WordNet
- intend (something) to move towards a certain goal; "He aimed his fists towards his opponents face"; "criticism directed at her superior"; "direct your anger towards others, not towards yourself" (同)aim, place, direct, point
- sports equipment consisting of an object set up for a marksman or archer to aim at (同)butt
- a reference point to shoot at; "his arrow hit the mark" (同)mark
- the location of the target that is to be hit (同)target area
- see for the first time; make a discovery; "Who discovered the North Pole?"
- make a discovery, make a new finding; "Roentgen discovered X-rays"; "Physicists believe they found a new elementary particle" (同)find
- make a discovery; "She found that he had lied to her"; "The story is false, so far as I can discover" (同)find
- the act of discovering something (同)find, uncovering
- a productive insight (同)breakthrough, find
- (law) compulsory pretrial disclosure of documents relevant to a case; enables one side in a litigation to elicit information from the other side concerning the facts in the case
- something that is discovered
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
PrepTutorEJDIC
- (鉄砲などの)『標的』,的,攻撃目標 / (批評・軽べつなどの)的,種《+of+名》 / (行為などの)目標,到達目標
- 〈今まで知らなかった物・場所〉‘を'『発見する』,見付ける / 〈今まで知らなかった事〉‘を'発見する,悟る
- 〈U〉『発見』;〈C〉発見した物(事)
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
UpToDate Contents
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- 1. 抗マラリア剤：概要 antimalarial drugs an overview
- 2. 薬物アレルギー患者へのアプローチ an approach to the patient with drug allergy
- 3. 成人における薬物中毒への一般的アプローチ general approach to drug poisoning in adults
- 4. リウマチ性疾患における免疫抑制剤および疾患修飾剤の使用の概要 overview of the use of immunosuppressive and disease modifying drugs in the rheumatic diseases
- 5. Liver transplantation in adults: Overview of immunosuppression
English Journal
- Expression of ustR and the Golgi protease KexB are required for ustiloxin B biosynthesis in Aspergillus oryzae.
- Yoshimi A1, Umemura M2, Nagano N3, Koike H4, Machida M5, Abe K6,7.
- AMB Express.AMB Express.2016 Dec;6(1):9. doi: 10.1186/s13568-016-0181-4. Epub 2016 Feb 3.
- Ustiloxin B, originally isolated from the fungus Ustilaginoidea virens, is a known inhibitor of microtubule assembly. Ustiloxin B is also produced by Aspergillus flavus and is synthesized through the ribosomal peptide synthesis pathway. In A. flavus, the gene cluster associated with ustiloxin B prod
- PMID 26842395
- P-glycoprotein differentially affects escitalopram, levomilnacipran, vilazodone and vortioxetine transport at the mouse blood-brain barrier in vivo.
- Bundgaard C1, Eneberg E2, Sánchez C3.
- Neuropharmacology.Neuropharmacology.2016 Apr;103:104-11. doi: 10.1016/j.neuropharm.2015.12.009. Epub 2015 Dec 15.
- P-glycoprotein (P-gp)-mediated brain efflux of xenobiotics is a well-known process, which may result in suboptimal target engagement and consequently reduced efficacy of drugs exerting their therapeutic effects in the central nervous system. In the present study the role of P-gp in transport across
- PMID 26700248
- Ligand-based modeling of diverse aryalkylamines yields new potent P-glycoprotein inhibitors.
- AlQudah DA1, Zihlif MA1, Taha MO2.
- European journal of medicinal chemistry.Eur J Med Chem.2016 Mar 3;110:204-23. doi: 10.1016/j.ejmech.2016.01.034. Epub 2016 Jan 21.
- The P-glycoprotein (P-gp) efflux pump has an important role as a natural detoxification system in many types of normal and cancer cells. P-gp is implicated in multiple drug resistance (MDR) exhibited by several types of cancer against a multitude of anticancer chemotherapeutic agents, and therefore,
- PMID 26840362
Japanese Journal
- ケミカルバイオロジーと新規分子標的薬 (特集 固形がんの分子標的薬 : 基礎研究から創薬・開発・臨床まで) -- (がん分子標的治療の基礎)
- 日本臨床 73(8), 1273-1280, 2015-08
- NAID 40020541084
- 創薬ターゲットとしての核−細胞質間物質輸送
- バイオサイエンスとインダストリー 73(4), 288-291, 2015
- NAID 40020536325
- インクジェットテクノロジーを利用して親水性ゲルで結晶をループに固定する技術
- 日本結晶学会誌 57(3), 198-202, 2015
- NAID 130005085905
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| 関連記事 | 「drug target」「discover」「target」「discovery」「targeting」 |
「drug target」
「discover」
- v.
- 発見する、見出す
「target」
- n.
- v.
「discovery」
- n.