Trubiroha A, Pottier G, Janssens V, Costagliola S.SourceInstitute of Interdisciplinary Research in Molecular Human Biology (IRIBHM), Université Libre de Bruxelles, Route de Lennik 808, 1070 Brussels, Belgium.
Developmental biology.Dev Biol.2012 Dec 15;372(2):203-16. doi: 10.1016/j.ydbio.2012.09.011. Epub 2012 Sep 26.
Among the various organs derived from foregut endoderm, the thyroid gland is unique in that major morphogenic events such as budding from foregut endoderm, descent into subpharyngeal mesenchyme and growth expansion occur in close proximity to cardiovascular tissues. To date, research on thyroid orga
PMID 23022354

FGF signaling transforms non-neural ectoderm into neural crest.

Yardley N, García-Castro MI.SourceDepartment of Molecular, Cellular, and Developmental Biology, KBT 1100, Yale University, P.O. Box 208103, New Haven, CT 06520-8103, USA.
Developmental biology.Dev Biol.2012 Dec 15;372(2):166-77. doi: 10.1016/j.ydbio.2012.09.006. Epub 2012 Sep 19.
The neural crest arises at the border between the neural plate and the adjacent non-neural ectoderm. It has been suggested that both neural and non-neural ectoderm can contribute to the neural crest. Several studies have examined the molecular mechanisms that regulate neural crest induction in neura
PMID 23000357

Japanese Journal

アフリカツメガエル Xenopus laevis と洞窟魚 Astyanax mexicanus の初期発生に対する Sonic hedgehog 経路阻害剤 SANT-I 投与の影響

前田真実,Maeda Manami,茂木和枝,Mogi Kazue,小林剛,Kobayashi Tsuyoshi,日野晶也,Hino Akiya,豊泉龍児,Toyoizumi Ryuji
Science Journal of Kanagawa University 24, 69-75, 2013-06-30
… 原著　2012年度神奈川大学総合理学研究所共同研究助成論文Sonic hedgehog (Shh) is a peptide growth factor, belonging to the Hedgehog family.Shh is expressed in various embryonic tissues, such as the notochord, floor plate, and posteriorlimb-bud mesenchyme, and plays versatile roles in early axis specification and organogenesis.For example, shh is involved in the dorso-ventral patterning of the neural tube and inthe antero-posterior patterning of the limb bud. …
NAID 120005302537

Expression of the IGF-1, IGFBP-3 and IGF-1 receptors in dental pulp stem cells and impacted third molars

Magnucki Gabriel,Schenk Ulf,Ahrens Stefan,Navarrete Santos Alexander,R. Gernhardt Christian,Schaller Hans-Günter,Hoang-Vu Cuong
Journal of Oral Science 55(4), 319-327, 2013
… The major sources of all of the proteins investigated immunohistochemically in sections of wisdom teeth were odontoblasts, cementoblasts and cell colonies in the pulpal mesenchyme. …
NAID 130003383949

Spontaneous Ameloblastic Fibroma in a Young Guinea Pig

TANAKA Makoto,SAWAMOTO Osamu
Journal of Toxicologic Pathology 26(3), 325-328, 2013
… Histopathologically, neoplastic cells consisted of two components: an odontogenic epithelium and odontogenic mesenchyme. … The odontogenic epithelium formed strands, nests and islands that were interspersed within the odontogenic mesenchyme. … Immunohistochemically, the odontogenic epithelium was positive for cytokeratin AE1/AE3, and the odontogenic mesenchyme and odontoblast were positive for vimentin, in the same manner as in the normal tooth germ (control). …
NAID 130003382452

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★リンクテーブル★

リンク元	「dorsal mesoderm」「間充織」「mesenchyma」「間葉組織」「mesenchymal」
拡張検索	「secondary mesenchyme」「primary mesenchyme」