低分子蛋白尿症
WordNet
- unrefined in character; "low comedy"
- an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow" (同)depression
- a low level or position or degree; "the stock market fell to a new low"
- used of sounds and voices; low in pitch or frequency (同)low-pitched
- very low in volume; "a low murmur"; "the low-toned murmur of the surf" (同)low-toned
- in a low position; near the ground; "the branches hung low"
- less than normal in degree or intensity or amount; "low prices"; "the reservoir is low"
- literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow"
- (statistics) a coefficient assigned to elements of a frequency distribution in order to represent their relative importance (同)weighting
- sports equipment used in calisthenic exercises and weightlifting; it is not attached to anything and is raised and lowered by use of the hands and arms (同)free weight, exercising weight
- an artifact that is heavy
- the vertical force exerted by a mass as a result of gravity
- the relative importance granted to something; "his opinion carries great weight"; "the progression implied an increasing weightiness of the items listed" (同)weightiness
- an oppressive feeling of heavy force; "bowed down by the weight of responsibility"
- have a certain weight
- determine the weight of; "The butcher weighed the chicken" (同)librate
- to be oppressive or burdensome; "weigh heavily on the mind", "Something pressed on his mind" (同)press
- relating to simple or elementary organization; "proceed by more and more detailed analysis to the molecular facts of perception"--G.A. Miller
- relating to or produced by or consisting of molecules; "molecular structure"; "molecular oxygen"; "molecular weight is the sum of all the atoms in a molecule"
- adjusted to reflect value or proportion; "votes weighted according to the size of constituencies"; "a law weighted in favor of landlords"; "a weighted average"
PrepTutorEJDIC
- (高さ・位置が)『低い』,低い所にある / (価格・数量・程度などが)『低い』,少ない / (身分・地位などが)『低い』,卑しい / (人格・行為などが)『卑しい』,下劣な,下品な / 《補語にのみ用いて》(体が)『弱った』;元気のない,憂うつな / (供給が)不十分な;(…が)乏しい《+『in』(『on』)+『名』》 / (音・声が)低い,小さい / (生物が)下等な / 『低く』,低い所に / (価格・程度などが)『安く』,低く / 低い声(調子)で;静かに / 最低点,最低水準
- (牛の)モーという鳴き声 / (牛が)モーと鳴く
- 〈u〉『重さ』,重量,目方;体重;《a weight》(…の)重さ《+of+名》 / 〈u〉重さ(重力が物体に及ぼす力) / 〈u〉衡法(重量を示す体係) / 〈c〉重量単位 / 〈c〉(はかりの)おもり,分銅;(一般に)重いもの,おもし / 〈u〉重要性,価値 / 〈u〉《しばしば a weight》精神的な重荷,負担 / (…で)…‘に'重荷を負わせる;…‘を'圧迫する;苦しめる《+名+with+名》 / …‘を'重くする
- …‘の'『重さを計る』 / 〈ある重さ〉‘を'『計量する』,計る / (…と比較して)…‘を'『検討する』,考慮する〈+名 against+名〉 / 『重さがある』,目方がかかる / (…にとって)『重要である』,(‥に)重要糸される〈+with+名〉
- 分子の,分子による
- 《補語にのみ用いて》(…に)有利な《+toward+名》
UpToDate Contents
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English Journal
- Flow stimulated endocytosis in the proximal tubule.
- Raghavan V1, Weisz OA.
- Current opinion in nephrology and hypertension.Curr Opin Nephrol Hypertens.2015 Jul;24(4):359-65. doi: 10.1097/MNH.0000000000000135.
- PURPOSE OF REVIEW: The proximal tubule plays a critical role in the reabsorption of ions, solutes and low molecular weight proteins from the glomerular filtrate. Although the proximal tubule has long been known to acutely modulate ion reabsorption in response to changes in flow rates of the glomerul
- PMID 26050123
- In-depth phenotyping of a Donnai-Barrow patient helps clarify proximal tubule dysfunction.
- Dachy A1, Paquot F, Debray G, Bovy C, Christensen EI, Collard L, Jouret F.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2015 Jun;30(6):1027-31. doi: 10.1007/s00467-014-3037-7. Epub 2015 Mar 31.
- BACKGROUND: The megalin/cubilin/amnionless complex is essential for albumin and low molecular weight (LMW) protein reabsorption by renal proximal tubules (PT). Mutations of the LRP2 gene encoding megalin cause autosomal recessive Donnai-Barrow/facio-oculo-acoustico-renal syndrome (DB/FOAR), which is
- PMID 25822460
- Variable expression pattern in Donnai-Barrow syndrome: Report of two novel LRP2 mutations and review of the literature.
- Khalifa O1, Al-Sahlawi Z2, Imtiaz F3, Ramzan K3, Allam R3, Al-Mostafa A3, Abdel-Fattah M4, Abuharb G5, Nester M6, Verloes A7, Al-Zaidan H8.
- European journal of medical genetics.Eur J Med Genet.2015 May;58(5):293-9. doi: 10.1016/j.ejmg.2014.12.008. Epub 2015 Feb 13.
- Donnai-Barrow syndrome (DBS; MIM 222448) is characterized by typical craniofacial anomalies (major hypertelorism with bulging eyes), high grade myopia, deafness and low molecular weight proteinuria. The disorder results from mutations in the low density lipoprotein receptor-related protein 2 gene LR
- PMID 25682901
Japanese Journal
- 低年齢でくる病を呈したDent 病の本邦男児の1 例
- 濵平 陽史,稲熊 洋祐,堀之内 智子,五百蔵 智明,久呉 真章,石森 真吾,貝藤 裕史,飯島 一誠
- Nihon Shoni Jinzobyo Gakkai Zasshi 26(2), 297-303, 2014
- Dent 病は低分子蛋白尿,高カルシウム尿症,腎石灰化/腎結石を特徴とし,成人期には腎不全に至る可能性があるX 染色体性遺伝疾患であり,主たる原因はクロライドチャンネル5(ClC-5)遺伝子(CLCN5)の異常による。英国からの報告例ではくる病は多いとされるが,日本ではくる病を呈するものは少ないとされ,報告例も少ない。また治療・管理については確立されたものはない。症例は2 歳4 か月の男児で,兄が …
- NAID 130004495425
- A Case of Juvenile Sjögren's Syndrome with Interstitial Nephritis
- Igarashi Toru,Itoh Yasuhiko,Shimizu Akira,Igarashi Tsutomu,Yoshizaki Kaoru,Fukunaga Yoshitaka
- Journal of Nippon Medical School 79(4), 286-290, 2012
- … Urinalysis showed proteinuria and a β2-microglobulin concentration of 11,265 mg/L. … Thus, this patient had low molecular weight proteinuria. …
- NAID 130004147180
- OCRL1およびCLCN5に遺伝子変異を認めないDent病の兄妹例
- 木全 貴久,蓮井 正史,山下 美代子,金子 一成,野津 寛大,飯島 一誠
- Nihon Shoni Jinzobyo Gakkai Zasshi 24(1), 92-95, 2011
- 13歳と10歳の兄妹で,学校検尿で発見された尿細管性蛋白尿の精査のために紹介受診した。兄妹ともに浮腫や高血圧はなく,成長・発達ともに正常で,難聴や白内障などの腎外症状も見られなかった。血液検査でも異常所見はなく,高カルシウム尿症も認めなかった。 これらの所見からDent病と診断し,病因遺伝子とされているCLCN5とOCRL1を解析したが,いずれにも変異を認めなかった。3年間,兄の尿中β2-ミクロ …
- NAID 130001353984
Related Links
- 1. Am J Kidney Dis. 1996 Jun;27(6):803-8. Low molecular weight proteinuria in human immunodeficiency virus-infected patients. Kabanda A, Vandercam B, Bernard A, Lauwerys R, van Ypersele de Strihou C. Nephrology Unit, Catholic ...
- 1. Kidney Int. 1995 Nov;48(5):1571-6. Low molecular weight proteinuria in Chinese herbs nephropathy. Kabanda A, Jadoul M, Lauwerys R, Bernard A, van Ypersele de Strihou C. Nephrology Unit, Catholic University of Louvain, Medical ...
★リンクテーブル★
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- 英
- low molecular weight proteinuria
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特発性低分子蛋白尿症
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- 関
- deficient、inadequate、insufficiency、insufficient、insufficiently、poorly、scanty
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- 関
- comparative、compare、comparison、weighing
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- 関
- mol、molecularly、molecule、numerator
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- 関
- summation
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- 関
- molecular mass、Mr、Mw