- 関
- mesenchyma、mesenchyme
WordNet
- mesodermal tissue that forms connective tissue and blood and smooth muscles
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/08/31 17:54:33」(JST)
[Wiki en表示]
Mesenchyme |
|
Mesenchyme showing a typical cell and matrix. |
|
Mesenchyme (pointer) stained with H&E |
Latin |
mesenchyma |
Carnegie stage |
6b |
Precursor |
primarily mesoderm |
Code |
TE E5.16.4.0.3.0.18 |
Mesenchyme, also called mesenchymal connective tissue, is a type of undifferentiated loose connective tissue that is derived mostly from mesoderm, although some is derived from other germ layers; e.g. neural crest cells and thus originates from the ectoderm. Most embryologists use the term "mesenchyme" only for those cells that develop from the mesoderm.[citation needed]
The term mesenchyme essentially refers to the morphology of embryonic cells, however, they do persist as stem cells into adulthood. Mesenchymal cells are able to develop into the tissues of the lymphatic and circulatory systems, as well as connective tissues throughout the body, such as bone and cartilage. A sarcoma is a cancer of mesenchymal cells.[1][2]
Mesenchyme is characterized morphologically by a prominent ground substance matrix containing a loose aggregate of reticular fibrils and unspecialized cells.[3] Mesenchymal cells can migrate easily, in contrast to epithelial cells, which lack mobility and are organized into closely adherent sheets, are polygonal in shape, and are polarized in an apical-basal orientation.
See also[edit source | edit]
- Ectomesenchyme
- Splanchnopleuric mesenchyme
- Somatopleuric mesenchyme
- Intramembranous ossification
- Mesenchymal stem cell
- Mesoderm
- Mesohyl, the gelatinous matrix in sponges, formerly called mesenchyme
- Epithelial–mesenchymal transition
References[edit source | edit]
- ^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 83. ISBN 0-7817-8577-4.
- ^ Sadler, T.W. (2006). Langman's Medical Embryology. Lippincott Williams & Wilkins. pp. 68–70. ISBN 0-7817-9485-4.
- ^ Mesenchymal tissue
External links[edit source | edit]
- Overview at University of Edinburgh
Connective Tissue (TH H2.00.03)
|
|
Physiology |
- Soft tissue
- Fibrosis
- Scarring
|
|
Classification |
Connective tissue proper |
Loose |
|
|
Dense |
- Dense irregular connective tissue
- Dense regular connective tissue
- Ligament
- Tendon
- Aponeurosis
|
|
|
Embryonic |
|
|
Specialized |
|
|
|
Composition (Histology) |
Cells |
Resident |
- Fibroblast
- Fibrocyte
- Reticular cell
- Tendon cell
|
|
Wandering
cell |
|
|
|
Extracellular
matrix
(noncellular) |
Ground substance |
|
|
Fibers |
- Elastic fibers: Elastin
- Fibrillin
- EMILIN1
|
|
|
|
See also: Template:Soft tissue tumors and sarcomas
|
|
noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon
|
proc, drug (D2/3/4/5/8/11)
|
|
|
anat (h/n, u, t/d, a/p, l)/phys/devp/hist
|
noco (m, s, c)/cong (d)/tumr, sysi/epon, injr
|
|
|
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Effects of canola proteins and hydrolysates on adipogenic differentiation of C3H10T/2 mesenchymal stem cells.
- Alashi AM1, Blanchard CL2, Mailer RJ3, Agboola SO4, Mawson AJ4, Aluko RE5, Strappe P2.
- Food chemistry.Food Chem.2015 Oct 15;185:226-32. doi: 10.1016/j.foodchem.2015.03.054. Epub 2015 Mar 27.
- This study assessed the ability of canola protein isolate (CPI) and enzymatic hydrolysates (CPHs) to inhibit adipogenic differentiation of C3H10T1/2 murine mesenchymal stem cells in vitro. Cell viability was maintained at concentrations of 60μg/ml of sample. Cells treated with Alcalase hydrolysate
- PMID 25952862
- New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.
- Salomon-Kent R1,2, Marom R1,2, John S2, Dundr M2, Schiltz LR2, Gutierrez J3, Workman J3, Benayahu D1, Hager GL2.
- Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2270-80. doi: 10.1002/jcp.24960.
- Mesenchymal stem cells' differentiation into several lineages is coordinated by a complex of transcription factors and co-regulators which bind to specific gene promoters. The Chromatin-Related Mesenchymal Modulator, CHD9 demonstrated in vitro its ability for remodeling activity to reposition nucleo
- PMID 25689118
- Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits.
- Qin L1, Yao D2, Zheng L2, Liu WC2, Liu Z2, Lei M3, Huang L2, Xie X2, Wang X4, Chen Y5, Yao X6, Peng J7, Gong H8, Griffith JF9, Huang Y10, Zheng Y10, Feng JQ11, Liu Y11, Chen S2, Xiao D3, Wang D5, Xiong J5, Pei D12, Zhang P13, Pan X14, Wang X15, Lee KM16, Cheng CY2.
- Biomaterials.Biomaterials.2015 Aug;59:125-43. doi: 10.1016/j.biomaterials.2015.04.038. Epub 2015 May 15.
- Steroid-associated osteonecrosis (SAON) may lead to joint collapse and subsequent joint replacement. Poly lactic-co-glycolic acid/tricalcium phosphate (P/T) scaffold providing sustained release of icaritin (a metabolite of Epimedium-derived flavonoids) was investigated as a bone defect filler after
- PMID 25968462
Japanese Journal
- Autologous Bone-Marrow Mesenchymal Stem Cell Implantation and Endothelial Function in a Rabbit Ischemic Limb Model
- Mikami Shinsuke,Nakashima Ayumu,Nakagawa Keigo,Maruhashi Tatsuya,Iwamoto Yumiko,Kajikawa Masato,Matsumoto Takeshi,Kihara Yasuki,Chayama Kazuaki,Noma Kensuke,Ochi Mitsuo,Nishimura Masahiro,Tsuji Koichiro,Kato Yukio,Goto Chikara,Higashi Yukihito
- PLoS ONE 8(7), e67739, 2013-07-04
- … Background:The purpose of this study was to determine whether autologous mesenchymal stem cells (MSCs) implantation improves endothelial dysfunction in a rabbit ischemic limb model.Methods:We evaluated the effect of MSC implantation on limb blood flow (LBF) responses to acetylcholine (ACh), an endothelium-dependent vasodilator, and sodium nitroprusside (SNP), an endothelium-independent vasodilator, in rabbits with limb ischemia in which cultured MSCs were implanted (n = 20) or saline was injected as a control group (n = 20). …
- NAID 120005311939
- Dlg5 interacts with the TGF-β receptor and promotes its degradation.
- Sezaki Takuhito,Tomiyama Lucia,Kimura Yasuhisa,Ueda Kazumitsu,Kioka Noriyuki
- FEBS letters 587(11), 1624-1629, 2013-06-05
- … Discs large homolog 5 (Dlg5) is a member of the membrane-associated guanylate kinase adaptor family of proteins and is involved in epithelial-to-mesenchymal transition via transforming growth factor-β (TGF-β) signaling. …
- NAID 120005293584
- Electrofusion of Mesenchymal Stem Cells and Islet Cells for Diabetes Therapy: A Rat Model
- Yanai Goichi,Hayashi Takashi,Zhi Qi,Yang Kai-Chiang,Shirouzu Yasumasa,Shimabukuro Takashi,Hiura Akihito,Inoue Kazutomo,Sumi Shoichiro
- PLoS ONE 8(5), 2013-05-28
- … In contrast, mesenchymal stem cells (MSCs) are highly proliferative, anti-apoptotic and pluripotent to differentiate toward various cell types, promote angiogenesis and modulate inflammation, thereby studied as an enhancer of islet function and engraftment. …
- NAID 120005245076
Related Links
- mes·en·chyme (mĕz′ən-kīm′, mĕs′-) n. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground ... Our work revealed that patient-derived mesenchymal niche cells are ...
- Seen and Heard What made you want to look up mesenchymal? Please tell us where you read or heard it (including the quote, if possible).
Related Pictures
★リンクテーブル★
[★]
- 英
- mesenchyme、mesenchymal
- 関
- 沿軸中胚葉、間葉、側板中胚葉、中間中胚葉、中胚葉、背側中胚葉、間葉系、間葉組織
[★]
- 英
- mesenchymal
- 関
- 間充織、間葉
[★]
- 同
- GIMT
- 関
- 粘膜下腫瘍
- 消化管粘膜下腫瘍の一つで、平滑筋系や神経系由来の紡錘形腫瘍をも含む包括的な診断概念。
- 間葉系腫瘍 gastrointestinal mesenchymal tumor GIMT : 広義のGISTと主張する人もいる
- GIST:CD34(+), c-Kit(+) → 粘膜下腫瘍の中で最多である。
- 筋原性腫瘍:平滑筋腫、平滑筋肉腫、類上皮平滑筋肉腫:smooth muscle actin(+), desmin(+)
- 神経原性腫瘍:神経鞘腫、神経線維腫:S-100(+)
参考
- http://www.nmckk.jp/pdf.php?mode=book&bookkey=b0549&filename=b0549_188_195.pdf
[★]
[★]
- 関
- primary mesenchyme
[★]
間葉
- 関
- dorsal mesoderm、intermediate mesoderm、lateral plate mesoderm、mesenchymal、mesenchyme、mesoderm、paraxial mesoderm