WordNet

malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood

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白血病

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1. 急性骨髄性白血病の分類 classification of acute myeloid leukemia
2. 小児や青年の急性リンパ芽球性白血病の転帰に関する概要 overview of the outcome of acute lymphoblastic leukemia in children and adolescents
3. 急性リンパ芽球性白血病における細胞遺伝学および分子遺伝学 cytogenetics and molecular genetics in acute lymphoblastic leukemia
4. 急性骨髄性白血病の合併症の概要 overview of the complications of acute myeloid leukemia
5. 慢性リンパ性白血病に対する治療の概要 overview of the treatment of chronic lymphocytic leukemia

English Journal

Congenital acute megakaryoblastic leukemia.

Bain BJ1,2, Chakravorty S2, Ancliff P3.
American journal of hematology.Am J Hematol.2015 Oct;90(10):963. doi: 10.1002/ajh.24109. Epub 2015 Sep 1.
PMID 26148249

Mechanism of irradiation-induced mammary cancer metastasis: A role for SAP-dependent Mkl1 signaling.

Asparuhova MB1, Secondini C2, Rüegg C3, Chiquet-Ehrismann R4.
Molecular oncology.Mol Oncol.2015 Oct;9(8):1510-27. doi: 10.1016/j.molonc.2015.04.003. Epub 2015 Apr 30.
Radiotherapy is a standard treatment after conservative breast cancer surgery. However, cancers relapsing within a previously irradiated area have an increased probability to metastasize. The mechanisms responsible for this aggressiveness remain unclear. Here, we used the clinically relevant 4T1 bre
PMID 25999144

Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.

Record J1, Malinova D1, Zenner HL2, Plagnol V3, Nowak K1, Syed F1, Bouma G1, Curtis J2, Gilmour K4, Cale C4, Hackett S5, Charras G6, Moulding D1, Nejentsev S2, Thrasher AJ7, Burns SO8.
Blood.Blood.2015 Sep 24;126(13):1527-35. doi: 10.1182/blood-2014-12-611012. Epub 2015 Jul 29.
Megakaryoblastic leukemia 1 (MKL1), also known as MAL or myocardin-related transcription factor A (MRTF-A), is a coactivator of serum response factor, which regulates transcription of actin and actin cytoskeleton-related genes. MKL1 is known to be important for megakaryocyte differentiation and func
PMID 26224645

Related Links

The biology of pediatric acute megakaryoblastic leukemia.

1. Blood. 2015 Aug 20;126(8):943-9. doi: 10.1182/blood-2015-05-567859. Epub 2015 Jul 17. The biology of pediatric acute megakaryoblastic leukemia. Gruber TA(1), Downing JR(2). Author information: (1)Department of ...

Leukemia - NUP98/JARID1A is a novel recurrent abnormality ...

NUP98 / JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern J D E de Rooij 1, I H I M Hollink 1, S T C J M Arentsen-Peters 1, J F van Galen 2, 2 3 4 ...