- acknowledged as a supposition; "given the engines condition, it is a wonder that it started" (同)granted
- an assumption that is taken for granted (同)presumption, precondition
- the act of excusing a mistake or offense (同)pardon
- compassionate feelings that support a willingness to forgive
- the quality of being granted as a supposition; of being acknowledged or assumed
- transfer possession of something concrete or abstract to somebody; "I gave her my money"; "can you give me lessons?"; "She gave the children lots of love and tender loving care"
- consent to engage in sexual intercourse with a man; "She gave herself to many men"
- occur; "what gives?"
- proffer (a body part); "She gave her hand to her little sister"
- the elasticity of something that can be stretched and returns to its original length (同)spring, springiness
- give or convey physically; "She gave him First Aid"; "I gave him a punch in the nose" (同)apply
- give entirely to a specific person, activity, or cause; "She committed herself to the work of God"; "give ones talents to a good cause"; "consecrate your life to the church" (同)dedicate, consecrate, commit, devote
- give as a present; make a gift of; "What will you give her for her birthday?" (同)gift, present
- convey, as of a compliment, regards, attention, etc.; bestow; "Dont pay him any mind"; "give the orders"; "Give him my best regards"; "pay attention" (同)pay
- dedicate; "give thought to"; "give priority to"; "pay attention to" (同)pay, devote
- bestow; "give homage"; "render thanks" (同)render
- convey or communicate; of a smile, a look, a physical gesture; "Throw a glance"; "She gave me a dirty look" (同)throw
- be flexible under stress of physical force; "This material doesnt give" (同)yield
- cause to happen or be responsible for; "His two singles gave the team the victory" (同)yield
- accord by verdict; "give a decision for the plaintiff"
- allow to have or take; "I give you two minutes to respond"
- cause to have, in the abstract sense or physical sense; "She gave him a black eye"; "The draft gave me a cold"
- convey or reveal information; "Give ones name"
- deliver in exchange or recompense; "Ill give you three books for four CDs"
- emit or utter; "Give a gulp"; "give a yelp"
- estimate the duration or outcome of something; "He gave the patient three months to live"; "I gave him a very good chance at success"
- execute and deliver; "Give bond"
- give (as medicine); "I gave him the drug"
- guide or direct, as by behavior of persuasion; "You gave me to think that you agreed with me"
- inflict as a punishment; "She gave the boy a good spanking"; "The judge gave me 10 years"
- leave with; give temporarily; "Can I give you my keys while I go in the pool?"; "Can I give you the children for the weekend?"
- manifest or show; "This student gives promise of real creativity"; "The office gave evidence of tampering"
- offer in good faith; "He gave her his word"
- perform for an audience; "Pollini is giving another concert in New York"
- present to view; "He gave the sign to start"
- propose; "He gave the first of many toasts at the birthday party"
- submit for consideration, judgment, or use; "give ones opinion"; "give an excuse"
- giveの過去分詞 / 定められた,一定の;(数学などで)与えられた / 《補語にのみ用いて》(…)する癖がある,(…に)熱中する《+『to』+『名』(do『ing』)》 / (公文書で何月何日に)作成された,交付された / …と仮定すると,もし…とすると / …があれば;…を考慮しても
- (…を)許すこと,容赦《+『of』+『名』》 / 寛大さ
- 名(first name, Christian name;「姓」(surname, family name, last name)に対する「名」に当たる)
- (無償で)〈物〉‘を'『与える』,あげる,贈る,提供する / 〈物〉‘を'『渡す』,手渡す(hand over) / 〈代金〉‘を'『支払う』 / 《抽象的なことを目的語にして》…‘を'『与える』,授ける,出す / 《『give』+『名』〈間〉+『名』〈直〉》…‘に'〈体の一部〉‘を'差し出す / …‘を'供給する;…‘を'生ずる,もたらす / 〈数量・兆候など〉‘を'示す / 《特に短い動作を表す名詞を目的語にしてgive a~の形で》…する / 〈会など〉‘を'催す,開く;〈劇など〉‘を'上演する / (…のために)…‘を'ささげる《+『名』+『for』(『to』)+『名』》 / (…に)〈努力・注意など〉‘を'向ける,注ぐ《+『名』+『to』+『名』》 / 《『give』+『名』+『to』do》…‘に'(…)させる / (…に)『物を与える』,寄付する《+『to』+『名』》 / 力に屈する,妥協する / (力を受けて)へこむ,たわむ;つぶれる / (材料などの)弾力性;(性格などの)順応性,協調性
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- Multidisciplinary management in Merkel cell carcinoma.
- Matkowski R, Lata E, Zietek M, Halon A, Forgacz J, Szynglarewicz B.Author information Department of Oncology, Division of Oncological Surgery, Wroclaw Medical University , Plac Hirszfelda 12, Wroclaw , Poland.AbstractHerein, the authors describe the experience with the treatment of Merkel cell carcinoma (MCC) and review the literature regarding MCC treatment regimens. Nine patients underwent treatment due to stage I, II, or III MCC. The median follow up was 39 months. In five cases, tumors were excised with skin margins of >2 cm, and skin margins were <2 cm in four patients. Local adjuvant radiotherapy (RT) was given to four patients, while three patients underwent local lymphadenectomy (LAD). Local recurrence occurred in four patients who did not undergo RT (among them three patients had excision margins <2 cm) after a mean time of 9 months. Despite retreatment, two of those patients developed metastases. Recurrence-free survival after primary therapy was achieved: (a) in three patients with stage I and II MCC treated surgically with excision margins <2 cm combined with RT or wide excision >2 cm alone and (b) in two patients with stage III MCC treated with wide excision and LAD combined with local and regional RT. A review of the literature supports the following recommendations: (a) excision with adequate margins combined with RT; (b) LAD with regional RT in cases of lymph node involvement; and (c) sentinel lymph node biopsy in patients without clinically suspicious lymph nodes.
- The Journal of dermatological treatment.J Dermatolog Treat.2014 Oct;25(5):409-14. doi: 10.3109/09546634.2012.756969. Epub 2013 Aug 13.
- Herein, the authors describe the experience with the treatment of Merkel cell carcinoma (MCC) and review the literature regarding MCC treatment regimens. Nine patients underwent treatment due to stage I, II, or III MCC. The median follow up was 39 months. In five cases, tumors were excised with skin
- PMID 23216365
- Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis.
- Kint C, Verstraeten N, Hofkens J, Fauvart M, Michiels J.Author information Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven , Kasteelpark Arenberg 20, 3001 Heverlee , Kasteelpark Arenberg 20, 3001 Heverlee and.AbstractAbstract Obg proteins (also known as ObgE, YhbZ and CgtA) are conserved P-loop GTPases, essential for growth in bacteria. Like other GTPases, Obg proteins cycle between a GTP-bound ON and a GDP-bound OFF state, thereby controlling cellular processes. Interestingly, the in vitro biochemical properties of Obg proteins suggest that they act as sensors for the cellular GDP/GTP pools and adjust their activity according to the cellular energy status. Obg proteins have been attributed a host of cellular functions, including roles in essential cellular processes (DNA replication, ribosome maturation) and roles in different stress adaptation pathways (stringent response, sporulation, general stress response). This review summarizes the current knowledge on Obg activity and function. Furthermore, we present a model that integrates the different functions of Obg by assigning it a fundamental role in cellular physiology, at the hub of protein and DNA synthesis. In particular, we believe that Obg proteins might provide a connection between different global pathways in order to fine-tune cellular processes in response to a given energy status.
- Critical reviews in microbiology.Crit Rev Microbiol.2014 Aug;40(3):207-24. doi: 10.3109/1040841X.2013.776510. Epub 2013 Mar 28.
- Abstract Obg proteins (also known as ObgE, YhbZ and CgtA) are conserved P-loop GTPases, essential for growth in bacteria. Like other GTPases, Obg proteins cycle between a GTP-bound ON and a GDP-bound OFF state, thereby controlling cellular processes. Interestingly, the in vitro biochemical propertie
- PMID 23537324
- Regulatory ecotoxicity testing of engineered nanoparticles: are the results relevant to the natural environment?
- Park S, Woodhall J, Ma G, Veinot JG, Cresser MS, Boxall AB.Author information Environment Department, University of York , Heslington, York, YO10 5DD , UK.AbstractAbstract Engineered nanoparticles (ENPs) will be released to the environment during use or following the disposal of ENP-containing products and concerns have been raised over the risks of ENPs to the environment. Many studies have explored the toxicity of ENPs to aquatic organisms but these studies have usually been performed with little understanding of the ENPs' behaviour in the test media and the relationship between behaviour in the media to behaviour in natural waters. This study evaluated and compared the aggregation behaviour of four model gold nanoparticle (NP) types (coated with neutral, negative, positive and amphoteric cappings) in standard ecotoxicity test media and natural waters. The effects of humic acid (HA) and test organisms on aggregation were also investigated. In standard media, positive and neutral NPs were stable, whereas amphoteric and negative NPs generally showed substantial aggregation. In natural waters, amphoteric NPs were generally found to be stable, neutral and positive NPs showed substantial aggregation while negative NPs were stable in some waters and unstable in others. HA addition stabilised the amphoteric NPs, destabilised the positive NPs and had no effect on stability of negative NPs. The presence of invertebrates generally lowered the degree of particle aggregation while macrophytes had no effect. Given the dramatically different behaviours of ENPs in various standard media and natural waters, current regulatory testing may either under- or overestimate the toxicity of nanomaterials to aquatic organisms. Therefore, there is a pressing need to employ ecotoxicity media which better represent the behaviour of ENPs in natural system.
- Nanotoxicology.Nanotoxicology.2014 Aug;8:583-92. doi: 10.3109/17435390.2013.818173. Epub 2013 Jul 16.
- Abstract Engineered nanoparticles (ENPs) will be released to the environment during use or following the disposal of ENP-containing products and concerns have been raised over the risks of ENPs to the environment. Many studies have explored the toxicity of ENPs to aquatic organisms but these studies
- PMID 23789836
- A grape and wine chemodiversity comparison of different appellations in Burgundy: Vintage vs terroir effects.
- Roullier-Gall C1, Boutegrabet L1, Gougeon RD2, Schmitt-Kopplin P3.Author information 1Institut Universitaire de la Vigne et du Vin, Jules Guyot, UMR A 02.102 PAM, Université de Bourgogne, Rue Claude Ladrey, BP 27877, 21078 Dijon Cedex, France; Helmholtz Zentrum Muenchen, Research unit Analytical BioGeoChemistry, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.2Institut Universitaire de la Vigne et du Vin, Jules Guyot, UMR A 02.102 PAM, Université de Bourgogne, Rue Claude Ladrey, BP 27877, 21078 Dijon Cedex, France. Electronic address: firstname.lastname@example.orgHelmholtz Zentrum Muenchen, Research unit Analytical BioGeoChemistry, Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany; Technische Universität Muenchen, Analytical Food Chemistry, Alte Akademie 10, 85354 Freising, Germany. Electronic address: email@example.com.AbstractThis study aimed at assessing the ability of high resolution Fourier Transform Ion Cyclotron Resonance - Mass Spectrometry (FTICR-MS) to differentiate grapes and corresponding wines from distinct vineyards managed by a same producer, according to complex chemical fingerprints. Grape extracts (at harvest) and corresponding wines from four different vineyards, sampled immediately after the alcoholic fermentation over three successive vintages, were analysed by FTICR-MS. Thousands of metabolites that are specific to a given vintage, or a given class (wine, skin or must) could be revealed, thus emphasising a strong vintage effect. The same wines were reanalyzed after a few years in bottle. Within the frame of this study, FTICR-MS along with multivariate statistical analyses could reveal significant terroir-discriminant families of metabolites from geographically close - though distinct - vineyards, but only after a few years of bottle ageing. It is supposed that the chemical composition of a wine holds memories of various environmental factors that have impacted its metabolic baggage at the moment of its elaboration. For the first time, such preliminary results indicate that non-targeted experiments can reveal such memories through terroir-related metabolic signatures of wines on a regional-scale that can potentially be as small as the countless "climats" of Burgundy.
- Food chemistry.Food Chem.2014 Jun 1;152:100-7. doi: 10.1016/j.foodchem.2013.11.056. Epub 2013 Nov 19.
- This study aimed at assessing the ability of high resolution Fourier Transform Ion Cyclotron Resonance - Mass Spectrometry (FTICR-MS) to differentiate grapes and corresponding wines from distinct vineyards managed by a same producer, according to complex chemical fingerprints. Grape extracts (at har
- PMID 24444912
- Use of Magnetic Resonance Imaging (MRI) to Study and Predict Fruit Splitting in Citrus
- Spintronic and Electronic Phenomena in Organic Molecules Measured with μSR
- Statistical-Mechanical Analysis of Semi-Supervised Learning and Its Optimal Scheduling
- given 【動】giveの過去分詞形 【名】 既知[既定]の事実、当然[当たり前]の... - アルクがお届けする進化するオンライン英和・和英辞書データベース。一般的な単語や連語から、イディオム、専門用語、スラングまで幅広く収録。
- プログレッシブ英和中辞典(第4版) - /ívn/[動]giveの過去分詞形. [形]1 定められた, 一定の, 既定のat a given place [time]｜定められた場所[時間]に.2 贈り物として与えられた, 贈られた；授けられた.3 《数学 ...
- givenとは。意味や和訳。[動]giveの過去分詞形. [形]1 定められた，一定の，既定のat a given place [time]定められた場所[時間]に.2 贈り物として与えられた，贈られた；授けられた.3 《数学》与えられた，所与の，既知の.4 [be given ...
- A 12-year-old child who is having difficulty in school is given an intelligence test.(behavioral science 4th ed p.64)