WordNet

the collection and study of postage stamps (同)stamp collecting, stamp_collection
in an immaculate manner; "gone was the casually dressed Canadian she had thought a backwoodsman--this man was immaculately tailored"
in an inarticulate manner; "he talked inarticulately about the accident that had just taken his wifes life"
in grief-stricken loneliness; without comforting circumstances or prospects (同)disconsolately
of a later stage in the development of a language or literature; used especially of dead languages; "Late Greek"
later than usual or than expected; "the train arrived late"; "we awoke late"; "the children came late to school"; "notice came so tardily that we almost missed the deadline"; "I belatedly wished her a happy birthday" (同)belatedly, tardily
at or toward an end or late period or stage of development; "the late phase of feudalism"; "a later symptom of the disease"; "later medical science could have saved the child" (同)later
of the immediate past or just previous to the present time; "a late development"; "their late quarrel"; "his recent trip to Africa"; "in recent months"; "a recent issue of the journal" (同)recent
at an advanced age or stage; "she married late"; "undertook the project late in her career"
being or occurring at an advanced period of time or after a usual or expected time; "late evening"; "late 18th century"; "a late movie"; "took a late flight"; "had a late breakfast"
having died recently; "her late husband"

PrepTutorEJDIC

『近ごろ』,最近
切手収集,切手研究
(定刻・通常・予定の時間より)『遅れた』,遅い / (時刻が)『遅い』,遅く始まる,遅くまで続く;夜更けの / (時期が)『遅い』,終りごろの,後期の / 『最近の』,最新の(recent) / 《the~,one's~》『前の』,先の,前任の(former) / 《the~,one's~》『故』…,つい先ごろ死んだ / (定刻などより)『遅れて』,遅く / (時刻が)『遅く』,遅くまで,(特に)夜更けに;(時期が)遅く,終りごろに / 『最近』,近ごろ(recently)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/10/07 03:45:31」(JST)

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1. 男性不妊症の治療 treatment of male infertility
2. 男性不妊症の原因 causes of male infertility
3. 成人における成長ホルモン欠乏症 growth hormone deficiency in adults
4. 小児単極性うつ病：疫学、臨床的特徴、評価、および診断 pediatric unipolar depression epidemiology clinical features assessment and diagnosis

English Journal

Antinuclear antibody screening by ELISA and IF techniques: discrepant results in juvenile idiopathic arthritis but consistency in childhood systemic lupus erythematous.

Spârchez M1, Delean D, Samaşcă G, Miu N, Spârchez Z.Author information 12nd Department of Pediatrics, The Children's Hospital at Cluj-Napoca, "Iuliu Haţieganu" University of Medicine and Pharmacy, 3-5 Crisan Street, 400177, Cluj-Napoca, Romania, mihaelaspirchez@gmail.com.AbstractLately, many hospital laboratories are using for antinuclear antibody (ANA) screening the solid-phase immunoassays (ELISA-ANA) instead of the traditional immunofluorescence ANA test (IF-ANA). Results of previous studies that compare the two technologies show poor correlation between them in both juvenile idiopathic arthritis (JIA) and childhood lupus erythematous (SLE) patients. In this study, we investigated whether ELISA-ANA and traditional IF-ANA results are comparable in pediatric patients with different rheumatic diseases. A total of 156 consecutive patients were included in the study-90 children with JIA, 33 with reactive arthritis, 19 with SLE, 4 with idiopathic chronic uveitis, and 10 with other systemic rheumatic diseases. ANA determination was performed using both assays. The higher rate of discrepancies between the two methods of ANA screening appeared in the JIA population (19/90, p < 0.001). All JIA patients with false-negative results by ELISA had significant or high IF-ANA titres. The prevalence of JIA-associated uveitis was higher in the group of false-negative ELISA-ANA children than in the ELISA-positive patients but without statistical significance (p = 0.62). On the contrary, in SLE group, the consistency rate of the two assays was 100 %, and the reactivity levels of ELISA-ANA were significantly higher than in ELISA-positive JIA patients (p < 0.001). ELISA seems to be a reliable method for screening ANA in childhood SLE, but not in JIA. Limited by the few SLE patients, our findings need further consideration.
Clinical rheumatology.Clin Rheumatol.2014 Feb 21. [Epub ahead of print]
Lately, many hospital laboratories are using for antinuclear antibody (ANA) screening the solid-phase immunoassays (ELISA-ANA) instead of the traditional immunofluorescence ANA test (IF-ANA). Results of previous studies that compare the two technologies show poor correlation between them in both juv
PMID 24557079

Systems Biology: A New Tool for Farm Animal Science.

Hollung K, Timperio AM, Olivan M, Kemp C, Coto-Montes A, Sierra V, Zolla L1.Author information 1Largo dell'Università snc 01100 Viterbo Italy. zolla@unitus.it.AbstractIt is rapidly emerging that the tender meat phenotype is affected by an enormous amounts of variables, not only tied to genetics (livestock breeding selection), but also to extrinsic factors, such as the feeding conditions, physical activity, rearing environment, administration of hormonal growth promotants, pre-slaughter handling and stress. Proteomics has been widely accepted by meat scientists over the last years and is now commonly used to shed light on the postmortem processes involved in meat tenderization. This review discusses the latest findings with the use of proteomics and systems biology to study the different biochemical pathways postmortem aiming at understanding the concerted action of different molecular mechanisms responsible for meat quality. The conversion of muscle to meat postmortem can be described as a sequence of events involving molecular pathways controlled by a complex interplay of many factors. Among the different pathways emerging are the influence of apoptosis and lately also the role of autophagy in muscle postmortem development. This review want shows as systems-wide integrated investigations (metabolomics, transcriptomics, interactomics, phosphoproteomics, mathematical modeling), which have emerged as complementary tools to proteomics, have helped establishing a few milestones in our understanding of the events leading from muscle to meat conversion.
Current protein & peptide science.Curr Protein Pept Sci.2014 Feb 21. [Epub ahead of print]
It is rapidly emerging that the tender meat phenotype is affected by an enormous amounts of variables, not only tied to genetics (livestock breeding selection), but also to extrinsic factors, such as the feeding conditions, physical activity, rearing environment, administration of hormonal growth pr
PMID 24555891

Selenium Cytotoxicity in Cancer.

Wallenberg M1, Misra S, Björnstedt M.Author information 1Karolinska Institutet, Department of Laboratory Medicine, Division of Pathology F46, Karolinska University Hospital Huddinge, Stockholm, Sweden.AbstractSelenium is an essential trace element with growth modulating properties. Decades of research clearly demonstrate that selenium compounds inhibit the growth of malignant cells in diverse experimental model systems. However, the growth modulating and cytotoxic mechanisms are diverse and far from clear. Lately, a remarkable tumour selective cytotoxicity of selenium compounds has been shown, indicating the potential of selenium in the treatment of cancer. Of particular interest are the redox-active selenium compounds exhibiting cytotoxic potential to tumour cells. These selenium compounds elicit complex patterns of pharmacodynamics and pharmacokinetics, leading to cell death pathways that differ among compounds. Modern oncology often focuses on targeted ligand-based therapeutic strategies that are specific to their molecular targets. These drugs are initially efficient but the tumour cells often rapidly develop resistance against these drugs. In contrast, certain redox-active selenium compounds induce complex cascades of pro-death signalling at pharmacological concentrations with superior tumour specificity. The target molecules are often the ones that are important for the survival of cancer cells and often implicated in drug resistance. Therefore, the chemotherapeutic applications of selenium offer great possibilities of multi-target attacks on tumour cells. This MiniReview focuses on the tumour-specific cytotoxic effects of selenium, with special emphasis on cascades of cellular events induced by the major groups of pharmacologically active selenium compounds. Furthermore, the great pharmacological potential of selenium in the treatment of resistant cancers is discussed. This article is protected by copyright. All rights reserved.
Basic & clinical pharmacology & toxicology.Basic Clin Pharmacol Toxicol.2014 Feb 17. doi: 10.1111/bcpt.12207. [Epub ahead of print]
Selenium is an essential trace element with growth modulating properties. Decades of research clearly demonstrate that selenium compounds inhibit the growth of malignant cells in diverse experimental model systems. However, the growth modulating and cytotoxic mechanisms are diverse and far from clea
PMID 24529300

Japanese Journal

情報学

Journal of informetrics 10(4), 981-1004, 2016-11
NAID 120005853310

Polyoxazoline multivalently conjugated with indocyanine green for sensitive in vivo photoacoustic imaging of tumors

Scientific Reports 6, 2016-09-26
NAID 120005850222

おもてなしサービスのプロセスデザインにおける課題

専修大学情報科学研究所所報 87, 1-8, 2016-07-25
NAID 120005848818

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