同: HNF-4

WordNet

be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
of or relating to or constituting the nucleus of an atom; "nuclear physics"; "nuclear fission"; "nuclear forces"
(weapons) deriving destructive energy from the release of atomic energy; "nuclear war"; "nuclear weapons"; "atomic bombs" (同)atomic
constituting or like a nucleus; "annexation of the suburban fringe by the nuclear metropolis"; "the nuclear core of the congregation"
of or relating to or constituting the nucleus of a cell; "nuclear membrane"; "nuclear division"
pertaining to or affecting the liver; "hepatic ducts"; "hepatic cirrhosis"

PrepTutorEJDIC

(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
『核の』,細胞核の / [『原子』]『核の』
肝臓の;肝臓にきく,肝臓のような色の

UpToDate Contents

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1. 肝線維症の病因 pathogenesis of hepatic fibrosis
2. 肝線維症の新しい治療法 emerging therapies for hepatic fibrosis
3. 肝切除の概要 overview of hepatic resection
4. 肝線維症の非侵襲的評価に用いられる検査 tests used for the noninvasive assessment of hepatic fibrosis
5. 赤血球産生調節 regulation of erythropoiesis

English Journal

Involvement of the nuclear high mobility group B1 peptides released from injured hepatocytes in murine hepatic fibrogenesis.

Kao YH1, Lin YC2, Tsai MS2, Sun CK3, Yuan SS4, Chang CY5, Jawan B6, Lee PH7.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Sep;1842(9):1720-32. doi: 10.1016/j.bbadis.2014.06.017. Epub 2014 Jun 23.
This study investigated the pro-fibrogenic role of high mobility group box 1 (HMGB1) peptides in liver fibrogenesis. An animal model of carbon tetrachloride (CCl4)-induced liver fibrosis was used to examine the serum HMGB1 levels and its intrahepatic distribution. The increased serum HMGB1 levels we
PMID 24970745

Dynamic and Coordinated Regulation of KEAP1-NRF2-ARE and p53/p21 Signaling Pathways Is Associated with Acetaminophen Injury Responsive Liver Regeneration.

Fan X1, Chen P1, Tan H1, Zeng H1, Jiang Y1, Wang Y1, Wang Y1, Hou X1, Bi H2, Huang M2.
Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2014 Sep;42(9):1532-9. doi: 10.1124/dmd.114.059394. Epub 2014 Jul 7.
Acetaminophen (APAP) overdose is the leading cause of drug-induced liver injury. Compensatory liver regeneration is crucial for the final outcome of toxicant-induced injury. However, the molecular mechanisms underlying compensatory liver regeneration in mice after APAP-induced liver injury are not c
PMID 25002747

Med25 is required for estrogen receptor alpha (ERα)-mediated regulation of human CYP2C9 expression.

Shi Z1, Yang W2, Goldstein JA3, Zhang SY4.
Biochemical pharmacology.Biochem Pharmacol.2014 Aug 15;90(4):425-31. doi: 10.1016/j.bcp.2014.06.016. Epub 2014 Jun 21.
The CYP2C subfamily of cytochrome P450 enzymes is an important class of drug metabolizing enzymes in human liver. CYP2C9 is the most abundant member of the human CYP2C subfamily in liver and metabolizes ∼15% of the therapeutic drugs as well as other xenobiotics and endogenous compounds. A number o
PMID 24960263

Japanese Journal

Protective Effect of Genistein on Lipopolysaccharide/D-Galactosamine-Induced Hepatic Failure in Mice

Lin Xing,Zhang Shijun,Huang Renbin,Wei Ling,Liang Chunhong,Chen Yongxing,Lv Shujuan,Liang Shuang,Wu Xiaoyan,Huang Quanfang
Biological and Pharmaceutical Bulletin 37(4), 625-632, 2014
… This study examined the effect of genistein from Hydrocotyle sibthorpioides on lipopolysaccharide (LPS)/<span style="font-variant: small-caps;">D</span>-galactosamine (<span style="font-variant: small-caps;">D</span>-GalN)-induced acute hepatic failure. …
NAID 130003390981

Asiatic Acid from Potentilla chinensis Attenuate Ethanol-Induced Hepatic Injury via Suppression of Oxidative Stress and Kupffer Cell Activation

Wei Jinbin,Huang Quanfang,Huang Renbin [他],Chen Yongxing,Lv Shujuan,Wei Ling,Liang Chunhong,Liang Shuang,Zhuo Lang,Lin Xing
Biological and Pharmaceutical Bulletin 36(12), 1980-1989, 2013
… This study examined the effect of Asiatic acid from Potentilla chinensis (AAPC) on chronic ethanol-induced hepatic injury. …
NAID 130003382073

症例報告異常門脈域を内包し,限局性結節性過形成類似病変との鑑別が問題となったhepatocyte nuclear factor 1α-不活化型肝細胞腺腫の1例

伊藤勝彦,近藤福雄,大多和哲 [他],石井隆之,清水善明,小川清,岸宏久,小豆畑康児,宮崎勝
肝臓 54(2), 135-142, 2013
… A 26-year man visited a nearby clinic because of epigastralgia and a large hepatic mass. … On the abdominal CT scan, the hepatic large mass was found in the S4 segment. … The hepatic large mass was completely encapsulated with a clear boundary and hematoma existed in the central portion of the mass. …
NAID 130003368662