adj.

低悪性度の, 緩徐進行型の

関: agressive

WordNet

(of tumors, e.g.) slow to heal or develop and usually painless; "an indolent ulcer"; "leprosy is an indolent infectious disease"
taking on different forms; "eyes...of that baffling protean grey which is never twice the same"
of inferior quality
in an indolent manner; "he lives indolently with his relatives"

PrepTutorEJDIC

無精な,怠惰な
(ギリシア神話の海神Proteusのように)変幻自在な

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/09/08 20:30:30」(JST)

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1. 尿毒症毒素 uremic toxins
2. 慢性腎疾患における甲状腺機能 thyroid function in chronic kidney disease
3. 腸内ガスと膨満 intestinal gas and bloating
4. セフェム系 cephalosporins
5. 肺炎桿菌感染症の微生物学および病因 microbiology and pathogenesis of klebsiella pneumoniae infection

English Journal

Characterizing the metabolic heterogeneity in human breast cancer xenografts by 3D high resolution fluorescence imaging.

Xu HN, Zheng G, Tchou J, Nioka S, Li LZ.SourceMolecular Imaging Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, USA ; Britton Chance Laboratory of Redox Imaging, Johnson Research Foundation, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, USA.
SpringerPlus.Springerplus.2013 Dec;2(1):73. Epub 2013 Feb 28.
We previously reported that tumor mitochondrial redox state and its heterogeneity distinguished between the aggressive and the indolent breast cancer xenografts, suggesting novel metabolic indices as biomarkers for predicting tumor metastatic potential. Additionally, we reported that the identified
PMID 23543813

Curcumin inhibits invasion and metastasis in K1 papillary thyroid cancer cells.

Zhang CY, Zhang L, Yu HX, Bao JD, Sun Z, Lu RR.SourceKey Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, 20 Qian Rong Road, Wuxi, Jiangsu 214063, China; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu 214122, China.
Food chemistry.Food Chem.2013 Aug 15;139(1-4):1021-8. doi: 10.1016/j.foodchem.2013.02.016. Epub 2013 Feb 16.
Curcumin, the active constituent of dietary spice turmeric, possesses a strong potential for cancer prevention and treatment. However, there is no study to address the effects of curcumin on invasion and metastasis of thyroid cancers. Thyroid cancer is the most common malignancy of endocrine organs,
PMID 23561205

Indolent T-Lymphoblastic Proliferation (iT-LBP): A Review of Clinical and Pathologic Features and Distinction from Malignant T-Lymphoblastic Lymphoma.

Ohgami RS, Arber DA, Zehnder JL, Natkunam Y, Warnke RA.SourceDepartment of Pathology, Stanford University Medical Center, Stanford, CA 94305.
Advances in anatomic pathology.Adv Anat Pathol.2013 May;20(3):137-40. doi: 10.1097/PAP.0b013e31828d17ec.
In recent years, a new pathologic entity has emerged: indolent T-lymphoblastic proliferation (iT-LBP). iT-LBPs share immunophenotypic similarities with T-lymphoblastic lymphoma; however, T-lymphoblastic proliferations are clinically indolent, and unlike the malignant counterpart, these expansions of
PMID 23574769

Thalidomide in systemic mastocytosis: results from an open-label, multicentre, phase II study.

Gruson B, Lortholary O, Canioni D, Chandesris O, Lanternier F, Bruneau J, Grosbois B, Livideanu C, Larroche C, Durieu I, Barete S, Sevestre H, Diouf M, Chaby G, Marolleau JP, Dubreuil P, Hermine O, Damaj G.SourceDépartement d'Hématologie, Centre Hospitalier Universitaire (CHU) d'Amiens, Amiens, France.
British journal of haematology.Br J Haematol.2013 May;161(3):434-42. doi: 10.1111/bjh.12265. Epub 2013 Feb 22.
Mastocytosis can lead to organ failure as well as systemic symptoms that can be disabling, with considerable deterioration in quality of life. Beside symptomatic treatments, interferon-α and purine analogues have been shown to be effective but complete or long-term remission is rarely obtained with
PMID 23432617

Japanese Journal

濾胞性リンパ腫に対するリツキシマブ併用化学療法の当科における成績

風間啓至/寺村正尚/榎本有希/渡邉彩/石森紀子/丁曄/志村華絵/兒玉聖子/田中紀奈/三橋健次郎/石山みどり/吉永健太郎/今井陽一/志関雅幸/森直樹/泉二登志子
東京女子医科大学雑誌 83(E2), E563-E568, 2013-03-31
濾胞性リンパ腫は低悪性度B細胞リンパ腫として位置づけられる疾患である. 抗CD20抗体であるリツキシマブを併用した化学療法により予後は改善されたが,依然治癒が困難なリンパ腫である. 2002年1月から2012年6月までの当科でリツキシマブ併用化学療法が施行された濾胞性リンパ腫61例について後ろ向き解析を行った.年齢中央値は61才(41-85才). WHO分類によるGrade 1/2は44例で, G …
NAID 110009575066

肺転移巣切除後, 長期生存が得られた alveolar soft part sarcoma の1例

三浦奈央子,伊藤謙作,濱田千鶴,梶原浩太郎,横山秀樹,大城由美
日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 26(5), 533-535, 2012-07-15
Alveolar soft part sarcoma（ASPS）は若年者に好発する稀な腫瘍である．転移を伴わない症例は5年生存率88％と予後良好であるが，遠隔転移を伴う症例は5年生存率20％と予後不良である．今回，我々は，肺転移巣切除後に21年間無再発で経過している症例を経験したので，報告する．症例は30歳代女性．12歳時に左側腹部の手拳大の腫瘍に対して腫瘍摘出術を施行し，ASPSと診断された．術 …
NAID 10030500969

未治療低悪性度B細胞リンパ腫に対するR-CHOP療法におけるdose-dense strategyの有用性に関する第？/？相試験 : JCOG0203の意義 (特集低悪性度B細胞リンパ腫の研究と診療 : Update in 2012)

渡辺隆
血液内科 65(1), 72-82, 2012-07-00
NAID 40019402897

低悪性度B細胞リンパ腫に対するR-CHOP療法の有効性を如何に改善するか?

飛内賢正
臨床血液 53(6), 609-617, 2012-06-30
NAID 10030831553

Related Pictures

★リンクテーブル★

リンク元	「KAP STEP2CK2008 002」「protean」「低悪性度」「low-grade」「緩徐進行型」
拡張検索	「indolent systemic mastocytosis」

「KAP STEP2CK2008 002」

　　[★]

glossary

lancinating
throbbing
hilar lymphadenopathy
vitiligo
alopecia areata 円形脱毛症
trichotillomania
psyllium おおばこかオオバコ。緩下薬らしい
Coxsackie virus 手足口病
indolent 無痛性
commensals 共生
actinomycetes 放線菌

サルコイドーシス

疫学

peak age group for sarcoidosis is 20-40
more common in blacks
African Americanがヒント

病態

lungs, heart, kidneys, skin, liver, or other organ

uveitisも来す？
冒されやすい部位は皮膚、眼、肺

亜急性甲状腺炎

病原体：ウイルス

橋本病

Many patients also have other autoimmune diseases.
ホルモンの変化：hypothyroidism are also present in longer-standing cases. Early in the disease, as in this case, T4 and TSH levels may be normal.
MPO抗体は橋本病に特異的ではない；Graves disease and silent lymphocytic thyroiditisでも上がる

円形脱毛症

円形脱毛症と他の疾患の関連：autoimmune disorders, such as Hashimoto thyroiditis, pernicious anemia, and Addison disease
皮膚科的特徴：exclamation hair

http://www.aafp.org/afp/2003/0701/p93.html

治療：triamcinolone or application of anthralin ointment has been beneficial in hastening recovery

プロペシア

フィナステリドは、5α-還元酵素II型を選択的に抑制することによりテストステロンからジヒドロテストステロンへの変換を阻害し、発毛作用を示すものと考えられる。

http://www.info.pmda.go.jp/go/pack/249900XF1021_2_01/249900XF1021_2_01?view=body

同名半盲

bilateral temporal hemianopia and is due to chiasmatic lesions that compromise the crossing fibers originating from the temporal retina

単純ヘルペスウイルスの初感染患者について

Gingivostomatitis and pharyngitis are the most frequent clinical manifestations of primary herpes simplex virus 1 infection, and are most commonly seen in children and young adults. Clinical signs and symptoms include fever, malaise, myalgias, and cervical adenopathy. Common lesions may involve the hard and soft palate, gingiva, tongue, lips, and facial area.