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a sweet syrupy trihydroxy alcohol obtained by saponification of fats and oils (同)glycerin, glycerine

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1. 上顆炎（テニス肘およびゴルフ肘） epicondylitis tennis and golf elbow
2. 小児における細菌性髄膜炎：神経学的合併症を予防するデキサメタゾンおよびその他の対策 bacterial meningitis in children dexamethasone and other measures to prevent neurologic complications
3. 腹膜透析液 peritoneal dialysis solutions
4. 食道運動障害：臨床症状、診断およびマネージメント esophageal motility disorders clinical manifestations diagnosis and management
5. 遺伝性球状赤血球症：臨床的特徴、診断および治療 hereditary spherocytosis clinical features diagnosis and treatment

Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis.

Sugiura T, Dohi Y, Yamashita S, Ohte N, Ito S, Iwaki S, Hirowatari Y, Ohkawa R, Mishima Y, Yatomi Y, Kimura G, Fujii S.SourceDepartment of Cardio-Renal Medicine and Hypertension, Nagoya City University Graduate School of Medical Sciences, Tokyo, Japan. tomosugi@med.nagoya-cu.ac.jp
Coronary artery disease.Coron Artery Dis.2012 Jun;23(4):234-8.
OBJECTIVES: Serotonin stored in platelets is released into plasma on aggregation and activation in atherosclerotic diseases. Sphingosine 1-phosphate (S1P) in plasma is mainly derived from red blood cells and is responsible for the production of nitric oxide in endothelial cells and protects vasculat
PMID 22356865

In vitro suppression of drug-induced methaemoglobin formation by Intralipid(®) in whole human blood: observations relevant to the 'lipid sink theory'.

Samuels TL, Willers JW, Uncles DR, Monteiro R, Halloran C, Dai H.SourceDepartment of Anaesthesia, Worthing Hospital, Worthing, UK. dr.tsamuels@gmail.com
Anaesthesia.Anaesthesia.2012 Jan;67(1):23-32. doi: 10.1111/j.1365-2044.2011.06914.x. Epub 2011 Oct 17.
To provide further evidence for the lipid sink theory, we have developed an in vitro model to assess the effect of Intralipid® 20% on methaemoglobin formation by drugs of varying lipid solubility. Progressively increasing Intralipid concentrations from 4 to 24 mg.ml⁻¹ suppressed methaemoglobin
PMID 21999405

瑞慶覧努,佐藤成,後藤均,橋本宗敬,赤松大二朗,菅原宏文,清水拓也,三浦禎司,芹澤玄,濱田庸,力丸裕人,里見進
脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology 50(4), 443-448, 2010-08-25
NAID 10027742787

Antagonism of glycerol trinitrate activity by an inhibitor of glutathione S-transferase

[低用量]特に静脈を拡張させる　→　前負荷の軽減。血管抵抗は不変なので前負荷が減少した分、心拍出量が低下する。動脈の拡張は冠状動脈、顔面の血管、髄膜の細血管でおこる。後者2者は副作用(顔面の紅潮、頭痛)を来す機序と関係。(PHD.414)
[高用量]全身の細動脈と細静脈を拡張させる。これにより低血圧となり頻脈をおこす。けど、心不全の患者の場合はこれは起こらない(後負荷↓→十分なCO→交感神経緊張↓)。(PHD.414)