WordNet

malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood
of or pertaining to large bone marrow cells

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1. 急性骨髄性白血病の分類 classification of acute myeloid leukemia
2. 巨核球の生物学と血小板の産生 megakaryocyte biology and the production of platelets
3. 先天性角化異常症とその他の短縮テロメア症候群 dyskeratosis congenita and other short telomere syndromes
4. ダウン症候群の一過性骨髄増殖性疾患 transient myeloproliferative disorder of down syndrome
5. 骨髄穿刺塗抹標本の評価 evaluation of bone marrow aspirate smears

The AS-RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation.

Tran NT1, Su H1, Khodadadi-Jamayran A1, Lin S2, Zhang L1, Zhou D1, Pawlik KM1, Townes TM1, Chen Y3, Mulloy JC4, Zhao X5.
EMBO reports.EMBO Rep.2016 Apr 26. pii: e201541970. [Epub ahead of print]
Antisense RNAs regulate the transcription and translation of the corresponding sense genes. Here, we report that an antisense RNA, AS-RBM15, is transcribed in the opposite direction within exon 1 of RBM15 RBM15 is a regulator of megakaryocyte (MK) differentiation and is also involved in a chromosome
PMID 27118388

Recurrent genetic abnormalities can be used for risk-group stratification in pediatric AMKL: results of a retrospective intergroup study.

de Rooij JD1, Masetti R2, van den Heuvel-Eibrink MM3, Cayuela JM4, Trka J5, Reinhardt D6, Rasche M6, Sonneveld E7, Alonzo TA8, Fornerod M1, Zimmermann M9, Pigazzi M10, Pieters R3, Meshinchi S11, Zwaan CM12, Locatelli F13.
Blood.Blood.2016 Apr 25. pii: blood-2016-01-695551. [Epub ahead of print]
Genetic abnormalities and early treatment response are the main prognostic factors in acute myeloid leukemia (AML). Acute megakaryoblastic leukemia (AMKL) is a rare subtype of AML. Deep sequencing has identified CBFA2T3/GLIS2 and NUP98/KDM5A as recurrent aberrations, occurring in similar frequencies
PMID 27114462

Leukemia cell infiltration causes defective erythropoiesis partially through MIP-1α/CCL3.

Wang Y1, Gao A1, Zhao H1, Lu P1, Cheng H1,2, Dong F1, Gong Y1, Ma S1, Zheng Y1, Zhang H1, Zhang Y1, Xu J1, Zhu X1,2,3, Yuan W1,2,3, Zhang X1,3,4, Hao S1, Cheng T1,2,3.
Leukemia.Leukemia.2016 Apr 25. doi: 10.1038/leu.2016.81. [Epub ahead of print]
Leukemia often results in severe anemia, which may significantly contribute to patient mortality and morbidity. However, the mechanisms underlying defective erythropoiesis in leukemia have not been fully elucidated. In this study, we demonstrated that insufficient erythropoiesis in an immunocompeten
PMID 27109512

Detection of RBM15-MKL1 Fusion Was Useful for Diagnosis and Monitoring of Minimal Residual Disease in Infant Acute Megakaryoblastic Leukemia

Takeda Akiko,Shimada Akira,Hamamoto Kazuko,Yoshino Syuuji,Nagai Tomoko,Fujii Yousuke,Yamada Mutsuko,Nakamura Yoshimi,Watanabe Toshiyuki,Watanabe Yuki,Yamamoto Yuko,Sakakibara Kanae,Oda Megumi,Morishima Tsuneo
Acta Medica Okayama 68(2), 119-123, 2014-04
… Acute megakaryocytic leukemia (AMKL) with t(1;22)(p13;q13) is a distinct category of myeloid leukemia by WHO classification and mainly reported in infants and young children. …
NAID 120005425628

中嶋康博,白土基明,中嶋恵理子,油布祐二,藤岡絵里子,松島孝充,髙栁涼一
日本造血細胞移植学会雑誌 2(4), 112-115, 2013
症例は58歳男性。寛解導入不能の急性骨髄性白血病（FAB 分類：M7）に対し，強度減弱前処置を用い同種末梢血幹細胞移植を施行。移植後day 6 に発熱性好中球減少症を合併しドリペネムを投与開始。血液培養よりグラム陽性桿菌が検出され，Bacillus cereus（B. cereus）が疑われたため，バンコマイシンを追加した。Day 8 より，意識レベル低下，左片麻痺が出現，頭部MRI にて髄膜炎像 …
NAID 130003388486

リンク元	「巨核球性白血病」「acute megakaryoblastic leukemia」「巨核球白血病」「骨髄巨核球白血病」
拡張検索	「acute megakaryocytic leukemia」
関連記事	「megakaryocytic」