WordNet

marked by suitability or rightness or appropriateness; "proper medical treatment"; "proper manners"
appropriate for a condition or purpose or occasion or a persons character, needs; "everything in its proper place"; "the right man for the job"; "she is not suitable for the position" (同)right
having all the qualities typical of the thing specified; "wanted a proper dinner; not just a snack"; "he finally has a proper job"
limited to the thing specified; "the city proper"; "his claim is connected with the deed proper"
a support placed beneath or against something to keep it from shaking or falling
a complex neural structure (shaped like a sea horse) consisting of grey matter and located on the floor of each lateral ventricle; intimately involved in motivation and emotion as part of the limbic system; has a central role in the formation of memories
seahorses (同)genus Hippocampus

PrepTutorEJDIC

(目的に)『適切な』,ふさわしい / 《文》《補語にのみ用いて》《『be proper to』+『名』…に固有の,本来備わっている》 / 基準にかなった,正式の / (行き過ぎるぐらいに)礼儀正しい / 《名詞の前にのみ用いて》厳密な,正確な / 《名詞の後に置いて》厳密な意味での,真の,純粋の / 《名詞の前にのみ用いて》すばらしい,すてきな;《おもに英話》全くの
全く,すっかり
支柱,支え / 支えとなる人(物) / …‘を'支える / (…に)…‘を'寄りかからせる《+『名』+『against』+『名』》
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Simvastatin enhances the hippocampal klotho in a rat model of streptozotocin-induced cognitive decline.

Adeli S1, Zahmatkesh M2, Tavoosidana G3, Karimian M4, Hassanzadeh G5.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2017 Jan 4;72:87-94. doi: 10.1016/j.pnpbp.2016.09.009. Epub 2016 Sep 28.
Brain oxidative status is a crucial factor in the development of sporadic Alzheimer's disease (AD). Klotho, an anti-aging protein, diminishes oxidative stress by the induction of manganese superoxide dismutase (MnSOD). Thus, the substances that increase klotho expression could be considered as a pot
PMID 27687042

The level of the zinc homeostasis regulating proteins in the brain of rats subjected to olfactory bulbectomy model of depression.

Rafalo A1, Zadrozna M2, Nowak B2, Kotarska K3, Wiatrowska K3, Pochwat B3, Sowa-Kucma M3, Misztak P4, Nowak G4, Szewczyk B5.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2017 Jan 4;72:36-48. doi: 10.1016/j.pnpbp.2016.08.009. Epub 2016 Aug 24.
BACKGROUND: Zinc transporters (ZnTs) and metallothioneins (MT) are important in maintaining Zn homeostasis in the brain. The present study was designed to find out whether alterations in ZnTs and MTs are associated with the pathophysiology of depression and the mechanism of antidepressant action.MET
PMID 27565434

小山隆太
薬学雑誌. 乙号 134(11), 1171-1177, 2014
… Well-refined wiring of neural circuits is fundamental to proper brain function. … The dentate gyrus has been suggested to serve as a gate that prevents the propagation of epileptiform activity from the entorhinal cortex to the hippocampus. …
NAID 130004712977

Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents

篠原良章,細谷亜季,矢作和子,FRECSKÓ Alex S.,矢口邦雄,Attila Sík,ITAKURA Makoto,TAKAHASHI Masami,平瀬肇
European Journal of Neuroscience 35(5), 702-710, 2012-03
… Fifteen to twenty per cent of the hippocampus proper cells that give rise to CA1 stratum oriens innervation were CA2 pyramidal cells, whereas CA2 cells were a mere 3% for CA1 stratum radiatum innervation. …
NAID 120003959539