上皮型Na+チャネル
WordNet
- direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
- a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
- a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
- (often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
- a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
- a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
- the 14th letter of the Roman alphabet (同)n
- of or belonging to the epithelium; "epithelial layer"
- official routes of communication; "you have to go through channels"
PrepTutorEJDIC
- 〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
- nitrogenの化学記号
UpToDate Contents
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English Journal
- Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis.
- Li G1, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, DeMaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z.
- American journal of respiratory cell and molecular biology.Am J Respir Cell Mol Biol.2014 Aug;51(2):210-22. doi: 10.1165/rcmb.2013-0353OC.
- Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJs) that regulate paracellular permeability to ions and solutes. Claudin 18, a member of the large claudin family, is highly expressed in lung alveolar epithelium. To elucidate the role of claudin 18 in alveolar
- PMID 24588076
- Electroneutral absorption of NaCl by the aldosterone-sensitive distal nephron: implication for normal electrolytes homeostasis and blood pressure regulation.
- Eladari D1, Chambrey R, Picard N, Hadchouel J.
- Cellular and molecular life sciences : CMLS.Cell Mol Life Sci.2014 Aug;71(15):2879-95. doi: 10.1007/s00018-014-1585-4. Epub 2014 Feb 21.
- Sodium absorption by the distal part of the nephron, i.e., the distal convoluted tubule, the connecting tubule, and the collecting duct, plays a major role in the control of homeostasis by the kidney. In this part of the nephron, sodium transport can either be electroneutral or electrogenic. The stu
- PMID 24556999
- Mechanism and synergism in epithelial fluid and electrolyte secretion.
- Hong JH1, Park S, Shcheynikov N, Muallem S.
- Pflügers Archiv : European journal of physiology.Pflugers Arch.2014 Aug;466(8):1487-99. doi: 10.1007/s00424-013-1390-1. Epub 2013 Nov 16.
- A central function of epithelia is the control of the volume and electrolyte composition of bodily fluids through vectorial transport of electrolytes and the obligatory H2O. In exocrine glands, fluid and electrolyte secretion is carried out by both acinar and duct cells, with the portion of fluid se
- PMID 24240699
Japanese Journal
- Characteristics and Pharmacological Regulation of Epithelial Na+ Channel (ENaC) and Epithelial Na+ Transport
- Marunaka Yoshinori
- Journal of Pharmacological Sciences, 2014
- … Epithelial Na+ transport participates in control of various body functions and conditions: e.g., homeostasis of body fluid content influencing blood pressure, control of amounts of fluids covering the apical surface of alveolar epithelial cells at appropriate levels for normal gas exchange, and prevention of bacterial/viral infection. …
- NAID 130004677804
- 樽野 陽幸,新里 直美,丸中 良典
- 膜 36(6), 300-307, 2011-11-01
- … The epithelial sodium channel (ENaC) forms a pathway for transpepithelial Na+ transport in a variety of epithelial tissues including the kidney collecting duct, airway epithelium, and distal colon. … In the kidney, ENaC plays a crucial role in body Na+ content and blood pressure control; …
- NAID 10030449943
- 上皮Naチャネル(ENaC)の機能制御と蛋白質分解 : Liddle症候群発症のメカニズム (特集 内分泌代謝制御と疾患にかかわる蛋白質分解)
Related Links
- Data in the table refer to the 2αβγ heteromer. There are several human diseases resulting from mutations in ENaC subunits, or their regulation, most of which lead to overexpression or under-expression of the channel in ...
- L. Schild, B.C. Rossier Institut de pharmacologie et de toxicologie de l'Université, Lausanne, Switzerland Laurent.Schild@ipharm.unil.ch, Bernard.Rossier@ipharm.unil.ch Definition The epithelial Na + channel (ENaC or amiloride-sensitive Na ...
★リンクテーブル★
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- 英
- epithelial Na channel, epithelial sodium channel, ENaC
- 同
- 上皮性Na+チャネル、ENaCチャネル、上皮性ナトリウムチャネル
- 関
- 尿細管
- 阻害剤:アミロライド (SP.743)
- 低濃度のNa溶液からでも効率よくNaを吸収できる (SP.743)
- 大腸(消化管では唯一) (SP.743)
- 腎臓の集合管、汗腺にも存在する????
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- 川床、川底。水路、河道
- 海峡
- 水管、導管
- 溝
- 経路、ルート。道筋、方向
- 関
- ion channel、ionic channel
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- 関
- epidermal、epithelia、epithelium
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