endocochlear potential

WordNet

1. existing in possibility; "a potential problem"; "possible uses of nuclear power" (同)possible
2. the inherent capacity for coming into being (同)potentiality, potency

PrepTutorEJDIC

1. 可能性のある,潜在的な / 可能性,潜在力 / 電位

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/08/26 09:21:40」(JST)

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The endocochlear potential (EP; also called endolymphatic potential) is the positive voltage of 80-100mV seen in the cochlear endolymphatic spaces. Within the cochlea the EP varies in the magnitude all along its length. When a sound is presented, the endocochlear potential changes either positive or negative in the endolymph, depending on the stimulus. The change in the potential is called the summating potential.

With the movement of the basilar membrane, a shear force is created and a small potential is generated due to a difference in potential between the endolymph (scala media- +80 mV) and the perilymph (vestibular and tympanic ducts- -70 mV). EP is highest in the basal turn of the Cochlea and decreases in the magnitude towards the apex. EP is highly dependent on the metabolism and ionic transport.

An acoustic stimulus produces a simultaneous change in conductance at the membrane of the receptor cell. Because there is a steep gradient (150 mV, changes in membrane conductance are accompanied by rapid influx and efflux of ions which in turn produce the receptor potential. This is known as the Battery Hypothesis. The receptor potential for each hair cell causes a release of neurotransmitter at its basal pole, which elicits excitation of the afferent nerve fibres. Research conducted by Salt et al. in 1987 revealed that the EP was generated by the basal cells of Stria Vascularis.

reference: The Endocohlear Potential, Cochlear Fluids Lab, Washington University.

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English Journal

• Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear.

• Sato MP1,2, Higuchi T1, Nin F1,3, Ogata G1,3, Sawamura S1, Yoshida T1,3,4, Ota T1, Hori K1, Komune S5, Uetsuka S1,6, Choi S7,8, Masuda M9, Watabe T10, Kanzaki S10, Ogawa K10, Inohara H6, Sakamoto S11, Takebayashi H12, Doi K2, Tanaka KF13, Hibino H1,3,8.
• Frontiers in molecular neuroscience.Front Mol Neurosci.2017 Sep 21;10:300. doi: 10.3389/fnmol.2017.00300. eCollection 2017.
• PMID 29018325

• Mechanisms involved in hearing disorders of thyroid ontogeny: a literature review.

• Andrade CLO1, Machado GC1, Fernandes LDC2, Albuquerque JM2, Casais-E-Silva LL3, Ramos HE4, Alves CAD5.
• Archives of endocrinology and metabolism.Arch Endocrinol Metab.2017 Sep 18:0. doi: 10.1590/2359-3997000000292. [Epub ahead of print]
• PMID 28977164

• Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear.

• Tan WJT1, Song L2,3,4, Graham M5, Schettino A6, Navaratnam D7,8, Yarbrough WG1,9, Santos-Sacchi J1,8,10, Ivanova AV1.
• Antioxidants & redox signaling.Antioxid Redox Signal.2017 Sep 10;27(8):489-509. doi: 10.1089/ars.2016.6851. Epub 2017 Mar 9.
• PMID 28135838

Japanese Journal

• 鳥類内耳tegmentum vasculosum の構造と機能

• 池田 理佐,乙野 剛史,池田 直矢,齋藤 昇,安藤 元紀
• 岡山実験動物研究会報 33, 26-30, 2017-04
• … In spite of the importance of endocochlear DC potential (EP) and the K+-rich endolymph for the avian cochlea, the structure and function of the tegmentum vasculosum (TV) has not yet been fully elucidated, compared with those of the stria vascularis in the mammalian cochlea. …
• NAID 120006223676

• Tricellular Tight Junctions in the Inner Ear

• Kitajiri Shin-ichiro,Katsuno Tatsuya
• BioMed Research International 2016, 2016-04-03
• … In the inner ear, the barrier function of TJs is indispensable for the separation of the endolymphatic and perilymphatic spaces, which is essential for the generation and maintenance of the endocochlear potential (EP). …
• NAID 120005770756

• Ca²⁺-mediated regulation of endocochlear potential

• Moriyama-Nagai Ayako,Kawashima Nobuhisa,Hayashi Teruyuki,Ito Hiromi,Watanabe Kikuko,Morita Akemi,Kubota Takahiro
• 甲子園大学紀要 (43), 1-7, 2016
• NAID 40020816188

Related Pictures

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★リンクテーブル★

リンク元	「EP」「蝸牛内直流電位」
関連記事	「potential」

「EP」

　　[★]

• 慢性好酸球性肺炎 eosinophilic pneumonia
• エリスロポエチン erythropoietin
• 蝸牛内直流電位 endocochlear potential
• 粘膜上皮 mucosal epithelium mucosal epithelia -> epitheliumの略としてEP

「蝸牛内直流電位」

　　[★]

英

endocochlear potential EP

「potential」

　　[★]

• n.

• 電位、可能性、ポテンシャル

• adj.

• 潜在的な、可能な、有望な

関

capability、capable、electric potential、electrical potential、feasibility、feasible、latently、likelihood、odds、possibility、possible、potentiality、potentially、probability、promising、voltage