WordNet
- not dangerous to health; not recurrent or progressive (especially of a tumor)
- pleasant and beneficial in nature or influence; "a benign smile"; "the benign sky"; "the benign influence of pure air" (同)benignant
- kindness of disposition or manner; "the benign ruler of millions"; "benign intentions"
- (of meat) full of sinews; especially impossible to chew (同)sinewy, stringy, unchewable
PrepTutorEJDIC
- (心・表情などが)親切な,優しい / (事情・環境・気候などが)好適な,好都合な / 悪性でない
- 繊維の,繊維状(質)の
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/01/28 09:28:35」(JST)
[Wiki en表示]
Dermatofibroma |
Classification and external resources |
Specialty |
oncology |
ICD-10 |
D23 (ILDS D23.L62) |
ICD-9-CM |
216.9 |
ICD-O |
M8830/0 |
DiseasesDB |
29384 |
eMedicine |
derm/96 |
Patient UK |
Benign fibrous histiocytoma |
MeSH |
D018219 |
[edit on Wikidata]
|
Benign fibrous histiocytomas (also known as dermal dendrocytoma,[1] dermatofibroma,[2] fibrous dermatofibroma,[2] fibrous histiocytoma,[2] fibroma simplex,[1] nodular subepidermal fibrosis,[1] and sclerosing hemangioma[1]) are benign skin growths.[3]
Contents
- 1 Presentation
- 2 Immunohistochemical staining
- 3 See also
- 4 References
Presentation
Dermatofibromas are hard solitary slow-growing papules (rounded bumps) that may appear in a variety of colours, usually brownish to tan; they are often elevated or pedunculated. A dermatofibroma is associated with the dimple sign; by applying lateral pressure, there is a central depression of the dermatofibroma. Although typical dermatofibromas cause little or no discomfort, itching and tenderness can occur. Dermatofibromas can be found anywhere on the body, but most often they are found on the legs and arms.[4] They occur most often in women; the male to female ratio is about 1:4.[5] The age group in which they most commonly occur is 20 to 45 years.
Some physicians and researchers believe dermatofibromas form as a reaction to previous injuries such as insect bites or thorn pricks.[5] They are composed of disordered collagen laid down by fibroblasts. Dermatofibromas are classed as benign skin lesions, meaning they are completely harmless, though they may be confused with a variety of subcutaneous tumours.[6] Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.[7]
Immunohistochemical staining
Neoplasm |
CD34[1] |
Stromelysin-3[8] |
Factor XIIIa[5] |
Dermatofibroma |
- |
+ |
+ |
Dermatofibrosarcoma protuberans |
+ |
- |
- |
See also
- Dermatology
- Seborrheic keratosis
- Acrochordon, also called skin tags
- List of cutaneous conditions
References
- ^ a b c d e Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. [page needed]
- ^ a b c Freedberg; et al. (2003). Fitzpatrick's Dermatology in General Medicine (6th ed.). McGraw-Hill. p. 668. ISBN 0-07-138076-0.
- ^ "benign fibrous histiocytoma" at Dorland's Medical Dictionary
- ^ "dermatofibroma" at Dorland's Medical Dictionary
- ^ a b c Dermatofibroma at eMedicine
- ^ Jung, Kyu Dong; Lee, Dong-Youn; Lee, Joo-Heung; Yang, Jun-Mo; Lee, Eil-Soo (2011). "Subcutaneous Dermatofibroma". Annals of Dermatology. 23 (2): 254–7. doi:10.5021/ad.2011.23.2.254. PMC 3130878. PMID 21747634.
- ^ Hanly, A. J.; Jordà, M; Elgart, G. W.; Badiavas, E; Nassiri, M; Nadji, M (2006). "High proliferative activity excludes dermatofibroma: Report of the utility of MIB-1 in the differential diagnosis of selected fibrohistiocytic tumors". Archives of pathology & laboratory medicine. 130 (6): 831–4. doi:10.1043/1543-2165(2006)130[831:HPAEDR]2.0.CO;2 (inactive 2017-01-15). PMID 16740036.
- ^ Kim, H.J.; Lee, J.Y.; Kim, S.H.; Seo, Y.J.; Lee, J.H.; Park, J.K.; Kim, M.H.; Cinn, Y.W.; Cho, K.H.; Yoon, T.Y. (2007). "Stromelysin-3 expression in the differential diagnosis of dermatofibroma and dermatofibrosarcoma protuberans: Comparison with factor XIIIa and CD34". British Journal of Dermatology. 157 (2): 319–24. doi:10.1111/j.1365-2133.2007.08033.x. PMID 17596171.
Connective/soft tissue tumors and sarcomas (ICD-O 8800–9059) (C45–C49/D17–D21, 171/214–215)
|
|
Not otherwise specified |
- Soft-tissue sarcoma
- Desmoplastic small-round-cell tumor
|
|
Connective tissue neoplasm |
Fibromatous |
Fibroma/fibrosarcoma: |
- Dermatofibrosarcoma protuberans
- Desmoplastic fibroma
|
|
Fibroma/fibromatosis: |
- Aggressive infantile fibromatosis
- Aponeurotic fibroma
- Collagenous fibroma
- Diffuse infantile fibromatosis
- Familial myxovascular fibromas
- Fibroma of tendon sheath
- Fibromatosis colli
- Infantile digital fibromatosis
- Juvenile hyaline fibromatosis
- Plantar fibromatosis
- Pleomorphic fibroma
- Oral submucous fibrosis
|
|
Histiocytoma/histiocytic sarcoma: |
- Benign fibrous histiocytoma
- Malignant fibrous histiocytoma
- Atypical fibroxanthoma
- Solitary fibrous tumor
|
|
|
Myxomatous |
- Myxoma/myxosarcoma
- Cutaneous myxoma
- Superficial acral fibromyxoma
- Angiomyxoma
- Ossifying fibromyxoid tumour
|
|
Fibroepithelial |
- Brenner tumour
- Fibroadenoma
- Phyllodes tumor
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|
Synovial-like |
- Synovial sarcoma
- Clear-cell sarcoma
|
|
|
Lipomatous |
- Lipoma/liposarcoma
- Myelolipoma
- Myxoid liposarcoma
- PEComa
- Chondroid lipoma
- Intradermal spindle cell lipoma
- Pleomorphic lipoma
- Lipoblastomatosis
- Spindle cell lipoma
- Hibernoma
|
|
Myomatous |
general: |
|
|
smooth muscle: |
|
|
skeletal muscle: |
- Rhabdomyoma/rhabdomyosarcoma: Embryonal rhabdomyosarcoma
- Alveolar rhabdomyosarcoma
|
|
- Leiomyoma
- Angioleiomyoma
- Angiolipoleiomyoma
- Genital leiomyoma
- Leiomyosarcoma
- Multiple cutaneous and uterine leiomyomatosis syndrome
- Multiple cutaneous leiomyoma
- Neural fibrolipoma
- Solitary cutaneous leiomyoma
- STUMP
|
|
|
Complex mixed and stromal |
- Adenomyoma
- Pleomorphic adenoma
- Mixed Müllerian tumor
- Mesoblastic nephroma
- Wilms' tumor
- Malignant rhabdoid tumour
- Clear-cell sarcoma of the kidney
- Hepatoblastoma
- Pancreatoblastoma
- Carcinosarcoma
|
|
Mesothelial |
- Mesothelioma
- Adenomatoid tumor
|
Tumors: Skin neoplasm, dermis (C44/D23, 173/216)
|
|
Dermis |
- Benign fibrous histiocytoma/dermatofibrosarcoma protuberans
- Dermatofibrosarcoma protuberans
|
|
Subcutaneous
tumors |
Connective and
vascular |
- see Template:Soft tissue tumors and sarcomas, Template:Vascular tumors, Template:Myeloid malignancy (for mastocytosis)
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Other |
urogenital: |
- Hirsuties coronae glandis
|
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neuro: |
- Solitary neurofibroma
- Cutaneous meningioma
- Ganglioneuroma
- Schwannoma
- Palisaded encapsulated neuroma
- Infantile neuroblastoma
- Neuroma cutis
|
|
bone/cartilage: |
- Chordoma
- Extraskeletal chondroma
|
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nevus: |
- Nevus anemicus
- Nevus flammeus
- Nevus flammeus nuchae
- Nevus lipomatosus superficialis
- Nevus oligemicus
- Connective tissue nevus
- Midline nevus flammeus
- Porokeratotic eccrine ostial and dermal duct nevus
|
|
histiocytoma: |
- Pleomorphic undifferentiated sarcoma
- Plexiform fibrohistiocytic tumor
- Progressive nodular histiocytoma
|
|
- Teratoma
- Adenoma sebaceum
- Metastatic carcinoma
- Giant-cell tumor of the tendon sheath
- Glomus tumor
- Granular cell tumor
- Carcinoid
- Desmoid tumor
- Neurothekeoma
- Angiokeratoma
- Zosteriform metastasis
- Keratinizing metaplasia
- Epithelioid sarcoma
|
|
|
UpToDate Contents
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English Journal
- [Angiomatoid fibrous histiocytoma in children: 6 cases].
- Bohelay G1, Kluger N2, Battistella M3, Biaggi-Frassati A4, Plantier F5, Harraudeau A6, Avril MF7, Pedeutour F8, Fraitag S9.
- Annales de dermatologie et de venereologie.Ann Dermatol Venereol.2015 Sep 9. pii: S0151-9638(15)00486-X. doi: 10.1016/j.annder.2015.07.007. [Epub ahead of print]
- BACKGROUND: Angiomatoid fibrous histiocytoma (AFH) is a soft-tissue tumour of uncertain differentiation most often arising in the extremities of children and young adults. AFH is a little-known neoplasm and its rarity may result in it being misdiagnosed as either a reactive lesion or a benign or hig
- PMID 26363999
- Parotid Gland Nodular Fasciitis: A Clinicopathologic Series of 12 Cases with a Review of 18 Cases from the Literature.
- Gibson TC1, Bishop JA, Thompson LD.
- Head and neck pathology.Head Neck Pathol.2015 Sep;9(3):334-44. doi: 10.1007/s12105-014-0594-9. Epub 2014 Dec 4.
- Nodular fasciitis (NF), very uncommon in the parotid gland, is a benign myofibroblastic proliferation that may be mistaken for other neoplastic proliferations. The mass-like clinical presentation and histologic features result in frequent misclassification, resulting in inappropriate clinical manage
- PMID 25472697
Japanese Journal
- オトガイ部知覚鈍麻を合併した良性線維性組織球腫の1例
- 伊藤 耕,藤本 陽子,岩井 聡 [他]
- 日本口腔外科学会雑誌 = Japanese journal of oral and maxillofacial surgery 59(8), 532-536, 2013-08
- NAID 40019791952
- 吉福 孝介,馬越 瑞夫,黒野 祐一
- 耳鼻咽喉科臨床 105(8), 787-792, 2012
- … We report here in on a case of malignant fibrous histiocytoma (MFH) of the left postauricular region. … Based on these findings, the tumor was considered as benign and was resected under general anesthesia. …
- NAID 130002141242
- Benign fibrous histiocytoma arising from the intercostal space
- ARIKANOGLU Zulfu,AKBULUT Sami,BASBUG Murat,METEROGLU Fatih,SENOL Ayhan,MIZRAK Bulent
- General thoracic and cardiovascular surgery 59(11), 763-766, 2011-11-10
- NAID 10030549570
Related Links
- benign fibrous histiocytoma A benign tumour composed of primitive mesenchymal cells (macrophages or histiocytes) seen in the skin and soft tissues of the legs of young to middle-aged patients, more commonly women, usually in ...
- This tumor has been given the names benign fibrous hystiocytoma, fibrous histiocytoma, xanthofibroma, fibroxanthoma of bone, and primary xanthoma of bone. The author of this site prefes the name benign fibrous histiocytoma. There ...
★リンクテーブル★
[★]
硬化性血管腫
- 関
- benign fibrous histiocytoma、dermatofibroma、fibrous histiocytoma、sclerosing hemangioma
[★]
- 英
- benign fibrous histiocytoma
- 関
- 線維性組織球腫、硬化性血管腫、皮膚線維腫
[★]
- 関
- benignant、mild、mildly
[★]
- 関
- fibrotic、filamentous