線維性組織球腫
WordNet
- (of meat) full of sinews; especially impossible to chew (同)sinewy, stringy, unchewable
PrepTutorEJDIC
- 繊維の,繊維状(質)の
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/03/15 06:51:01」(JST)
[Wiki en表示]
| Dermatofibroma |
| Classification and external resources |
| Specialty |
oncology |
| ICD-10 |
D23 (ILDS D23.L62) |
| ICD-9-CM |
216.9 |
| ICD-O |
M8830/0 |
| DiseasesDB |
29384 |
| eMedicine |
derm/96 |
| Patient UK |
Benign fibrous histiocytoma |
| MeSH |
D018219 |
|
[edit on Wikidata]
|
Benign fibrous histiocytomas (also known as dermal dendrocytoma,[1] dermatofibroma,[2] fibrous dermatofibroma,[2] fibrous histiocytoma,[2] fibroma simplex,[1] nodular subepidermal fibrosis,[1] and sclerosing hemangioma[1]) are benign skin growths.[3]
Contents
- 1 Presentation
- 2 Immunohistochemical staining
- 3 See also
- 4 References
Presentation
Dermatofibromas are hard solitary slow-growing papules (rounded bumps) that may appear in a variety of colours, usually brownish to tan; they are often elevated or pedunculated. A dermatofibroma is associated with the dimple sign; by applying lateral pressure, there is a central depression of the dermatofibroma. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Dermatofibromas can be found anywhere on the body, but most often they are found on the legs and arms.[4] They occur most often in women; the male to female ratio is about 1:4.[5] The age group in which they most commonly occur is 20 to 45 years.
Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.[5] They are composed of disordered collagen laid down by fibroblasts. Dermatofibromas are classed as benign skin lesions, meaning they are completely harmless, though they may be confused with a variety of subcutaneous tumours.[6] Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.[7]
Immunohistochemical staining
| Neoplasm |
CD34[1] |
Stromelysin-3[8] |
Factor XIIIa[5] |
| Dermatofibroma |
- |
+ |
+ |
| Dermatofibrosarcoma protuberans |
+ |
- |
- |
See also
- Dermatology
- Seborrheic keratosis
- Acrochordon, also called skin tags
- List of cutaneous conditions
References
- ^ a b c d e Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. [page needed]
- ^ a b c Freedberg; et al. (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill. p. 668. ISBN 0-07-138076-0.
- ^ "benign fibrous histiocytoma" at Dorland's Medical Dictionary
- ^ "dermatofibroma" at Dorland's Medical Dictionary
- ^ a b c Dermatofibroma at eMedicine
- ^ Jung, Kyu Dong; Lee, Dong-Youn; Lee, Joo-Heung; Yang, Jun-Mo; Lee, Eil-Soo (2011). "Subcutaneous Dermatofibroma". Annals of Dermatology. 23 (2): 254–7. doi:10.5021/ad.2011.23.2.254. PMC 3130878. PMID 21747634.
- ^ Hanly, A. J.; Jordà, M; Elgart, G. W.; Badiavas, E; Nassiri, M; Nadji, M (2006). "High proliferative activity excludes dermatofibroma: Report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors". Archives of pathology & laboratory medicine. 130 (6): 831–4. doi:10.1043/1543-2165(2006)130[831:HPAEDR]2.0.CO;2 (inactive 2017-01-15). PMID 16740036.
- ^ Kim, H.J.; Lee, J.Y.; Kim, S.H.; Seo, Y.J.; Lee, J.H.; Park, J.K.; Kim, M.H.; Cinn, Y.W.; Cho, K.H.; Yoon, T.Y. (2007). "Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: Comparison with factor XIIIa and CD34". British Journal of Dermatology. 157 (2): 319–24. doi:10.1111/j.1365-2133.2007.08033.x. PMID 17596171.
|
Connective/soft tissue tumors and sarcomas (ICD-O 8800–9059) (C45–C49/D17–D21, 171/214–215)
|
|
| Not otherwise specified |
- Soft-tissue sarcoma
- Desmoplastic small-round-cell tumor
|
|
| Connective tissue neoplasm |
| Fibromatous |
| Fibroma/fibrosarcoma: |
- Dermatofibrosarcoma protuberans
- Desmoplastic fibroma
|
|
| Fibroma/fibromatosis: |
- Aggressive infantile fibromatosis
- Aponeurotic fibroma
- Collagenous fibroma
- Diffuse infantile fibromatosis
- Familial myxovascular fibromas
- Fibroma of tendon sheath
- Fibromatosis colli
- Infantile digital fibromatosis
- Juvenile hyaline fibromatosis
- Plantar fibromatosis
- Pleomorphic fibroma
- Oral submucous fibrosis
|
|
| Histiocytoma/histiocytic sarcoma: |
- Benign fibrous histiocytoma
- Malignant fibrous histiocytoma
- Atypical fibroxanthoma
- Solitary fibrous tumor
|
|
|
| Myxomatous |
- Myxoma/myxosarcoma
- Cutaneous myxoma
- Superficial acral fibromyxoma
- Angiomyxoma
- Ossifying fibromyxoid tumour
|
|
| Fibroepithelial |
- Brenner tumour
- Fibroadenoma
- Phyllodes tumor
|
|
| Synovial-like |
- Synovial sarcoma
- Clear-cell sarcoma
|
|
|
| Lipomatous |
- Lipoma/liposarcoma
- Myelolipoma
- Myxoid liposarcoma
- PEComa
- Chondroid lipoma
- Intradermal spindle cell lipoma
- Pleomorphic lipoma
- Lipoblastomatosis
- Spindle cell lipoma
- Hibernoma
|
|
| Myomatous |
| general: |
|
|
| smooth muscle: |
|
|
| skeletal muscle: |
- Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma
- Alveolar rhabdomyosarcoma
|
|
- Leiomyoma
- Angioleiomyoma
- Angiolipoleiomyoma
- Genital leiomyoma
- Leiomyosarcoma
- Multiple cutaneous and uterine leiomyomatosis syndrome
- Multiple cutaneous leiomyoma
- Neural fibrolipoma
- Solitary cutaneous leiomyoma
- STUMP
|
|
|
| Complex mixed and stromal |
- Adenomyoma
- Pleomorphic adenoma
- Mixed Müllerian tumor
- Mesoblastic nephroma
- Wilms' tumor
- Malignant rhabdoid tumour
- Clear-cell sarcoma of the kidney
- Hepatoblastoma
- Pancreatoblastoma
- Carcinosarcoma
|
|
| Mesothelial |
- Mesothelioma
- Adenomatoid tumor
|
|
Tumors: Skin neoplasm, dermis (C44/D23, 173/216)
|
|
| Dermis |
- Benign fibrous histiocytoma/dermatofibrosarcoma protuberans
- Dermatofibrosarcoma protuberans
|
|
Subcutaneous
tumors |
Connective and
vascular |
- see Template:Soft tissue tumors and sarcomas, Template:Vascular tumors, Template:Myeloid malignancy (for mastocytosis)
|
|
| Other |
| urogenital: |
- Hirsuties coronae glandis
|
|
| neuro: |
- Solitary neurofibroma
- Cutaneous meningioma
- Ganglioneuroma
- Schwannoma
- Palisaded encapsulated neuroma
- Infantile neuroblastoma
- Neuroma cutis
|
|
| bone/cartilage: |
- Chordoma
- Extraskeletal chondroma
|
|
| nevus: |
- Nevus anemicus
- Nevus flammeus
- Nevus flammeus nuchae
- Nevus lipomatosus superficialis
- Nevus oligemicus
- Connective tissue nevus
- Midline nevus flammeus
- Porokeratotic eccrine ostial and dermal duct nevus
|
|
| histiocytoma: |
- Pleomorphic undifferentiated sarcoma
- Plexiform fibrohistiocytic tumor
- Progressive nodular histiocytoma
|
|
- Teratoma
- Adenoma sebaceum
- Metastatic carcinoma
- Giant-cell tumor of the tendon sheath
- Glomus tumor
- Granular cell tumor
- Carcinoid
- Desmoid tumor
- Neurothekeoma
- Angiokeratoma
- Zosteriform metastasis
- Keratinizing metaplasia
- Epithelioid sarcoma
|
|
|
UpToDate Contents
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English Journal
- Undifferentiated pleomorphic sarcoma of the vocal fold.
- Jeong CY1, Kim CS.
- Ear, nose, & throat journal.Ear Nose Throat J.2016 Dec;95(12):E12-E14.
- Undifferentiated pleomorphic sarcoma, previously called malignant fibrous histiocytoma, usually arises in the extremities and retroperitoneum. Primary laryngeal undifferentiated pleomorphic sarcoma is very rare, with only 63 cases having been reported in the literature as of 2015. The disease has a
- PMID 27929601
- Primary angiomatoid fibrous histiocytoma of the lung with mediastinal lymph node metastasis.
- Tay CK1, Koh MS1, Takano A2, Aubry MC3, Sukov WR4, Folpe AL5.
- Human pathology.Hum Pathol.2016 Dec;58:134-137. doi: 10.1016/j.humpath.2016.07.022. Epub 2016 Aug 18.
- Angiomatoid fibrous histiocytoma (AFH), a rare soft tissue tumor of borderline malignancy, typically occurs in the subcutis of the accessible soft tissues, most often in children and young adults. Lymph node and/or distant metastasis is seen in less than 2% of patients with AFH. Exceptionally rare e
- PMID 27544801
- Intracranial Angiomatoid Fibrous Histiocytoma: Case Report and Literature Review.
- Alshareef MA1, Almadidy Z2, Baker T3, Perry A4, Welsh CT3, Vandergrift WA 3rd5.
- World neurosurgery.World Neurosurg.2016 Dec;96:403-409. doi: 10.1016/j.wneu.2016.09.059. Epub 2016 Sep 22.
- BACKGROUND: Angiomatoid fibrous histiocytoma (AFH) is a rare and low-grade soft tissue lesion that typically arises from subcutaneous and deep dermal tissue of extremities. The first case was reported in 1979 by Enzinger and has since become known as a distinct entity. AFH has been increasingly repo
- PMID 27667574
Japanese Journal
- RFA, TACE治療後に腹膜播種を来たした肝細胞癌の１例
- 五十嵐 隆通,須納瀬 豊,平井 圭太郎,高橋 研吾,田中 和美,高橋 憲史,山崎 穂高,塚越 浩志,小川 博臣,吉成 大介,竹吉 泉,Igarashi Takamichi,Sunose Yutaka,Hirai Keitaro,Takahashi Kengo,Tanaka Kazumi,Takahashi Norifumi,Yamazaki Hodaka,Tsukagoshi Hiroshi,Ogawa Hiroomi,Yoshinari Daisuke,Takeyoshi Izumi
- The Kitakanto medical journal = 北関東医学 63(3), 267-272, 2013-08-01
- … 2007年 8月,腹部膨満と食欲不振を主訴に近医受診, CT精査で右側腹部,横行結腸間膜に接する最大径 12cm大の腹部腫瘤を認め,精査加療目的に当科紹介となった.画像上 gas-trointestinal stromal tumor,malignant fibrous histiocytoma,血管肉腫,肝細胞癌腹膜播種等を疑った.腫瘤は単発であったため, 2007年 9月,腫瘤摘出術を施行した.病理組織学的診断は肝細胞癌腹膜播種であった. …
- NAID 120005315267
- 顔面神経麻痺で発症した錐体骨malignant fibrous histiocytomaの1例
- 桑原 政志,江口 国輝,山口 智,光原 崇文,工田 昌也,武島 幸男,アマティア VJ,杉山 一彦,平川 勝洋,栗栖 薫
- Japanese Journal of Neurosurgery 22(4), 306-312, 2013
- … 頭頚部原発のmalignant fibrous histiocytoma (MFH) はまれである. …
- NAID 130003379614
- RFA, TACE治療後に腹膜播種を来たした肝細胞癌の１例
- 五十嵐 隆通,須納瀬 豊,平井 圭太郎,高橋 研吾,田中 和美,高橋 憲史,山崎 穂高,塚越 浩志,小川 博臣,吉成 大介,竹吉 泉
- 北関東医学 63(3), 267-272, 2013
- … 画像上gastrointestinal stromal tumor, malignant fibrous histiocytoma, 血管肉腫, 肝細胞癌腹膜播種等を疑った. …
- NAID 130003368253
Related Links
- der·ma·to·fi·bro·ma (der'mă'tō-fī-brō'mă), A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries, with scattered hemosiderin-pigmented and lipid macrophages. The ...
- Treatment and Prognosis Benign fibrous histiocytoma is treated by wide surgical excision, with 5-10% of cases recurring locally. Deeper and larger lesions have a higher rate of recurrence. More aggressive examples usually show the ...
★リンクテーブル★
[★]
- 英
- xanthofibroma
- 同
- 黄色肉芽腫 xanthogranuloma、線維性黄色腫 線維黄色腫 fibrous xanthoma、線維性組織球腫 fibrous histiocytoma
- 関
- 黄色腫、若年性黄色肉芽腫
[★]
- 英
- fibrous histiocytoma
- 関
- 硬化性血管腫、良性線維性組織球腫、悪性線維性組織球腫、皮膚線維腫、異型線維黄色腫、黄色線維腫、細網組織球腫
[★]
硬化性血管腫
- 関
- benign fibrous histiocytoma、dermatofibroma、fibrous histiocytoma、sclerosing hemangioma
[★]
悪性線維性組織球腫 MFH
[★]
類血管型線維性組織球腫
[★]
- 関
- fibrotic、filamentous