WordNet
- the act of positioning close together (or side by side); "it is the result of the juxtaposition of contrasting colors" (同)apposition, collocation
- a side-by-side position
- very close in space or time; "proximate words"; "proximate houses"
- closest in degree or order (space or time) especially in a chain of causes and effects; "news of his proximate arrival"; "interest in proximate rather than ultimate goals"
- situated nearest to point of attachment or origin; "the proximal end of a bone"
PrepTutorEJDIC
- 並置,並列
- (時間・順序・血族などが)最も近い,直接の;(…の)直前(直後)の《+『to』+『名』》
- (骨などが)近位の(体の中心に近いこと)
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/07/23 07:05:52」(JST)
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- 1. 非ホジキンリンパ腫の病理の概要 overview of the pathobiology of the non hodgkin lymphomas
- 2. HIV感染およびAIDSの神経精神学的側面の概要 overview of the neuropsychiatric aspects of hiv infection and aids
- 3. 血液悪性腫瘍における細胞遺伝子解析の一般的側面 general aspects of cytogenetic analysis in hematologic malignancies
- 4. 多発性骨髄腫の病理生物学 pathobiology of multiple myeloma
- 5. 早期興奮症候群における副伝導路の解剖学、病態生理、および局在 anatomy pathophysiology and localization of accessory pathways in the preexcitation syndrome
English Journal
- Probing the surface speciation of uranium (VI) on iron (hydr)oxides by in situ ATR FT-IR spectroscopy.
- Foerstendorf H1, Jordan N2, Heim K2.Author information 1Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf e.V., Bautzner Landstr. 400, D-01328 Dresden, Germany. Electronic address: foersten@hzdr.de.2Institute of Resource Ecology, Helmholtz-Zentrum Dresden-Rossendorf e.V., Bautzner Landstr. 400, D-01328 Dresden, Germany.AbstractThe surface speciation of uranium(VI) on maghemite (γ-Fe2O3) was elucidated at the spectroscopic level for the first time. By means of in situ ATR FT-IR measurements, the formation of uranium(VI) outer-sphere complexes was revealed under anoxic conditions and in ambient atmosphere at mildly acid conditions. This type of complexation was verified by the frequency of the ν3(UO2) mode observed for the surface species, the impact of the ionic strength of the background electrolyte on U(VI) sorption and by the high reversibility of the sorption process monitored by on line spectroscopy. The impact of carbonate ions from atmospherically derived CO2 on U(VI) sorption on maghemite was investigated. Although the surface speciation of the carbonate ions presumably change from a monodentate coordination on maghemite to a bidentate coordination in the ternary sorption system, the U(VI) speciation is not changed. A contrasting juxtaposition of comparable results obtained from maghemite and ferrihydrite reveals a basically different type of U(VI) complexation, namely outer and inner spheric coordination.
- Journal of colloid and interface science.J Colloid Interface Sci.2014 Feb 15;416:133-8. doi: 10.1016/j.jcis.2013.10.054. Epub 2013 Nov 8.
- The surface speciation of uranium(VI) on maghemite (γ-Fe2O3) was elucidated at the spectroscopic level for the first time. By means of in situ ATR FT-IR measurements, the formation of uranium(VI) outer-sphere complexes was revealed under anoxic conditions and in ambient atmosphere at mildly acid co
- PMID 24370412
- Protein-mediated chromosome pairing of repetitive arrays.
- Mirkin EV1, Chang FS1, Kleckner N2.Author information 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.2Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: kleckner@fas.harvard.edu.AbstractChromosomally integrated arrays of lacO and tetO operator sites visualized by LacI and TetR repressor proteins fused with GFP (green fluorescent protein) (or other fluorescent proteins) are widely used to monitor the behavior of chromosomal loci in various systems. However, insertion of such arrays and expression of the corresponding proteins is known to perturb genomic architecture. In several cases, juxtaposition of such arrays located on different chromosomes has been inferred to reflect pairing of the corresponding loci. Here, we report that a version of TetR-GFP mutated to disrupt GFP dimerization (TetR-A206KGFP or "TetR-kGFP") abolishes pairing of tetO arrays in vivo and brings spatial proximity of chromosomal loci marked with those arrays back to the wild-type level. These data argue that pairing of arrays is caused by GFP dimerization and thus presents an example of protein-assisted interaction in chromosomes. Arrays marked with another protein, TetR-tdTomato, which has a propensity to form intramolecular dimers instead of intermolecular dimers, also display reduced level of pairing, supporting this idea. TetR-kGFP provides an improved system for studying chromosomal loci with a low pairing background.
- Journal of molecular biology.J Mol Biol.2014 Feb 6;426(3):550-7. doi: 10.1016/j.jmb.2013.11.001. Epub 2013 Nov 8.
- Chromosomally integrated arrays of lacO and tetO operator sites visualized by LacI and TetR repressor proteins fused with GFP (green fluorescent protein) (or other fluorescent proteins) are widely used to monitor the behavior of chromosomal loci in various systems. However, insertion of such arrays
- PMID 24211468
- CHD5 is required for spermiogenesis and chromatin condensation.
- Zhuang T1, Hess RA2, Kolla V1, Higashi M1, Raabe TD3, Brodeur GM4.Author information 1Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.2Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, United States.3Penn Gene Targeting Service, University of Pennsylvania, Philadelphia, PA 19104, United States.4Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States; The Department of Pediatrics, Perelman School of Medicine, Philadelphia, PA 19104, United States. Electronic address: Brodeur@email.chop.edu.AbstractHaploid spermatids undergo extensive cellular, molecular and morphological changes to form spermatozoa during spermiogenesis. Abnormalities in these steps can lead to serious male fertility problems, from oligospermia to complete azoospermia. CHD5 is a chromatin-remodeling nuclear protein expressed almost exclusively in the brain and testis. Male Chd5 knockout (KO) mice have deregulated spermatogenesis, characterized by immature sloughing of spermatids, spermiation failure, disorganization of the spermatogenic cycle and abnormal head morphology in elongating spermatids. This results in the inappropriate placement and juxtaposition of germ cell types within the epithelium. Sperm that did enter the epididymis displayed irregular shaped sperm heads, and retained cytoplasmic components. These sperm also stained positively for acidic aniline, indicating improper removal of histones and lack of proper chromatin condensation. Electron microscopy showed that spermatids in the seminiferous tubules of Chd5 KO mice have extensive nuclear deformation, with irregular shaped heads of elongated spermatids, and lack the progression of chromatin condensation in an anterior-to-posterior direction. However, the mRNA expression levels of other important genes controlling spermatogenesis were not affected. Chd5 KO mice also showed decreased H4 hyperacetylation beginning at stage IX, step 9, which is vital for the histone-transition protein replacement in spermiogenesis. Our data indicate that CHD5 is required for normal spermiogenesis, especially for spermatid chromatin condensation.
- Mechanisms of development.Mech Dev.2014 Feb;131:35-46. doi: 10.1016/j.mod.2013.10.005. Epub 2013 Nov 16.
- Haploid spermatids undergo extensive cellular, molecular and morphological changes to form spermatozoa during spermiogenesis. Abnormalities in these steps can lead to serious male fertility problems, from oligospermia to complete azoospermia. CHD5 is a chromatin-remodeling nuclear protein expressed
- PMID 24252660
- Thermal stability of DNA quadruplex-duplex hybrids.
- Lim KW, Khong ZJ, Phan AT.Author information School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore 637371.AbstractDNA has the capacity to adopt several distinct structural forms, such as duplex and quadruplex helices, which have been implicated in cellular processes and shown to exhibit important functional properties. Quadruplex-duplex hybrids, generated from the juxtaposition of these two structural elements, could find applications in therapeutics and nanotechnology. Here we used NMR and CD spectroscopy to investigate the thermal stability of two classes of quadruplex-duplex hybrids comprising fundamentally distinct modes of duplex and quadruplex connectivity: Construct I involves the coaxial orientation of the duplex and quadruplex helices with continual base stacking across the two components; Construct II involves the orthogonal orientation of the duplex and quadruplex helices with no base stacking between the two components. We have found that for both constructs, the stability of the quadruplex generally increases with the length of the stem-loop incorporated, with respect to quadruplexes comprising nonstructured loops of the same length, which showed a continuous drop in stability with increasing loop length. The stability of these complexes, particularly Construct I, can be substantially influenced by the base-pair steps proximal to the quadruplex-duplex junction. Bulges at the junction are largely detrimental to the adoption of the desired G-quadruplex topology for Construct I but not for Construct II. These findings should facilitate future design and prediction of quadruplex-duplex hybrids.
- Biochemistry.Biochemistry.2014 Jan 14;53(1):247-57. doi: 10.1021/bi401161a. Epub 2013 Dec 24.
- DNA has the capacity to adopt several distinct structural forms, such as duplex and quadruplex helices, which have been implicated in cellular processes and shown to exhibit important functional properties. Quadruplex-duplex hybrids, generated from the juxtaposition of these two structural elements,
- PMID 24367892
Japanese Journal
- ロンドン国際シュルレアリスム展(一九三六年)にみる相隔たるもの同士の並置をめぐる諸問題
- 石井 祐子
- 美學 64(1), 143-154, 2013-06-30
- … Its method was "the juxtaposition of mutually distant objects" which was related to the idea of collage cultivated in surrealism especially in 1930's. …
- NAID 110009624871
- English and Discourses of Identity in Japan
- Rudolph Nathanael
- 武庫川女子大学紀要. 人文・社会科学編 60, 51-62, 2013
- … From thetime of the Meiji period, social, economic, political and educational discourses in Japanese society haveserved to construct a" Japan" and notion of" Japaneseness" that focuses on a juxtaposition of Japan and theWest. …
- NAID 110009575098
- 後期中英語における「知っている」および「できる」を表す動詞についての覚え書
- 松瀬 憲司,マツセ ケンジ,Matsuse Kenji
- 熊本大学教育学部紀要. 人文科学 61, 47-57, 2012-12-12
- … In addition, the frequent juxtaposition of may and can in the same sentence structure also must have contributed to reinforce the shift. …
- NAID 110009517205
- 超高圧変成帯中のザクロ石橄欖岩およびエクロジャイトの温度圧力履歴解析法 : 地質温度圧力計の概説と適用
- 苗村 康輔,中村 大輔,平島 崇男
- 岩石鉱物科学 41(6), 225-246, 2012-11-30
- … Therefore, elucidation of juxtaposition processes between the mantle material and the host crustal material is one of main subjects for the petrology in the UHP belts. … Delineating of pressure-temperature (P-T) paths of these UHP garnet peridotite bodies can give us indispensable constraints to clarify the juxtaposition process of mantle and crustal materials in the continent-collision settings and the exhumation processes of deeply subducted rocks with higher density than the crustal rocks. …
- NAID 10031134512
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★リンクテーブル★
| リンク元 | 「proximate」「proximal」「proximally」「proximal portion」 |
「proximate」
- v.
- 近位の、近接する
「proximal」
- adj.
- 近位の、基部の
「proximally」
- 近位に