WordNet
- in the right manner; "please do your job properly!"; "cant you carry me decent?" (同)decently, decent, in good order, right, the right way
- in an accurate manner; "the flower had been correctly depicted by his son"; "he guessed right" (同)right, aright
- to an undue degree; "she was unduly pessimistic about her future"
PrepTutorEJDIC
- 正しく,当然に,順当に
- 『適切に』,妥当に / 基準にかなって,正式に / 厳密に,正確に / 《英話》完全に,ひどく
- 正しく,正確に;正確に言えば
- 過度に,はなはだしく;不当に
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/11/26 16:18:40」(JST)
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English Journal
- Antitubercular drug-induced violent suicide of a hospitalised patient.
- Behera C, Krishna K, Singh HR.Author information Department of Forensic Medicine, All India Institute of Medical Sciences, New Delhi, India.AbstractWe present a case where a young adult male, on treatment for multidrug-resistance tuberculosis (MDR-TB), developed drug-induced psychosis. The psychiatric symptoms were ascribed to the anti-TB drug and were duly withdrawn by the treating doctors and supplemented with other drugs. However, the victim continued to have psychiatric symptoms and committed suicide in the hospital. He ended his life in a violent manner by stabbing and cutting himself with a kitchen knife. The case is briefly reported in this paper with a discussion on anti-TB drug-induced psychiatric effects leading to suicide.
- BMJ case reports.BMJ Case Rep.2014 Jan 6;2014(jan06_1). pii: bcr2013201469. doi: 10.1136/bcr-2013-201469.
- We present a case where a young adult male, on treatment for multidrug-resistance tuberculosis (MDR-TB), developed drug-induced psychosis. The psychiatric symptoms were ascribed to the anti-TB drug and were duly withdrawn by the treating doctors and supplemented with other drugs. However, the victim
- PMID 24395874
- Phytoestrogens selective for the estrogen receptor beta exert anti-androgenic effects in castration resistant prostate cancer.
- Thelen P, Wuttke W, Seidlová-Wuttke D.Author information University Medical Center Göttingen, Georg-August-University, Department of Urology, 37099 Göttingen, Germany. Electronic address: pthelen@gwdg.de.AbstractProstate cancer is the leading cause of cancer death in men of the Western world. A castration-resistant prostate cancer (CRPC) eventually will arise when a local restricted prostate carcinoma was not cured duly by radical prostatectomy or radiation therapy. Although androgen ablation therapies are considered the gold standard for treatments of advanced prostate cancer there is no curative therapy available at present. In previous pre-clinical and clinical trials several phytoestrogens were investigated for their anticancer potential in various models for prostate cancer. Phytoestrogens feature tumour preventive characteristics and most probably are involved in the low incidence rate of hormone related cancers in Asian countries. Phytoestrogens such as isoflavones can have a marked impact on the most essential therapy target of CRPC i.e. the androgen receptor. Furthermore, functional analyses solidified the notion of such drugs as androgen antagonistic. Phytoestrogens commonly feature low toxicity combined with a potential of targeted therapy. Thus, these drugs qualify for conceivable implementation in prostate cancer patients under active surveillance. In addition, relapse prevention with these drugs after radical prostatectomy or radiation therapy might be considered. This article is part of a Special Issue entitled 'Phytoestrogens'.
- The Journal of steroid biochemistry and molecular biology.J Steroid Biochem Mol Biol.2014 Jan;139:290-3. doi: 10.1016/j.jsbmb.2013.06.009. Epub 2013 Jul 17.
- Prostate cancer is the leading cause of cancer death in men of the Western world. A castration-resistant prostate cancer (CRPC) eventually will arise when a local restricted prostate carcinoma was not cured duly by radical prostatectomy or radiation therapy. Although androgen ablation therapies are
- PMID 23872207
- Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.
- Singh P, Alex JM, Bast F.Author information Centre for Biosciences, School of Basic and Applied Science, Central University of Punjab, Bathinda, 151001, Punjab, India.AbstractInsulin and insulin-like growth factor (IGF) signaling system, commonly known for fine-tuning numerous biological processes, has lately made its mark as a much sought-after therapeutic targets for diabetes and cancer. These receptors make an attractive anticancer target owing to their overexpression in variety of cancer especially in prostate and breast cancer. Inhibitors of IGF signaling were subjected to clinical cancer trials with the main objective to confirm the effectiveness of these receptors as a therapeutic target. However, the results that these trials produced proved to be disappointing as the role played by the cross talk between IGF and insulin receptor (IR) signaling pathways at the receptor level or at downstream signaling level became more lucid. Therapeutic strategy for IGF-1R and IR inhibition mainly encompasses three main approaches namely receptor blockade with monoclonal antibodies, tyrosine kinase inhibition (ATP antagonist and non-ATP antagonist), and ligand neutralization via monoclonal antibodies targeted to ligand or recombinant IGF-binding proteins. Other drug-discovery approaches are employed to target IGF-1R, and IR includes antisense oligonucleotides and recombinant IGF-binding proteins. However, therapies with monoclonal antibodies and tyrosine kinase inhibition targeting the IGF-1R are not evidenced to be satisfactory as expected. Factors that are duly held responsible for the unsuccessfulness of these therapies include (a) the existence of the IR isoform A overexpressed on a variety of cancers, enhancing the mitogenic signals to the nucleus leading to the endorsement of cell growth, (b) IGF-1R and IR that form hybrid receptors sensitive to the stimulation of all three IGF axis ligands, and (c) IGF-1R and IR that also have the potential to form hybrid receptors with other tyrosine kinase to potentiate the cellular transformation, tumorigenesis, and tumor vascularization. This mini review is a concerted effort to explore and fathom the well-recognized roles of the IRA signaling system in human cancer phenotype and the main strategies that have been so far evaluated to target the IR and IGF-1R.
- Medical oncology (Northwood, London, England).Med Oncol.2014 Jan;31(1):805. doi: 10.1007/s12032-013-0805-3. Epub 2013 Dec 14.
- Insulin and insulin-like growth factor (IGF) signaling system, commonly known for fine-tuning numerous biological processes, has lately made its mark as a much sought-after therapeutic targets for diabetes and cancer. These receptors make an attractive anticancer target owing to their overexpression
- PMID 24338270
Japanese Journal
- On Simplified Mechanical Models for Body Divergence and Flutter
- SUGIYAMA Yoshihiko,OHSHIMA Tsukasa
- TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES 56(1), 42-48, 2013
- … Secondly, after having a duly simplified mechanical model, effects of mass distribution, stiffness distribution and location of a stabilizer fin are discussed. …
- NAID 130003364823
- 専決処分制度について
- 角田 雅博
- 関東学園大学法学紀要 21(1), 53-82, 2012-03
- NAID 40019227071
- 通常実施権の対抗要件制度について (特集 産業財産権制度の現状と課題)
- 茶園 成樹
- 特許研究 (51), 6-13, 2011-03
- NAID 40018808267
Related Pictures
★リンクテーブル★
| リンク元 | 「properly」「correctly」「正しく」 |
| 拡張検索 | 「unduly」 |
「properly」
- adv.
- 関
- ad libitum、adequate、adequately、appropriate、appropriately、correctly、duly、fittingly、neatly、pertinent、proper、reasonable、rigorously、strict、strictly、stringent、stringently、suitably
「correctly」
- adv.
- 正しく、正確に。適切に。礼儀にかなって。(文修飾)正確には、正確に言えば
- 関
- accurate, accurately, correct, duly, exact, exactly, faithfully, nicely, precise, precisely, properly
「正しく」
「unduly」
- 過度に、不当に