WordNet

type genus of the family Cancridae (同)genus Cancer
the fourth sign of the zodiac; the sun is in this sign from about June 21 to July 22 (同)Cancer the Crab, Crab
(astrology) a person who is born while the sun is in Cancer (同)Crab
a small zodiacal constellation in the northern hemisphere; between Leo and Gemini
any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream (同)malignant neoplastic disease
of or relating to the medulla of any body part
containing or consisting of or resembling bone marrow
of or relating to the medulla oblongata
suggestive of a thyroid disorder; "thyroid personality"
of or relating to the thyroid gland; "thyroid deficiency"; "thyroidal uptake" (同)thyroidal
the inner part of an organ or structure in plant or animal

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1. 甲状腺髄様癌：治療および予後 medullary thyroid cancer treatment and prognosis
2. 甲状腺髄様癌：化学療法および免疫療法 medullary thyroid cancer chemotherapy and immunotherapy
3. 甲状腺髄様癌：臨床症状、診断、および病期分類 medullary thyroid cancer clinical manifestations diagnosis and staging
4. 多発性内分泌腫瘍2型の治療のアプローチ approach to therapy in multiple endocrine neoplasia type 2
5. 多発性内分泌腫瘍2型の臨床症状および診断 clinical manifestations and diagnosis of multiple endocrine neoplasia type 2

Lassalle S1,2,3,4,5, Zangari J2,3,4, Popa A3,5,6, Ilie M1,2,3,4,5, Hofman V1,2,3,4,5, Long E1,2,3,4,5, Patey M7, Tissier F8, Belléannée G9, Trouette H9, Catargi B10, Peyrottes I5,11, Sadoul JL12, Bordone O4,5, Bonnetaud C4,5, Butori C1,5, Bozec A2,3,5,13, Guevara N5,13, Santini J5,13, Hénaoui IS3,6, Lemaire G14, Blank O14, Vielh P15, Barbry P3,5,6, Mari B3,5,6, Brest P2,3,5, Hofman P1,2,3,4,5.
Oncotarget.Oncotarget.2016 Mar 29. doi: 10.18632/oncotarget.8458. [Epub ahead of print]
In this study, we performed microRNA (miRNA) expression profiling on a large series of sporadic and hereditary forms of medullary thyroid carcinomas (MTC). More than 60 miRNAs were significantly deregulated in tumor vs adjacent non-tumor tissues, partially overlapping with results of previous studie
PMID 27036030

Germline ESR2 mutation predisposes to medullary thyroid carcinoma and causes up-regulation of RET expression.

Smith J1, Read ML2, Hoffman J3, Brown R4, Bradshaw B5, Campbell C6, Cole T3, Navas JD7, Eatock F8, Gundara JS9, Lian E10, Mcmullan D5, Morgan NV1, Mulligan L10, Morrison PJ11, Robledo M12, Simpson MA13, Smith VE2, Stewart S3, Trembath RC14, Sidhu S9, Togneri FS5, Wake NC1, Wallis Y5, Watkinson JC4, Maher ER15, McCabe CJ2, Woodward ER16.
Human molecular genetics.Hum Mol Genet.2016 Mar 3. pii: ddw057. [Epub ahead of print]
Familial medullary thyroid cancer (MTC) and its precursor, C cell hyperplasia (CCH), is associated with germline RET mutations causing multiple endocrine neoplasia type 2. However, some rare families with apparent MTC/CCH predisposition do not have a detectable RET mutation. To identify novel MTC/CC
PMID 26945007

Sorafenib for the Treatment of Progressive Metastatic Medullary Thyroid Cancer: Efficacy and Safety Analysis.

de Castroneves LA1, Negrão MV2, de Freitas RM3, Papadia C1, Lima JV Jr4, Fukushima JT5, Simão EF6, Kulcsar MA7, Tavares MR8, Jorge AA9, de Castro G Jr2, Hoff PM2, Hoff AO1.
Thyroid : official journal of the American Thyroid Association.Thyroid.2016 Mar;26(3):414-9. doi: 10.1089/thy.2015.0334. Epub 2016 Feb 9.
BACKGROUND: Treatment of advanced medullary thyroid carcinoma (MTC) was recently improved with the approval of vandetanib and cabozantinib. However, there is still a need to explore sequential therapy with more than one tyrosine kinase inhibitor (TKI) and to explore alternative therapies when vandet
PMID 26701095

当科における甲状腺髄様癌の経験―術前血清カルシトニン／ＣＥＡ比は髄様癌の予後予測に有用である―:―術前血清カルシトニン/CEA比は髄様癌の予後予測に有用である―

杉谷巌,鎌田信悦
頭頸部癌 30(4), 583-588, 2004
甲状腺髄様癌では血清calcitonin, CEA値が腫瘍マーカーとして有用であり, calcitonin分泌に比べCEA分泌が優位のものは予後不良であるといわれている。髄様癌におけるcalcitonin/CEA比の予後因子としての有用性について検討した。当科にて経験した髄様癌初取扱い20例 (1986～2004年, 散発性13例, 家族性3家系7例) の5年無再発生存率は80% (再発5例 ; …
NAID 130004509819