グルクロン酸抱合体

WordNet

undergo conjugation
unite chemically so that the product is easily broken down into the original compounds
formed by the union of two compounds; "a conjugated protein" (同)conjugated
of an organic compound; containing two or more double bonds each separated from the other by a single bond (同)conjugated
joined together especially in a pair or pairs (同)conjugated, coupled
(of a pinnate leaflet) having only one pair of leaflets
add inflections showing person, number, gender, tense, aspect, etc.; "conjugate the verb"

PrepTutorEJDIC

〈動詞〉'を'活用(変化)させる / 〈動詞が〉活用(変化)する / 〈単細胞生物が〉接合する / (特に対になって)結合した,接合の

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1. 米国の乳児に対する肺炎球菌結合型ワクチンを用いた一般的な予防注射が及ぼす影響impact of universal infant immunization with pneumococcal conjugate vaccines in the united states [show details]
…separately. Pneumococcal conjugate and polysaccharide vaccines also are discussed separately. Surveillance after the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) to the standard …
2. インフルエンザ菌b型感染の予防prevention of haemophilus influenzae type b infection [show details]
…with or without fever is a precaution to administration of Hib conjugate vaccine . Each dose of Hib conjugate vaccine is 0.5 mL. Hib conjugate vaccine is administered intramuscularly, usually in the anterolateral …
3. 髄膜炎菌ワクチンmeningococcal vaccines [show details]
…quadrivalent conjugate vaccines that contain capsular polysaccharide antigens from serogroups A, C, Y, and W conjugated to diphtheria toxoid or CRM197, respectively. The meningococcal conjugate vaccines elicit …
4. HIV感染成人における肺炎球菌ワクチンの接種pneumococcal immunization in hiv infected adults [show details]
…(PPSV23) to conjugate vaccine in HIV-infected patients. Although there are no clinical data on the use of 13-valent conjugate vaccine (PCV13), two prior clinical trials of the earlier 7-valent conjugate vaccine …
5. 免疫学的検査の一環として行う抗体機能の評価assessing antibody function as part of an immunologic evaluation [show details]
…antibodies to the protein component of the conjugate and thus represents a protein response. Conjugate vaccines – The other common type of vaccines are conjugate vaccines, which contain polysaccharide antigens …

English Journal

The influence of physicochemical properties on the reactivity and stability of acyl glucuronides †.

Camilleri P1, Buch A2, Soldo B2, Hutt AJ3.
Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2017 Oct 13:1-15. doi: 10.1080/00498254.2017.1384967. [Epub ahead of print]
PMID 28967291

Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice.

Shimizu M1, Suemizu H2, Mitsui M1, Shibata N3, Guengerich FP4, Yamazaki H1.
Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2017 Oct;47(10):844-848. doi: 10.1080/00498254.2016.1247218. Epub 2016 Nov 16.
PMID 27852146

A method for evaluating the pharmaceutical deconjugation potential in river water environments.

Azuma T1, Ishida M2, Hisamatsu K2, Yunoki A2, Otomo K2, Kunitou M2, Shimizu M2, Hosomaru K2, Mikata S2, Mino Y2.
Chemosphere.Chemosphere.2017 Aug;180:476-482. doi: 10.1016/j.chemosphere.2017.04.040. Epub 2017 Apr 10.
PMID 28431385

Japanese Journal

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump

JEDLITSCHKY G.
Cancer Res 56(5), 988-994, 1996
NAID 80008873204

Studies on the Enzyme Immunoassay of Bio-active Constituents Contained in Oriental Medicinal Drugs. V. : Preparation of Bovine Serum Albumin Conjugate and β-Galactosidase Labelled Antigen for Enzyme Immunoassay of 3β-(Monoglucuron-1'β-yl)-18β-glycyrrhetic Acid

金岡又雄,加藤弘巳,矢野三郎
Chemical & pharmaceutical bulletin 38(1), 221-224, 1990-01-25
… In order to prepare an immunogen for enzyme immunoassay of 3β-(monoglucuron-1'-β-yl)-18β-glycyrrhetic acid (3MGA), which was isolated from a patient with glycyrrhizin-induced pseudoaldosteronisms, benzyl glycyrrhetate (3) was allowed to react with an acetobromosugar (2) in the presence of silver carbonate to give benzyl 3β-(methyl2', 3', 4'-triacetyl-glucuron-1'β-yl)-glycyrrhetate (5) and methyl 3', 4'-diacetyl-α-1', 2'-O-[1-(benzyl glycyrrhet-3β-yl)-ethylidene]-D-glucuronate (4). …
NAID 110003628097

Studies on the enzyme immunoassay of bio-active constituents contained in oriental medicinal drugs. V. Preparation of bovine serum albumin conjugate and .BETA.-galactosidase labelled antigen for enzyme immunoassay of 3.BETA.-(monoglucuron-1'.BETA.-yl)-18.BETA.-glycyrrhetic acid.

金岡又雄,加藤弘巳,矢野三郎
ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 38(1), 221-224, 1990
… In order to prepare an immunogen for enzyme immunoassay of 3β-(monoglucuron-1'-β-yl)-18β-glycyrrhetic acid (3MGA), which was isolated from a patient with glycyrrhizin-induced pseudoaldosteronisms, benzyl glycyrrhetate (3) was allowed to react with an acetobromosugar (2) in the presence of silver carbonate to give benzyl 3β-(methyl2', 3', 4'-triacetyl-glucuron-1'β-yl)-glycyrrhetate (5) and methyl 3', 4'-diacetyl-α-1', 2'-O-[1-(benzyl glycyrrhet-3β-yl)-ethylidene]-D-glucuronate (4). …
NAID 130003771796