WordNet

a continuous tube formed by a row of elongated cells lacking intervening end walls
an enclosed conduit for a fluid
a bodily passage or tube lined with epithelial cells and conveying a secretion or other substance; "the tear duct was obstructed"; "the alimentary canal"; "poison is released through a channel in the snakes fangs" (同)epithelial duct, canal, channel
of or involving the pancreas; "pancreatic cancer"

PrepTutorEJDIC

送水管;(建物・船などの)通気管;(地下ケーブルなどの)ダクト / (体液を運ぶ)導管,(植物が水・空気を運ぶ)導管
膵臓の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/08/03 02:54:38」(JST)

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1. Bile ducts: 2. Intrahepatic bile ducts, 3. Left and right hepatic ducts, 4. Common hepatic duct, 5. Cystic duct, 6. Common bile duct, 7. Ampulla of Vater, 8. Major duodenal papilla
9. Gallbladder, 10–11. Right and left lobes of liver. 12. Spleen.
13. Esophagus. 14. Stomach. 15. Pancreas: 16: Accessory pancreatic duct, 17: Pancreatic duct.
18. Small intestine: 19. Duodenum, 20. Jejunum
21–22: Right and left kidneys (silhouette).

The anterior border of the liver is lifted upwards (brown arrow). Gallbladder with Longitudinal section, pancreas and duodenum with frontal one. Intrahepatic ducts and stomach in transparency.

The pancreatic duct, or duct of Wirsung (also, the major pancreatic duct due to the existence of an accessory pancreatic duct), is a duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. There are many anatomical variants reported but these are quite rare.^[1]

The duct of Wirsung is named after its discoverer, the German anatomist Johann Georg Wirsung (1589–1643).^[2]

Accessory pancreatic duct

Most people have just one pancreatic duct. However, some have an additional accessory pancreatic duct, called the Duct of Santorini. Accessory pancreatic duct can be functional or non-functional and may open separately into the second part of the duodenum ^[3]^[4]

Clinical significance

Compression, obstruction or inflammation of the pancreatic duct may lead to acute pancreatitis. The most common cause for obstruction is choledocholithiasis, or gallstones in the common bile duct. Obstruction can also be due to duodenal inflammation in Crohn's disease.^[5] A gallstone may get lodged in the constricted distal end of the ampulla of Vater, where it blocks the flow of both bile and pancreatic juice into the duodenum. Bile backing up into the pancreatic duct may initiate pancreatitis.^[6]

Pancreatic ductal carcinoma is a common form of pancreatic cancer.

Additional images

ERCP image showing the pancreatic duct and biliary tree.
Accessory digestive system.
Interior of the descending portion of the duodenum, showing bile papilla.
Pancreas of a human embryo of five weeks.
Pancreas of a human embryo at end of sixth week.
Pancreatic duct Deep dissection.Anterior view.

References

^ Goel, Shivi; Rustagi, SM; Saha, S; Mehta, V; Suri, RK; Rath, G (July 2015). "Aberrant pancreatic ductal organisation: a case report.". Surgical and radiologic anatomy: SRA. 37 (5): 543–6. doi:10.1007/s00276-015-1474-z. PMID 25840941.
^ doctor/2941 at Who Named It?
^ Moore KL, Dalley AF. 2006. Clinically Oriented Anatomy. 5th Ed. Lippincott Williams & Wilkins. p 287.
^ 1. Mchonde GJ, Gesase AP. Termination pattern of main and accessory pancreatic ducts among Tanzanians. Anatomy Journal of Africa. 2014; 3(1):223-227.
^ http://www.gastro.org/user-assets/html/eDigest/2005/December/1/120105.htm
^ Moore, Keith L.; Dalley, Arthur F. (2006). Clinically Oriented Anatomy, Fifth Edition. Lippincott Williams & Wilkins. p. 287. ISBN 0-7817-3639-0.

UpToDate Contents

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1. 動脈管開存症の臨床症状および診断 clinical manifestations and diagnosis of patent ductus arteriosus
2. 動脈管開存症のマネージメント management of patent ductus arteriosus
3. 早産児における動脈管開存症の病態生理、臨床症状、および診断 pathophysiology clinical manifestations and diagnosis of patent ductus arteriosus in premature infants
4. 血管輪 vascular rings
5. 胎児の発育遅延：評価およびマネージメント fetal growth restriction evaluation and management

English Journal

A Case of Pancreatic Adenosquamous Carcinoma Obstructing the Common Bile and Pancreatic Ducts, Duodenum, and Gastric Outlet.

Kurdi YM1, Peck JR, Roth R, Conwell DL.
Pancreas.Pancreas.2016 Apr;45(3):e9-e10. doi: 10.1097/MPA.0000000000000519.
PMID 26863381

Effect of All-Trans Retinoic Acid on the Pancreas of Streptozotocin-Induced Diabetic Rat.

Eltony SA1, Elmottaleb NA2, Gomaa AM2, Anwar MM2, El-Metwally TH3.
Anatomical record (Hoboken, N.J. : 2007).Anat Rec (Hoboken).2016 Mar;299(3):334-51. doi: 10.1002/ar.23307. Epub 2016 Jan 18.
All-trans Retinoic acid (atRA) is instructive for the development of endocrine pancreas and is an integral component of β-cell induction protocols. We showed that atRA induces glucose-responsive endocrine transdifferentiation of pleomorphic pancreatic ductal adenocarcinoma cells in vitro. This stud
PMID 26704900

Vascular and ductal elastotic changes in pancreatic cancer.

Lakiotaki E1, Sakellariou S1, Evangelou K2, Liapis G1, Patsouris E1, Delladetsima I1.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.APMIS.2016 Mar;124(3):181-7. doi: 10.1111/apm.12482. Epub 2015 Dec 1.
This study aims to identify and define the type and frequency of elastotic alterations of vessels and ducts in pancreatic ductal carcinoma (PDAC) and evaluate its diagnostic significance. Representative tissue from 36 Whipple specimens, stained with Verhoeff's Van-Gieson, was studied focusing on the
PMID 26619815

Japanese Journal

先天性胆道拡張症の手術時に発見された重複総胆管の1例

日本小児外科学会雑誌 48(4), 731-737, 2012-06-20
NAID 110009470927

鶏の比較解剖学的並びに局所解剖学的研究 : LXXVIII. 膵葉の区分および膵管分布について

日本獸醫學雜誌 36(3), 213-229, 1974-06-25
NAID 110003977749

鶏の比較解剖学的並びに局所解剖学的研究 : LXXVIII. 膵葉の区分および膵管分布について

日本獸醫學雜誌(The Japanese Journal of Veterinary Science) 36(3), 213-229, 1974
NAID 130003480770

「膵管」

Pancreatic duct
	The pancreatic duct.
Details
Precursor	Pancreatic bud
Identifiers
Latin	ductus pancreaticus
MeSH	A03.734.667
TA	A05.9.01.015
FMA	10419
	Anatomical terminology [edit on Wikidata]