Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/27 18:34:23」(JST)

wiki en

Dermatochalasis is a medical condition, defined as an excess of skin in the upper or lower eyelid, also known as "baggy eyes."^[1] It may be either an acquired or a congenital condition. It is generally treated with blepharoplasty.

Pathophysiology

Dermatochalasis is caused by a loss of elasticity in the connective tissue supporting the structure of the front portion of the eyelid.^[2] Normally, in Caucasians, the orbicularis muscle and overlying skin form a crease near the tarsal border.^[2] In dermatochalasis, the excess tissues hangs down, over the front edge of the eyelid. The excess tissue can sometimes obstruct the visual field, especially the superior visual field.^[1] In severe cases, it may obstruct as much as 50 percent of the superior visual field.^[3]

Treatment

If dermatochalasis is severe enough to obstruct the peripheral or superior visual fields, then it may be treated with a surgical procedure called blepharoplasty.^[2] In blepharoplasty surgery, excess skin, muscle and fat are removed. While the improvement of vision is an indication for blepharoplasty on the superior eyelid, if the visual fields are not obstructed, it may be performed for cosmetic reasons. In general, blepharoplasty of the inferior eyelid is considered cosmetic, as dermatochalasis in the lower eyelid does not interfere with vision.^[2]

Associated conditions

People with dermatochalasis often also have blepharitis, a condition caused by the plugging of glands in the eye that produce lubricating fluid (meibomian glands).^[3] Dermatochalasis can be severe enough that it pushes the eyelashes into the eye, causing entropion.^[3]

Weakness in the orbital septum may cause the herniation of the orbital fat pads.^[2] This is observed as the presence of bulges (fat pads) in the soft tissue of the baggy eyes.^[2]

Epidemiology

Dermatochalasis commonly affects the elderly, although sometimes it is congenitally acquired. The elderly version may begin to develop as early as 40 years of age, and it continues to progress with age.^[3] The congenital version may begin around 20 years of age.^[3] There is no racial predisposition towards developing dermatochalasis, and men and women are equally affected.^[3]

References

^ ^a ^b Goldman, Lee (2011). Goldman's Cecil Medicine (24th ed.). Philadelphia: Elsevier Saunders. p. 2426. ISBN 1437727883.
^ ^a ^b ^c ^d ^e ^f Cunningham, Emmett T.; Paul Riordan-Eva (2011). "Chapter 4: Lids & Lacrimal Apparatus". Vaughan & Asbury's general ophthalmology. (18th ed.). New York: McGraw-Hill Medical. ISBN 978-0071634205.
^ ^a ^b ^c ^d ^e ^f Gilliland, Grant. "Dermatochalasis". WebMD, LLC. Medscape. Retrieved 1 December 2012.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 眼瞼下垂症の概要 overview of ptosis

English Journal

Eyebrow Position Following Upper Blepharoplasty.

Dar SA1, Rubinstein TJ2, Perry JD2.
Orbit (Amsterdam, Netherlands).Orbit.2015 Dec;34(6):327-30. doi: 10.3109/01676830.2015.1078375. Epub 2015 Oct 27.
PURPOSE: To evaluate the effect of upper blepharoplasty on eyebrow height, accounting for ocular dominance, fat excision, change in MRD1, and degree of dermatochalasis.METHODS: Retrospective review of patients undergoing upper blepharoplasty between January 2013 and July 2014. Patients with a prior
PMID 26505314

[Multiple bladder diverticula caused by occipital horn syndrome].

Legros L1, Revencu N2, Nassogne MC3, Wese FX1, Feyaerts A4.
Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie.Arch Pediatr.2015 Nov;22(11):1147-50. doi: 10.1016/j.arcped.2015.07.017. Epub 2015 Sep 16.
We report on the case of a child who presented with recurrent, multiple, and voluminous bladder diverticula. Bladder diverticula are defined as a herniation of the mucosa through the bladder muscle or the detrusor. Causes are numerous and diverticula can be classified into primary congenital diverti
PMID 26386812

Pemetrexed-Associated Eyelid Edema: Effective Treatment by Excision of Lymphedematous Eyelid Tissue.

Mangla N1, Carlson A, Wakil A, Wu N, Wladis EJ.
Ophthalmic plastic and reconstructive surgery.Ophthal Plast Reconstr Surg.2015 Nov-Dec;31(6):e155-7. doi: 10.1097/IOP.0000000000000186.
Pemetrexed is an antimetabolite agent that inhibits multiple folate-requiring enzymes and is used in the treatment of mesothelioma and non-small-cell lung cancer. One of its toxicities is isolated cutaneous swelling affecting the eyelids and/or orbit. The pathologic assessment or its management has
PMID 24911536

Japanese Journal

拡大眉毛下皮膚切除術 (特集眼瞼の美容外科手術手技アトラス) -- (上眼瞼形成術)

一瀬晃洋
Pepars (87), 67-72, 2014-03
NAID 40020032598

退行性上眼瞼皮膚弛緩症に対する眉毛下皮膚切除術 (特集眼瞼の退行性疾患に対する眼形成外科手術) -- (上眼瞼の退行性(加齢性)疾患)

村上正洋
ペパーズ (51), 52-61, 2011-03
NAID 40018768223

症例皮膚切除のデザインを工夫した高度の開瞼困難を有する眼瞼皮膚弛緩症の1例

山内誠,四ツ柳高敏,山下建 [他]
形成外科 54(1), 73-78, 2011-01
NAID 40017657300

Related Pictures

DERMATOCHALASIS and PTOSIS (toe-sis Dermatochalasis Eyelid disorder resized Ptosis: Dermatochalasis Bilateral dermatochalasis For > Dermatochalasis Vs Blepharochalasis Baggy Eyelids (Dermatochalasis)

★リンクテーブル★

リンク元

「皮膚弛緩症」

Dermatochalasis
Classification and external resources
Specialty	medical genetics
ICD-10	H02.3 or Q10.0
ICD-9-CM	374.87
OMIM	219200
DiseasesDB	29439

　　[★]

英: loose skin, dermatochalasis, dermatochalazia, chalastodermia
ラ: cutis laxa
同: 弛緩性皮膚, halazodermia, dermatomegaly
ICD-10: Q828
関: 遺伝性皮膚疾患

概念

NEL.2717

heterogenousな疾患概念
常染色体劣性(fibulin 5 gene)、常染色体優性(elastin and fibulin5 gene)、後天性
後天性のcutis laxaは無熱性疾患、炎症性皮膚疾患(紅斑性狼瘡、多型紅斑、アミロイドーシス、蕁麻疹、血管浮腫、ペニシリン過敏反応)に罹患した後に生じたり、あるいはペニシラミンを摂取した女性からの出生児に見られる。

遺伝子座

gene/locus	name	location	OMIM#
ADCL1	cutis laxa, autosomal dominant 1	14q32.1, 7q11.2	123700
ADCL2	cutis laxa, autosomal dominant 2		614434
ARCL1A	cutis laxa, autosomal recessive, type IA	14q32.1, 11q13	219100
ARCL1B	cutis laxa, autosomal recessive, type IB		614437
ARCL1C	cutis laxa, autosomal recessive, type IC	19q13.1-q13.2	613177
ARCL2A	cutis laxa, autosomal recessive, type IIA	12q24.3	219200
ARCL2B	cutis laxa, autosomal recessive, type IIB	17q25.3	612940
ARCL3A	cutis laxa, autosomal recessive, type IIIA		219150
ARCL3B	cutis laxa, autosomal recessive, type IIIB		614438
	cutis laxa, neonatal, with marfanoid phenotype		614100

鑑別診断

エーラス・ダンロス症候群、フォン・レックリングハウゼン病(神経線維腫症1型)、弾性線維性仮性黄色腫

[Cecil-1] Goldman, Lee (2011). Goldman's Cecil Medicine (24th ed.). Philadelphia: Elsevier Saunders. p. 2426. ISBN 1437727883.

[VaughanOphth-2] ^ ^a ^b ^c ^d ^e ^f Cunningham, Emmett T.; Paul Riordan-Eva (2011). "Chapter 4: Lids & Lacrimal Apparatus". Vaughan & Asbury's general ophthalmology. (18th ed.). New York: McGraw-Hill Medical. ISBN 978-0071634205.

[Medscape-3] ^ ^a ^b ^c ^d ^e ^f Gilliland, Grant. "Dermatochalasis". WebMD, LLC. Medscape. Retrieved 1 December 2012.

匿名

検索

案内

案内

dermatochalasis